181 related articles for article (PubMed ID: 15177437)
1. 3,4-Dihydroquinazoline derivatives as novel selective T-type Ca2+ channel blockers.
Lee YS; Lee BH; Park SJ; Kang SB; Rhim H; Park JY; Lee JH; Jeong SW; Lee JY
Bioorg Med Chem Lett; 2004 Jul; 14(13):3379-84. PubMed ID: 15177437
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological activity of 3,4-dihydroquinazolines for selective T-type Ca2+ channel blockers.
Rhim H; Lee YS; Park SJ; Chung BY; Lee JY
Bioorg Med Chem Lett; 2005 Jan; 15(2):283-6. PubMed ID: 15603940
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and SAR studies of a novel series of T-type calcium channel blockers.
Park SJ; Park SJ; Lee MJ; Rhim H; Kim Y; Lee JH; Chung BY; Lee JY
Bioorg Med Chem; 2006 May; 14(10):3502-11. PubMed ID: 16434203
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of novel T-type calcium channel blockers.
Choi JY; Seo HN; Lee MJ; Park SJ; Park SJ; Jeon JY; Kang JH; Pae AN; Rhim H; Lee JY
Bioorg Med Chem Lett; 2007 Jan; 17(2):471-5. PubMed ID: 17064894
[TBL] [Abstract][Full Text] [Related]
5. Novel T-type calcium channel blockers: dioxoquinazoline carboxamide derivatives.
Jo MN; Seo HJ; Kim Y; Seo SH; Rhim H; Cho YS; Cha JH; Koh HY; Choo H; Pae AN
Bioorg Med Chem; 2007 Jan; 15(1):365-73. PubMed ID: 17035033
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and SAR study of T-type calcium channel blockers. Part II.
Choe YJ; Seo HN; Jung SY; Rhim H; Kim J; Choo DJ; Lee JY
Arch Pharm (Weinheim); 2008 Oct; 341(10):661-4. PubMed ID: 18816587
[TBL] [Abstract][Full Text] [Related]
7. Morpholin-2-one derivatives as novel selective T-type Ca2+ channel blockers.
Ku IW; Cho S; Doddareddy MR; Jang MS; Keum G; Lee JH; Chung BY; Kim Y; Rhim H; Kang SB
Bioorg Med Chem Lett; 2006 Oct; 16(19):5244-8. PubMed ID: 16876404
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of novel T-type Ca2+ channel blockers.
Jung HK; Doddareddy MR; Cha JH; Rhim H; Cho YS; Koh HY; Jung BY; Pae AN
Bioorg Med Chem; 2004 Aug; 12(15):3965-70. PubMed ID: 15246072
[TBL] [Abstract][Full Text] [Related]
9. 3D pharmacophore based virtual screening of T-type calcium channel blockers.
Doddareddy MR; Choo H; Cho YS; Rhim H; Koh HY; Lee JH; Jeong SW; Pae AN
Bioorg Med Chem; 2007 Jan; 15(2):1091-105. PubMed ID: 17074493
[TBL] [Abstract][Full Text] [Related]
10. Lead discovery and optimization of T-type calcium channel blockers.
Park JH; Choi JK; Lee E; Lee JK; Rhim H; Seo SH; Kim Y; Doddareddy MR; Pae AN; Kang J; Roh EJ
Bioorg Med Chem; 2007 Feb; 15(3):1409-19. PubMed ID: 17150365
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of 1,3-dioxoisoindoline-5-carboxamide derivatives as T-type calcium channel blockers.
Kim HS; Kim Y; Doddareddy MR; Seo SH; Rhim H; Tae J; Pae AN; Choo H; Cho YS
Bioorg Med Chem Lett; 2007 Jan; 17(2):476-81. PubMed ID: 17092715
[TBL] [Abstract][Full Text] [Related]
12. T-type Ca2+ channel blockers suppress the growth of human cancer cells.
Heo JH; Seo HN; Choe YJ; Kim S; Oh CR; Kim YD; Rhim H; Choo DJ; Kim J; Lee JY
Bioorg Med Chem Lett; 2008 Jul; 18(14):3899-901. PubMed ID: 18585035
[TBL] [Abstract][Full Text] [Related]
13. Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R.
Akizuki O; Inayoshi A; Kitayama T; Yao K; Shirakura S; Sasaki K; Kusaka H; Matsubara M
Eur J Pharmacol; 2008 Apr; 584(2-3):424-34. PubMed ID: 18331727
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers.
Woo HM; Lee YS; Roh EJ; Seo SH; Song CM; Chung HJ; Pae AN; Shin KJ
Bioorg Med Chem Lett; 2011 Oct; 21(19):5910-5. PubMed ID: 21843937
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and evaluation of alpha,alpha'-disubstituted phenylacetate derivatives for T-type calcium channel blockers.
Lee HK; Lee YS; Roh EJ; Rhim H; Lee JY; Shin KJ
Bioorg Med Chem Lett; 2008 Aug; 18(15):4424-7. PubMed ID: 18625556
[TBL] [Abstract][Full Text] [Related]
16. Effects of mibefradil, a selective T-type Ca2+ channel antagonist, on sino-atrial node and ventricular myocardia.
Masumiya H; Kase J; Tanaka Y; Tanaka H; Shigenobu K
Res Commun Mol Pathol Pharmacol; 1999; 104(3):321-9. PubMed ID: 10741382
[TBL] [Abstract][Full Text] [Related]
17. Discovery of potent T-type calcium channel blocker.
Seo HN; Choi JY; Choe YJ; Kim Y; Rhim H; Lee SH; Kim J; Joo DJ; Lee JY
Bioorg Med Chem Lett; 2007 Nov; 17(21):5740-3. PubMed ID: 17869104
[TBL] [Abstract][Full Text] [Related]
18. T-type Ca2+ channel blockers prevent cardiac cell hypertrophy through an inhibition of calcineurin-NFAT3 activation as well as L-type Ca2+ channel blockers.
Horiba M; Muto T; Ueda N; Opthof T; Miwa K; Hojo M; Lee JK; Kamiya K; Kodama I; Yasui K
Life Sci; 2008 Mar; 82(11-12):554-60. PubMed ID: 18275974
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers.
Lee JE; Koh HY; Seo SH; Baek YY; Rhim H; Cho YS; Choo H; Pae AN
Bioorg Med Chem Lett; 2010 Jul; 20(14):4219-22. PubMed ID: 20621730
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and evaluation of a novel 4-aminomethyl-4-fluoropiperidine as a T-type Ca2+ channel antagonist.
Shipe WD; Barrow JC; Yang ZQ; Lindsley CW; Yang FV; Schlegel KA; Shu Y; Rittle KE; Bock MG; Hartman GD; Tang C; Ballard JE; Kuo Y; Adarayan ED; Prueksaritanont T; Zrada MM; Uebele VN; Nuss CE; Connolly TM; Doran SM; Fox SV; Kraus RL; Marino MJ; Graufelds VK; Vargas HM; Bunting PB; Hasbun-Manning M; Evans RM; Koblan KS; Renger JJ
J Med Chem; 2008 Jul; 51(13):3692-5. PubMed ID: 18540666
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
