These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 15190064)

  • 1. A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone.
    Kakizaki I; Kojima K; Takagaki K; Endo M; Kannagi R; Ito M; Maruo Y; Sato H; Yasuda T; Mita S; Kimata K; Itano N
    J Biol Chem; 2004 Aug; 279(32):33281-9. PubMed ID: 15190064
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3.
    Kultti A; Pasonen-Seppänen S; Jauhiainen M; Rilla KJ; Kärnä R; Pyöriä E; Tammi RH; Tammi MI
    Exp Cell Res; 2009 Jul; 315(11):1914-23. PubMed ID: 19285976
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of 4-methylumbelliferone on cell-free synthesis of hyaluronic acid.
    Nakamura T; Funahashi M; Takagaki K; Munakata H; Tanaka K; Saito Y; Endo M
    Biochem Mol Biol Int; 1997 Oct; 43(2):263-8. PubMed ID: 9350333
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone.
    Kakizaki I; Takagaki K; Endo Y; Kudo D; Ikeya H; Miyoshi T; Baggenstoss BA; Tlapak-Simmons VL; Kumari K; Nakane A; Weigel PH; Endo M
    Eur J Biochem; 2002 Oct; 269(20):5066-75. PubMed ID: 12383266
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of hyaluronan synthesis in breast cancer cells by 4-methylumbelliferone suppresses tumorigenicity in vitro and metastatic lesions of bone in vivo.
    Urakawa H; Nishida Y; Wasa J; Arai E; Zhuo L; Kimata K; Kozawa E; Futamura N; Ishiguro N
    Int J Cancer; 2012 Jan; 130(2):454-66. PubMed ID: 21387290
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.
    Twarock S; Freudenberger T; Poscher E; Dai G; Jannasch K; Dullin C; Alves F; Prenzel K; Knoefel WT; Stoecklein NH; Savani RC; Homey B; Fischer JW
    Mol Cancer; 2011 Mar; 10():30. PubMed ID: 21429221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Study of hyaluronan synthase inhibitor, 4-methylumbelliferone derivatives on human pancreatic cancer cell (KP1-NL).
    Morohashi H; Kon A; Nakai M; Yamaguchi M; Kakizaki I; Yoshihara S; Sasaki M; Takagaki K
    Biochem Biophys Res Commun; 2006 Jul; 345(4):1454-9. PubMed ID: 16730656
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of 4-methylumbelliferone on hyaluronan synthesis, MMP2 activity, proliferation, and motility of human aortic smooth muscle cells.
    Vigetti D; Rizzi M; Viola M; Karousou E; Genasetti A; Clerici M; Bartolini B; Hascall VC; De Luca G; Passi A
    Glycobiology; 2009 May; 19(5):537-46. PubMed ID: 19240269
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition.
    Nagy N; Gurevich I; Kuipers HF; Ruppert SM; Marshall PL; Xie BJ; Sun W; Malkovskiy AV; Rajadas J; Grandoch M; Fischer JW; Frymoyer AR; Kaber G; Bollyky PL
    J Biol Chem; 2019 May; 294(19):7864-7877. PubMed ID: 30914479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-Methylumbelliferone inhibits the phosphorylation of hyaluronan synthase 2 induced by 12-O-tetradecanoyl-phorbol-13-acetate.
    Kuroda Y; Kasai K; Nanashima N; Nozaka H; Nakano M; Chiba M; Yoneda M; Nakamura T
    Biomed Res; 2013 Apr; 34(2):97-103. PubMed ID: 23594483
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4-Methylumbelliferone Suppresses Hyaluronan Synthesis and Tumor Progression in SCID Mice Intra-abdominally Inoculated With Pancreatic Cancer Cells.
    Nagase H; Kudo D; Suto A; Yoshida E; Suto S; Negishi M; Kakizaki I; Hakamada K
    Pancreas; 2017 Feb; 46(2):190-197. PubMed ID: 27846148
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hyaluronan synthesis is required for IL-2-mediated T cell proliferation.
    Mahaffey CL; Mummert ME
    J Immunol; 2007 Dec; 179(12):8191-9. PubMed ID: 18056362
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The hyaluronic acid inhibitor 4-methylumbelliferone is an NSMase2 activator-role of Ceramide in MU anti-tumor activity.
    Qin J; Kilkus J; Dawson G
    Biochim Biophys Acta; 2016 Feb; 1861(2):78-90. PubMed ID: 26548718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties.
    Itano N; Sawai T; Yoshida M; Lenas P; Yamada Y; Imagawa M; Shinomura T; Hamaguchi M; Yoshida Y; Ohnuki Y; Miyauchi S; Spicer AP; McDonald JA; Kimata K
    J Biol Chem; 1999 Aug; 274(35):25085-92. PubMed ID: 10455188
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective expression and functional characteristics of three mammalian hyaluronan synthases in oncogenic malignant transformation.
    Itano N; Sawai T; Atsumi F; Miyaishi O; Taniguchi S; Kannagi R; Hamaguchi M; Kimata K
    J Biol Chem; 2004 Apr; 279(18):18679-87. PubMed ID: 14724275
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts.
    Yoshioka Y; Kozawa E; Urakawa H; Arai E; Futamura N; Zhuo L; Kimata K; Ishiguro N; Nishida Y
    Arthritis Rheum; 2013 May; 65(5):1160-70. PubMed ID: 23335273
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of a hyaluronan synthase suppressor, 4-methylumbelliferone, on B16F-10 melanoma cell adhesion and locomotion.
    Kudo D; Kon A; Yoshihara S; Kakizaki I; Sasaki M; Endo M; Takagaki K
    Biochem Biophys Res Commun; 2004 Sep; 321(4):783-7. PubMed ID: 15358095
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase.
    Clarkin CE; Allen S; Wheeler-Jones CP; Bastow ER; Pitsillides AA
    Matrix Biol; 2011 Apr; 30(3):163-8. PubMed ID: 21292001
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro inhibitory effects of non-steroidal anti-inflammatory drugs on 4-methylumbelliferone glucuronidation in recombinant human UDP-glucuronosyltransferase 1A9--potent inhibition by niflumic acid.
    Mano Y; Usui T; Kamimura H
    Biopharm Drug Dispos; 2006 Jan; 27(1):1-6. PubMed ID: 16278927
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.