BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

444 related articles for article (PubMed ID: 15198993)

  • 1. Pms2 is a genetic enhancer of trinucleotide CAG.CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion.
    Gomes-Pereira M; Fortune MT; Ingram L; McAbney JP; Monckton DG
    Hum Mol Genet; 2004 Aug; 13(16):1815-25. PubMed ID: 15198993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pms2 suppresses large expansions of the (GAA·TTC)n sequence in neuronal tissues.
    Bourn RL; De Biase I; Pinto RM; Sandi C; Al-Mahdawi S; Pook MA; Bidichandani SI
    PLoS One; 2012; 7(10):e47085. PubMed ID: 23071719
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients.
    Morales F; Vásquez M; Santamaría C; Cuenca P; Corrales E; Monckton DG
    DNA Repair (Amst); 2016 Apr; 40():57-66. PubMed ID: 26994442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
    Chen PC; Dudley S; Hagen W; Dizon D; Paxton L; Reichow D; Yoon SR; Yang K; Arnheim N; Liskay RM; Lipkin SM
    Cancer Res; 2005 Oct; 65(19):8662-70. PubMed ID: 16204034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer.
    Chen Y; Wang J; Fraig MM; Henderson K; Bissada NK; Watson DK; Schweinfest CW
    Int J Oncol; 2003 May; 22(5):1033-43. PubMed ID: 12684669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
    Ezzatizadeh V; Sandi C; Sandi M; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(6):e100523. PubMed ID: 24971578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Visualization of mosaicism in tissues of normal and mismatch-repair-deficient mice carrying a microsatellite-containing transgene.
    Hersh MN; Stambrook PJ; Stringer JR
    Mutat Res; 2002 Aug; 505(1-2):51-62. PubMed ID: 12175905
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
    Tomé S; Holt I; Edelmann W; Morris GE; Munnich A; Pearson CE; Gourdon G
    PLoS Genet; 2009 May; 5(5):e1000482. PubMed ID: 19436705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Disease-associated repeat instability and mismatch repair.
    Schmidt MHM; Pearson CE
    DNA Repair (Amst); 2016 Feb; 38():117-126. PubMed ID: 26774442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diverse effects of individual mismatch repair components on transcription-induced CAG repeat instability in human cells.
    Lin Y; Wilson JH
    DNA Repair (Amst); 2009 Aug; 8(8):878-85. PubMed ID: 19497791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC).
    van der Klift H; Wijnen J; Wagner A; Verkuilen P; Tops C; Otway R; Kohonen-Corish M; Vasen H; Oliani C; Barana D; Moller P; Delozier-Blanchet C; Hutter P; Foulkes W; Lynch H; Burn J; Möslein G; Fodde R
    Genes Chromosomes Cancer; 2005 Oct; 44(2):123-38. PubMed ID: 15942939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts.
    Andrew SE; Xu XS; Baross-Francis A; Narayanan L; Milhausen K; Liskay RM; Jirik FR; Glazer PM
    Carcinogenesis; 2000 Jul; 21(7):1291-5. PubMed ID: 10874005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mismatch repair gene PMS2: disease-causing germline mutations are frequent in patients whose tumors stain negative for PMS2 protein, but paralogous genes obscure mutation detection and interpretation.
    Nakagawa H; Lockman JC; Frankel WL; Hampel H; Steenblock K; Burgart LJ; Thibodeau SN; de la Chapelle A
    Cancer Res; 2004 Jul; 64(14):4721-7. PubMed ID: 15256438
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice.
    Xu XS; Narayanan L; Dunklee B; Liskay RM; Glazer PM
    Cancer Res; 2001 May; 61(9):3775-80. PubMed ID: 11325851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Length of CTG.CAG repeats determines the influence of mismatch repair on genetic instability.
    Parniewski P; Jaworski A; Wells RD; Bowater RP
    J Mol Biol; 2000 Jun; 299(4):865-74. PubMed ID: 10843843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Age-, tissue- and length-dependent bidirectional somatic CAG•CTG repeat instability in an allelic series of R6/2 Huntington disease mice.
    Larson E; Fyfe I; Morton AJ; Monckton DG
    Neurobiol Dis; 2015 Apr; 76():98-111. PubMed ID: 25662336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Truncation of the C-terminus of human MLH1 blocks intracellular stabilization of PMS2 and disrupts DNA mismatch repair.
    Mohd AB; Palama B; Nelson SE; Tomer G; Nguyen M; Huo X; Buermeyer AB
    DNA Repair (Amst); 2006 Mar; 5(3):347-61. PubMed ID: 16338176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability.
    Fortune MT; Vassilopoulos C; Coolbaugh MI; Siciliano MJ; Monckton DG
    Hum Mol Genet; 2000 Feb; 9(3):439-45. PubMed ID: 10655554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
    Goula AV; Berquist BR; Wilson DM; Wheeler VC; Trottier Y; Merienne K
    PLoS Genet; 2009 Dec; 5(12):e1000749. PubMed ID: 19997493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Two opposing effects of mismatch repair on CTG repeat instability in Escherichia coli.
    Schmidt KH; Abbott CM; Leach DR
    Mol Microbiol; 2000 Jan; 35(2):463-71. PubMed ID: 10652107
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.