BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 15185369)

  • 1. Immunological optimization of a generic hydrophobic pocket for high affinity hapten binding and Diels-Alder activity.
    Piatesi A; Hilvert D
    Chembiochem; 2004 Apr; 5(4):460-6. PubMed ID: 15185369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies.
    Ulrich HD; Schultz PG
    J Mol Biol; 1998 Jan; 275(1):95-111. PubMed ID: 9451442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Switching antibody specificity through minimal mutation.
    Piatesi A; Aldag C; Hilvert D
    J Mol Biol; 2008 Apr; 377(4):993-1001. PubMed ID: 18295792
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression improvement and mechanistic study of the retro-Diels-Alderase catalytic antibody 10F11 by site-directed mutagenesis.
    Zheng L; Goddard JP; Baumann U; Reymond JL
    J Mol Biol; 2004 Aug; 341(3):807-14. PubMed ID: 15288788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The three-dimensional structure of a complex of a murine Fab (NC10. 14) with a potent sweetener (NC174): an illustration of structural diversity in antigen recognition by immunoglobulins.
    Guddat LW; Shan L; Broomell C; Ramsland PA; Fan Z; Anchin JM; Linthicum DS; Edmundson AB
    J Mol Biol; 2000 Sep; 302(4):853-72. PubMed ID: 10993728
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A comparison of the crystallographic structures of two catalytic antibodies with esterase activity.
    Buchbinder JL; Stephenson RC; Scanlan TS; Fletterick RJ
    J Mol Biol; 1998 Oct; 282(5):1033-41. PubMed ID: 9753552
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.
    Larsen NA; Heine A; Crane L; Cravatt BF; Lerner RA; Wilson IA
    J Mol Biol; 2001 Nov; 314(1):93-102. PubMed ID: 11724535
    [TBL] [Abstract][Full Text] [Related]  

  • 8. N-terminal mutations in the anti-estradiol Fab 57-2 modify its hapten binding properties.
    Saviranta PJauria P; Lamminmäki U; Hellman J; Eriksson S; Lövgren T
    Protein Sci; 2000 Dec; 9(12):2547-56. PubMed ID: 11206076
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutational analysis of the affinity maturation of antibody 48G7.
    Yang PL; Schultz PG
    J Mol Biol; 1999 Dec; 294(5):1191-201. PubMed ID: 10600377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conservation of binding site geometry among p-azophenylarsonate-specific antibodies.
    Parhami-Seren B; Kussie PH; Strong RK; Margolies MN
    J Immunol; 1993 Mar; 150(5):1829-37. PubMed ID: 8436818
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
    Hotta K; Lange H; Tantillo DJ; Houk KN; Hilvert D; Wilson IA
    J Mol Biol; 2000 Oct; 302(5):1213-25. PubMed ID: 11183784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic and fluorescence studies of affinity maturation in related antibodies.
    Pauyo T; Hilinski GJ; Chiu PT; Hansen DE; Choi YJ; Ratner DI; Shah-Mahoney N; Southern CA; O'Hara PB
    Mol Immunol; 2006 Mar; 43(7):812-21. PubMed ID: 16137768
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural analysis of altered large-subunit loop-6/carboxy-terminus interactions that influence catalytic efficiency and CO2/O2 specificity of ribulose-1,5-bisphosphate carboxylase/oxygenase.
    Karkehabadi S; Satagopan S; Taylor TC; Spreitzer RJ; Andersson I
    Biochemistry; 2007 Oct; 46(39):11080-9. PubMed ID: 17824672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
    Monnet C; Bettsworth F; Stura EA; Le Du MH; Ménez R; Derrien L; Zinn-Justin S; Gilquin B; Sibaï G; Battail-Poirot N; Jolivet M; Ménez A; Arnaud M; Ducancel F; Charbonnier JB
    J Mol Biol; 2002 Jan; 315(4):699-712. PubMed ID: 11812141
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shape complementarity, binding-site dynamics, and transition state stabilization: a theoretical study of Diels-Alder catalysis by antibody 1E9.
    Chen J; Deng Q; Wang R; Houk K; Hilvert D
    Chembiochem; 2000 Nov; 1(4):255-61. PubMed ID: 11828417
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme.
    Katsemi V; Lücke C; Koepke J; Löhr F; Maurer S; Fritzsch G; Rüterjans H
    Biochemistry; 2005 Jun; 44(25):9022-33. PubMed ID: 15966726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of functionally important residues in the pyridoxal-5'-phosphate-dependent catalytic antibody 15A9.
    Mouratou B; Stetefeld J
    Biochemistry; 2004 Jun; 43(21):6612-9. PubMed ID: 15157094
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional requirements for the optimal catalytic configuration of the AChE active center.
    Shafferman A; Barak D; Kaplan D; Ordentlich A; Kronman C; Velan B
    Chem Biol Interact; 2005 Dec; 157-158():123-31. PubMed ID: 16256968
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution.
    Kristensen O; Vassylyev DG; Tanaka F; Morikawa K; Fujii I
    J Mol Biol; 1998 Aug; 281(3):501-11. PubMed ID: 9698565
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis for antibody catalysis of a disfavored ring closure reaction.
    Gruber K; Zhou B; Houk KN; Lerner RA; Shevlin CG; Wilson IA
    Biochemistry; 1999 Jun; 38(22):7062-74. PubMed ID: 10353817
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.