BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 15177442)

  • 1. Lead identification of a potent benzopyranone selective estrogen receptor modulator.
    McKie JA; Bhagwat SS; Brady H; Doubleday M; Gayo L; Hickman M; Jalluri RK; Khammungkhune S; Kois A; Mortensen D; Richard N; Sapienza J; Shevlin G; Stein B; Sutherland M
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3407-10. PubMed ID: 15177442
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models.
    Brady H; Desai S; Gayo-Fung LM; Khammungkhune S; McKie JA; O'Leary E; Pascasio L; Sutherland MK; Anderson DW; Bhagwat SS; Stein B
    Cancer Res; 2002 Mar; 62(5):1439-42. PubMed ID: 11888917
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands.
    Renaud J; Bischoff SF; Buhl T; Floersheim P; Fournier B; Halleux C; Kallen J; Keller H; Schlaeppi JM; Stark W
    J Med Chem; 2003 Jul; 46(14):2945-57. PubMed ID: 12825935
    [TBL] [Abstract][Full Text] [Related]  

  • 4. On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.
    van Liempd SM; Kool J; Niessen WM; van Elswijk DE; Irth H; Vermeulen NP
    Drug Metab Dispos; 2006 Sep; 34(9):1640-9. PubMed ID: 16790557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery and synthesis of [6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]-2-(4-hydroxyphenyl)]b enzo[b]thiophene: a novel, highly potent, selective estrogen receptor modulator.
    Palkowitz AD; Glasebrook AL; Thrasher KJ; Hauser KL; Short LL; Phillips DL; Muehl BS; Sato M; Shetler PK; Cullinan GJ; Pell TR; Bryant HU
    J Med Chem; 1997 May; 40(10):1407-16. PubMed ID: 9154963
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model.
    Bläuer M; Heinonen PK; Rovio P; Ylikomi T
    Eur J Pharmacol; 2008 Sep; 592(1-3):13-8. PubMed ID: 18638473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Growth response of colon cancer cell lines to selective estrogen receptor modulators.
    Picariello L; Fiorelli G; Martineti V; Tognarini I; Pampaloni B; Tonelli F; Brandi ML
    Anticancer Res; 2003; 23(3B):2419-24. PubMed ID: 12894523
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands.
    Renaud J; Bischoff SF; Buhl T; Floersheim P; Fournier B; Geiser M; Halleux C; Kallen J; Keller H; Ramage P
    J Med Chem; 2005 Jan; 48(2):364-79. PubMed ID: 15658851
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.
    Pigeon P; Top S; Vessières A; Huché M; Hillard EA; Salomon E; Jaouen G
    J Med Chem; 2005 Apr; 48(8):2814-21. PubMed ID: 15828819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of two novel selective estrogen receptor modulators, raloxifene, tamoxifen, and ethinyl estradiol on the uterus, vagina and breast in ovariectomized cynomolgus monkeys (Macaca fascicularis).
    Sikoski P; Register TC; Lees CJ; Lundeen S; Hutchison J; Brown KH; Cline JM
    Am J Obstet Gynecol; 2007 Jan; 196(1):75.e1-7. PubMed ID: 17240242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tamoxifen and raloxifene differ in their functional interactions with aspartate 351 of estrogen receptor alpha.
    Dayan G; Lupien M; Auger A; Anghel SI; Rocha W; Croisetière S; Katzenellenbogen JA; Mader S
    Mol Pharmacol; 2006 Aug; 70(2):579-88. PubMed ID: 16679488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of estrogen-stimulated growth of uterine leiomyomas by selective estrogen receptor modulators.
    Fuchs-Young R; Howe S; Hale L; Miles R; Walker C
    Mol Carcinog; 1996 Nov; 17(3):151-9. PubMed ID: 8944075
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential response of estrogen receptors alpha and beta to SP500263, a novel potent selective estrogen receptor modulator.
    Brady H; Doubleday M; Gayo-Fung LM; Hickman M; Khammungkhune S; Kois A; Lipps S; Pierce S; Richard N; Shevlin G; Sutherland MK; Anderson DW; Bhagwat SS; Stein B
    Mol Pharmacol; 2002 Mar; 61(3):562-8. PubMed ID: 11854436
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Efficacy of selective estrogen receptor modulators in nude mice bearing human transitional cell carcinoma.
    Sonpavde G; Okuno N; Weiss H; Yu J; Shen SS; Younes M; Jian W; Lerner SP; Smith CL
    Urology; 2007 Jun; 69(6):1221-6. PubMed ID: 17572228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents.
    Jordan VC
    J Med Chem; 2003 Mar; 46(7):1081-111. PubMed ID: 12646017
    [No Abstract]   [Full Text] [Related]  

  • 16. Raloxifene blocks estradiol induction of the serotonin transporter and 5-hydroxytryptamine2A receptor in female rat brain.
    Sumner BE; Grant KE; Rosie R; Hegele-Hartung Ch; Fritzemeier KH; Fink G
    Neurosci Lett; 2007 Apr; 417(1):95-9. PubMed ID: 17398000
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Gene expression changes induced by estrogen and selective estrogen receptor modulators in primary-cultured human endometrial cells: signals that distinguish the human carcinogen tamoxifen.
    Pole JC; Gold LI; Orton T; Huby R; Carmichael PL
    Toxicology; 2005 Jan; 206(1):91-109. PubMed ID: 15590111
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The effects of the selective estrogen receptor modulators, methyl-piperidino-pyrazole (MPP), and raloxifene in normal and cancerous endometrial cell lines and in the murine uterus.
    Davis AM; Ellersieck MR; Grimm KM; Rosenfeld CS
    Mol Reprod Dev; 2006 Aug; 73(8):1034-44. PubMed ID: 16688783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular simulation of interaction between estrogen receptor and selective estrogen receptor modulators.
    Guo ZR; Yi X; Xu ZB
    Acta Pharmacol Sin; 2002 Mar; 23(3):208-12. PubMed ID: 11918843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells.
    Hui AM; Zhang W; Chen W; Xi D; Purow B; Friedman GC; Fine HA
    Cancer Res; 2004 Dec; 64(24):9115-23. PubMed ID: 15604281
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.