BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 15177465)

  • 21. 3-(4-phenoxyphenyl)pyrazoles: a novel class of sodium channel blockers.
    Yang J; Gharagozloo P; Yao J; Ilyin VI; Carter RB; Nguyen P; Robledo S; Woodward RM; Hogenkamp DJ
    J Med Chem; 2004 Mar; 47(6):1547-52. PubMed ID: 14998340
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Na+ currents in cardioprotection: better to be late.
    Le Grand B; Pignier C; Létienne R; Colpaert F; Cuisiat F; Rolland F; Mas A; Borras M; Vacher B
    J Med Chem; 2009 Jul; 52(14):4149-60. PubMed ID: 19514733
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Binding of sodium channel inhibitors to hyperpolarized and depolarized conformations of the channel.
    Lenkey N; Karoly R; Epresi N; Vizi E; Mike A
    Neuropharmacology; 2011 Jan; 60(1):191-200. PubMed ID: 20713065
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and biological evaluation of pyrrolidine derivatives as novel and potent sodium channel blockers for the treatment of ischemic stroke.
    Seki M; Tsuruta O; Tatsumi R; Soejima A
    Bioorg Med Chem Lett; 2013 Jul; 23(14):4230-4. PubMed ID: 23743284
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effects of EGCG on voltage-gated sodium channels in primary cultures of rat hippocampal CA1 neurons.
    Deng HM; Yin ST; Yan D; Tang ML; Li CC; Chen JT; Wang M; Ruan DY
    Toxicology; 2008 Oct; 252(1-3):1-8. PubMed ID: 18706964
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Flecainide inhibits the stimulatory effect of veratridine on the response of airway mechanoreceptors to maintained inflations in rats.
    Matsumoto S; Takahashi M; Iwasaki K; Ide R; Saiki C; Takeda M
    Life Sci; 2010 Sep; 87(13-14):411-9. PubMed ID: 20736024
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Synthesis and in vitro evaluation of 2,4-diamino-1,3,5-triazine derivatives as neuronal voltage-gated sodium channel blockers.
    Ma X; Poon TY; Wong PT; Chui WK
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5644-7. PubMed ID: 19716698
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Effects of dextrorotatory morphinans on brain Na+ channels expressed in Xenopus oocytes.
    Lee JH; Shin EJ; Jeong SM; Lee BH; Yoon IS; Lee JH; Choi SH; Kim YH; Pyo MK; Lee SM; Chae JS; Rhim H; Oh JW; Kim HC; Nah SY
    Eur J Pharmacol; 2007 Jun; 564(1-3):7-17. PubMed ID: 17346698
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The effect of kappa-opioid receptor agonists on tetrodotoxin-resistant sodium channels in primary sensory neurons.
    Su X; Castle NA; Antonio B; Roeloffs R; Thomas JB; Krafte DS; Chapman ML
    Anesth Analg; 2009 Aug; 109(2):632-40. PubMed ID: 19608841
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain.
    Shao PP; Ok D; Fisher MH; Garcia ML; Kaczorowski GJ; Li C; Lyons KA; Martin WJ; Meinke PT; Priest BT; Smith MM; Wyvratt MJ; Ye F; Parsons WH
    Bioorg Med Chem Lett; 2005 Apr; 15(7):1901-7. PubMed ID: 15780630
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design, synthesis, and structure-activity relationships of novel 2-substituted pyrazinoylguanidine epithelial sodium channel blockers: drugs for cystic fibrosis and chronic bronchitis.
    Hirsh AJ; Molino BF; Zhang J; Astakhova N; Geiss WB; Sargent BJ; Swenson BD; Usyatinsky A; Wyle MJ; Boucher RC; Smith RT; Zamurs A; Johnson MR
    J Med Chem; 2006 Jul; 49(14):4098-115. PubMed ID: 16821771
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel drug binding site on voltage-gated sodium channels in rat brain.
    Riddall DR; Leach MJ; Garthwaite J
    Mol Pharmacol; 2006 Jan; 69(1):278-87. PubMed ID: 16219909
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Na(v)1.7 antagonists.
    Chakka N; Bregman H; Du B; Nguyen HN; Buchanan JL; Feric E; Ligutti J; Liu D; McDermott JS; Zou A; McDonough SI; Dimauro EF
    Bioorg Med Chem Lett; 2012 Mar; 22(5):2052-62. PubMed ID: 22318156
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of Sodium Ion Channel Function with Truncated Forms of Batrachotoxin.
    Toma T; Logan MM; Menard F; Devlin AS; Du Bois J
    ACS Chem Neurosci; 2016 Oct; 7(10):1463-1468. PubMed ID: 27501251
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.
    Sandtner W; Szendroedi J; Zarrabi T; Zebedin E; Hilber K; Glaaser I; Fozzard HA; Dudley SC; Todt H
    Mol Pharmacol; 2004 Sep; 66(3):648-57. PubMed ID: 15322257
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Substituted biaryl pyrazoles as sodium channel blockers.
    Tyagarajan S; Chakravarty PK; Zhou B; Taylor B; Fisher MH; Wyvratt MJ; Lyons K; Klatt T; Li X; Kumar S; Williams B; Felix J; Priest BT; Brochu RM; Warren V; Smith M; Garcia M; Kaczorowski GJ; Martin WJ; Abbadie C; McGowan E; Jochnowitz N; Parsons WH
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5480-3. PubMed ID: 20709545
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Vinpocetine blockade of sodium channels inhibits the rise in sodium and calcium induced by 4-aminopyridine in synaptosomes.
    Sitges M; Galván E; Nekrassov V
    Neurochem Int; 2005 Jun; 46(7):533-40. PubMed ID: 15843047
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Potent analgesic effects of a putative sodium channel blocker M58373 on formalin-induced and neuropathic pain in rats.
    Akada Y; Ogawa S; Amano K; Fukudome Y; Yamasaki F; Itoh M; Yamamoto I
    Eur J Pharmacol; 2006 May; 536(3):248-55. PubMed ID: 16603152
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Modulation of Na+ transport and epithelial sodium channel expression by protein kinase C in rat alveolar epithelial cells.
    Yamagata T; Yamagata Y; Massé C; Tessier MC; Brochiero E; Dagenais A; Berthiaume Y
    Can J Physiol Pharmacol; 2005 Nov; 83(11):977-87. PubMed ID: 16391706
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A high concentration of resiniferatoxin inhibits ion channel function in clonal neuroendocrine cells.
    Sugimoto K; Kissin I; Strichartz G
    Anesth Analg; 2008 Jul; 107(1):318-24. PubMed ID: 18635503
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.