BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 15197260)

  • 1. Protein tolerance to random amino acid change.
    Guo HH; Choe J; Loeb LA
    Proc Natl Acad Sci U S A; 2004 Jun; 101(25):9205-10. PubMed ID: 15197260
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing beta-lactamase structure and function using random replacement mutagenesis.
    Palzkill T; Botstein D
    Proteins; 1992 Sep; 14(1):29-44. PubMed ID: 1329081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A statistical analysis of random mutagenesis methods used for directed protein evolution.
    Wong TS; Roccatano D; Zacharias M; Schwaneberg U
    J Mol Biol; 2006 Jan; 355(4):858-71. PubMed ID: 16325201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lessons from diversity of directed evolution experiments by an analysis of 3,000 mutations.
    Zhao J; Kardashliev T; Joëlle Ruff A; Bocola M; Schwaneberg U
    Biotechnol Bioeng; 2014 Dec; 111(12):2380-9. PubMed ID: 24904008
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amino acid substitutions in random mutagenesis libraries: lessons from analyzing 3000 mutations.
    Zhao J; Frauenkron-Machedjou VJ; Kardashliev T; Ruff AJ; Zhu L; Bocola M; Schwaneberg U
    Appl Microbiol Biotechnol; 2017 Apr; 101(8):3177-3187. PubMed ID: 28050632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutagenic mapping of helical structures in the transmembrane segments of the yeast alpha-factor receptor.
    Martin NP; Celić A; Dumont ME
    J Mol Biol; 2002 Apr; 317(5):765-88. PubMed ID: 11955023
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
    Morikawa K; Ariyoshi M; Vassylyev DG; Matsumoto O; Katayanagi K; Ohtsuka E
    J Mol Biol; 1995 Jun; 249(2):360-75. PubMed ID: 7783199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Predicting the tolerance of proteins to random amino acid substitution.
    Wilke CO; Bloom JD; Drummond DA; Raval A
    Biophys J; 2005 Dec; 89(6):3714-20. PubMed ID: 16150971
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNA mutagenesis yields highly diverse mRNA libraries for in vitro protein evolution.
    Kopsidas G; Carman RK; Stutt EL; Raicevic A; Roberts AS; Siomos MA; Dobric N; Pontes-Braz L; Coia G
    BMC Biotechnol; 2007 Apr; 7():18. PubMed ID: 17425805
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heterotachy and functional shift in protein evolution.
    Philippe H; Casane D; Gribaldo S; Lopez P; Meunier J
    IUBMB Life; 2003; 55(4-5):257-65. PubMed ID: 12880207
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor.
    Burstein ES; Spalding TA; Brann MR
    Biochemistry; 1998 Mar; 37(12):4052-8. PubMed ID: 9521726
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active TEM-1 beta-lactamase mutants with random peptides inserted in three contiguous surface loops.
    Mathonet P; Deherve J; Soumillion P; Fastrez J
    Protein Sci; 2006 Oct; 15(10):2323-34. PubMed ID: 16963643
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effects of steric mutations on the structure of type III antifreeze protein and its interaction with ice.
    DeLuca CI; Davies PL; Ye Q; Jia Z
    J Mol Biol; 1998 Jan; 275(3):515-25. PubMed ID: 9466928
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein design through systematic catalytic loop exchange in the (beta/alpha)8 fold.
    Ochoa-Leyva A; Soberón X; Sánchez F; Argüello M; Montero-Morán G; Saab-Rincón G
    J Mol Biol; 2009 Apr; 387(4):949-64. PubMed ID: 19233201
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Probing the alpha-complementing domain of E. coli beta-galactosidase with use of an insertional pentapeptide mutagenesis strategy based on Mu in vitro DNA transposition.
    Poussu E; Vihinen M; Paulin L; Savilahti H
    Proteins; 2004 Mar; 54(4):681-92. PubMed ID: 14997564
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Prediction of deleterious functional effects of amino acid mutations using a library of structure-based function descriptors.
    Herrgard S; Cammer SA; Hoffman BT; Knutson S; Gallina M; Speir JA; Fetrow JS; Baxter SM
    Proteins; 2003 Dec; 53(4):806-16. PubMed ID: 14635123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improving the thermostability of Geobacillus stearothermophilus xylanase XT6 by directed evolution and site-directed mutagenesis.
    Zhang ZG; Yi ZL; Pei XQ; Wu ZL
    Bioresour Technol; 2010 Dec; 101(23):9272-8. PubMed ID: 20691586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary convergence in adaptation of proteins to temperature: A4-lactate dehydrogenases of Pacific damselfishes (Chromis spp.).
    Johns GC; Somero GN
    Mol Biol Evol; 2004 Feb; 21(2):314-20. PubMed ID: 14660697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily.
    Schmidt DM; Mundorff EC; Dojka M; Bermudez E; Ness JE; Govindarajan S; Babbitt PC; Minshull J; Gerlt JA
    Biochemistry; 2003 Jul; 42(28):8387-93. PubMed ID: 12859183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evolutionary potential of (beta/alpha)8-barrels: in vitro enhancement of a "new" reaction in the enolase superfamily.
    Vick JE; Schmidt DM; Gerlt JA
    Biochemistry; 2005 Sep; 44(35):11722-9. PubMed ID: 16128573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.