BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 15177473)

  • 1. Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall.
    Gobec S; Plantan I; Mravljak J; Wilson RA; Besra GS; Kikelj D
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3559-62. PubMed ID: 15177473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of sugar-derived esters, alpha-ketoesters and alpha-ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C.
    Sanki AK; Boucau J; Umesiri FE; Ronning DR; Sucheck SJ
    Mol Biosyst; 2009 Sep; 5(9):945-56. PubMed ID: 19668859
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New lipophilic phthalimido- and 3-phenoxybenzyl sulfonates: inhibition of antigen 85C mycolyltransferase activity and cytotoxicity.
    Kovac A; Wilson RA; Besra GS; Filipic M; Kikelj D; Gobec S
    J Enzyme Inhib Med Chem; 2006 Aug; 21(4):391-7. PubMed ID: 17059171
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines.
    Ronning DR; Klabunde T; Besra GS; Vissa VD; Belisle JT; Sacchettini JC
    Nat Struct Biol; 2000 Feb; 7(2):141-6. PubMed ID: 10655617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall.
    Gobec S; Plantan I; Mravljak J; Svajger U; Wilson RA; Besra GS; Soares SL; Appelberg R; Kikelj D
    Eur J Med Chem; 2007 Jan; 42(1):54-63. PubMed ID: 17010479
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Another brick in the wall.
    Tonge PJ
    Nat Struct Biol; 2000 Feb; 7(2):94-6. PubMed ID: 10655605
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase.
    Anderson DH; Harth G; Horwitz MA; Eisenberg D
    J Mol Biol; 2001 Mar; 307(2):671-81. PubMed ID: 11254389
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The mycolyltransferase 85A, a putative drug target of Mycobacterium tuberculosis: development of a novel assay and quantification of glycolipid-status of the mycobacterial cell wall.
    Elamin AA; Stehr M; Oehlmann W; Singh M
    J Microbiol Methods; 2009 Dec; 79(3):358-63. PubMed ID: 19857528
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of new inhibitors of UDP-Galf transferase--a key enzyme in M. tuberculosis cell wall biosynthesis.
    Cren S; Gurcha SS; Blake AJ; Besra GS; Thomas NR
    Org Biomol Chem; 2004 Sep; 2(17):2418-20. PubMed ID: 15326520
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cyclipostins and cyclophostin analogs inhibit the antigen 85C from
    Viljoen A; Richard M; Nguyen PC; Fourquet P; Camoin L; Paudal RR; Gnawali GR; Spilling CD; Cavalier JF; Canaan S; Blaise M; Kremer L
    J Biol Chem; 2018 Feb; 293(8):2755-2769. PubMed ID: 29301937
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives.
    Goins CM; Dajnowicz S; Thanna S; Sucheck SJ; Parks JM; Ronning DR
    ACS Infect Dis; 2017 May; 3(5):378-387. PubMed ID: 28285521
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A coupled assay measuring Mycobacterium tuberculosis antigen 85C enzymatic activity.
    Boucau J; Sanki AK; Voss BJ; Sucheck SJ; Ronning DR
    Anal Biochem; 2009 Feb; 385(1):120-7. PubMed ID: 18992216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational screening for new inhibitors of M. tuberculosis mycolyltransferases antigen 85 group of proteins as potential drug targets.
    Gahoi S; Mandal RS; Ivanisenko N; Shrivastava P; Jain S; Singh AK; Raghunandanan MV; Kanchan S; Taneja B; Mandal C; Ivanisenko VA; Kumar A; Kumar R; ; Ramachandran S
    J Biomol Struct Dyn; 2013; 31(1):30-43. PubMed ID: 22804492
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel small molecule inhibitors of MDR Mycobacterium tuberculosis by NMR fragment screening of antigen 85C.
    Scheich C; Puetter V; Schade M
    J Med Chem; 2010 Dec; 53(23):8362-7. PubMed ID: 21073150
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity.
    Ronning DR; Vissa V; Besra GS; Belisle JT; Sacchettini JC
    J Biol Chem; 2004 Aug; 279(35):36771-7. PubMed ID: 15192106
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Control of cell wall assembly by a histone-like protein in Mycobacteria.
    Katsube T; Matsumoto S; Takatsuka M; Okuyama M; Ozeki Y; Naito M; Nishiuchi Y; Fujiwara N; Yoshimura M; Tsuboi T; Torii M; Oshitani N; Arakawa T; Kobayashi K
    J Bacteriol; 2007 Nov; 189(22):8241-9. PubMed ID: 17873049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and X-ray analysis of a glycoconjugate bound to Mycobacterium tuberculosis antigen 85C.
    Ibrahim DA; Boucau J; Lajiness DH; Veleti SK; Trabbic KR; Adams SS; Ronning DR; Sucheck SJ
    Bioconjug Chem; 2012 Dec; 23(12):2403-16. PubMed ID: 23190459
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mycolyltransferase from
    Goins CM; Dajnowicz S; Smith MD; Parks JM; Ronning DR
    J Biol Chem; 2018 Mar; 293(10):3651-3662. PubMed ID: 29352107
    [No Abstract]   [Full Text] [Related]  

  • 19. Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads.
    West NP; Cergol KM; Xue M; Randall EJ; Britton WJ; Payne RJ
    Chem Commun (Camb); 2011 May; 47(18):5166-8. PubMed ID: 21384024
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid transport in Mycobacterium tuberculosis and its implications in virulence and drug development.
    Bailo R; Bhatt A; AĆ­nsa JA
    Biochem Pharmacol; 2015 Aug; 96(3):159-67. PubMed ID: 25986884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.