BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

511 related articles for article (PubMed ID: 15181248)

  • 21. Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease.
    Mahley RW; Nathan BP; Pitas RE
    Ann N Y Acad Sci; 1996 Jan; 777():139-45. PubMed ID: 8624076
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Apolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in mice.
    Gong JS; Kobayashi M; Hayashi H; Zou K; Sawamura N; Fujita SC; Yanagisawa K; Michikawa M
    J Biol Chem; 2002 Aug; 277(33):29919-26. PubMed ID: 12042316
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma.
    Yang DS; Smith JD; Zhou Z; Gandy SE; Martins RN
    J Neurochem; 1997 Feb; 68(2):721-5. PubMed ID: 9003062
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.
    Fagan AM; Watson M; Parsadanian M; Bales KR; Paul SM; Holtzman DM
    Neurobiol Dis; 2002 Apr; 9(3):305-18. PubMed ID: 11950276
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Macrophage-mediated degradation of beta-amyloid via an apolipoprotein E isoform-dependent mechanism.
    Zhao L; Lin S; Bales KR; Gelfanova V; Koger D; Delong C; Hale J; Liu F; Hunter JM; Paul SM
    J Neurosci; 2009 Mar; 29(11):3603-12. PubMed ID: 19295164
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice.
    Bien-Ly N; Gillespie AK; Walker D; Yoon SY; Huang Y
    J Neurosci; 2012 Apr; 32(14):4803-11. PubMed ID: 22492035
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Apolipoprotein E and apolipoprotein E receptors modulate A beta-induced glial neuroinflammatory responses.
    LaDu MJ; Shah JA; Reardon CA; Getz GS; Bu G; Hu J; Guo L; Van Eldik LJ
    Neurochem Int; 2001; 39(5-6):427-34. PubMed ID: 11578778
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro.
    Iannucci J; Sen A; Grammas P
    Curr Issues Mol Biol; 2021 May; 43(1):215-225. PubMed ID: 34071762
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Astrocytes down-regulate neuronal beta-amyloid precursor protein expression and modify its processing in an apolipoprotein E isoform-specific manner.
    Vincent B; Smith JD
    Eur J Neurosci; 2001 Jul; 14(2):256-66. PubMed ID: 11553277
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
    Tai LM; Bilousova T; Jungbauer L; Roeske SK; Youmans KL; Yu C; Poon WW; Cornwell LB; Miller CA; Vinters HV; Van Eldik LJ; Fardo DW; Estus S; Bu G; Gylys KH; Ladu MJ
    J Biol Chem; 2013 Feb; 288(8):5914-26. PubMed ID: 23293020
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice.
    Ophir G; Meilin S; Efrati M; Chapman J; Karussis D; Roses A; Michaelson DM
    Neurobiol Dis; 2003 Feb; 12(1):56-64. PubMed ID: 12609489
    [TBL] [Abstract][Full Text] [Related]  

  • 32. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress.
    Colton CA; Brown CM; Cook D; Needham LK; Xu Q; Czapiga M; Saunders AM; Schmechel DE; Rasheed K; Vitek MP
    Neurobiol Aging; 2002; 23(5):777-85. PubMed ID: 12392781
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target.
    Ye S; Huang Y; Müllendorff K; Dong L; Giedt G; Meng EC; Cohen FE; Kuntz ID; Weisgraber KH; Mahley RW
    Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18700-5. PubMed ID: 16344478
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex.
    Arold S; Sullivan P; Bilousova T; Teng E; Miller CA; Poon WW; Vinters HV; Cornwell LB; Saing T; Cole GM; Gylys KH
    Acta Neuropathol; 2012 Jan; 123(1):39-52. PubMed ID: 22020632
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention.
    Keeney JT; Ibrahimi S; Zhao L
    J Alzheimers Dis; 2015; 48(2):411-24. PubMed ID: 26402005
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells.
    Yamauchi K; Tozuka M; Hidaka H; Nakabayashi T; Sugano M; Katsuyama T
    Ann Clin Lab Sci; 2002; 32(1):65-74. PubMed ID: 11848621
    [TBL] [Abstract][Full Text] [Related]  

  • 37. An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction.
    Wang H; Durham L; Dawson H; Song P; Warner DS; Sullivan PM; Vitek MP; Laskowitz DT
    Neuroscience; 2007 Feb; 144(4):1324-33. PubMed ID: 17187933
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Calcium-dependent cytosolic phospholipase A
    Wang S; Li B; Solomon V; Fonteh A; Rapoport SI; Bennett DA; Arvanitakis Z; Chui HC; Miller C; Sullivan PM; Wang HY; Yassine HN
    Mol Neurodegener; 2021 Apr; 16(1):26. PubMed ID: 33863362
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Impaired Autophagy in APOE4 Astrocytes.
    Simonovitch S; Schmukler E; Bespalko A; Iram T; Frenkel D; Holtzman DM; Masliah E; Michaelson DM; Pinkas-Kramarski R
    J Alzheimers Dis; 2016; 51(3):915-27. PubMed ID: 26923027
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior.
    Grootendorst J; Bour A; Vogel E; Kelche C; Sullivan PM; Dodart JC; Bales K; Mathis C
    Behav Brain Res; 2005 Apr; 159(1):1-14. PubMed ID: 15794991
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 26.