BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 15200121)

  • 1. Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide.
    Hirose Y; Katayama M; Berger MS; Pieper RO
    J Neurosurg; 2004 Jun; 100(6):1060-5. PubMed ID: 15200121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Akt activation suppresses Chk2-mediated, methylating agent-induced G2 arrest and protects from temozolomide-induced mitotic catastrophe and cellular senescence.
    Hirose Y; Katayama M; Mirzoeva OK; Berger MS; Pieper RO
    Cancer Res; 2005 Jun; 65(11):4861-9. PubMed ID: 15930307
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
    Ohba S; Hirose Y; Kawase T; Sano H
    J Neurooncol; 2009 Dec; 95(3):307-316. PubMed ID: 19517066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity.
    Hirose Y; Kreklau EL; Erickson LC; Berger MS; Pieper RO
    J Neurosurg; 2003 Mar; 98(3):591-8. PubMed ID: 12650433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Cdk inhibitor flavopiridol enhances temozolomide-induced cytotoxicity in human glioma cells.
    Hayashi T; Adachi K; Ohba S; Hirose Y
    J Neurooncol; 2013 Nov; 115(2):169-78. PubMed ID: 23943501
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 effects both the duration of G2/M arrest and the fate of temozolomide-treated human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Mar; 61(5):1957-63. PubMed ID: 11280752
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agents.
    Hirose Y; Katayama M; Stokoe D; Haas-Kogan DA; Berger MS; Pieper RO
    Mol Cell Biol; 2003 Nov; 23(22):8306-15. PubMed ID: 14585987
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells.
    Zhuang D; Liu Y; Mao Y; Gao L; Zhang H; Luan S; Huang F; Li Q
    Int J Cancer; 2012 Jan; 130(2):309-18. PubMed ID: 21328340
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent.
    Chalmers AJ; Ruff EM; Martindale C; Lovegrove N; Short SC
    Int J Radiat Oncol Biol Phys; 2009 Dec; 75(5):1511-9. PubMed ID: 19931733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Nadkarni A; Shrivastav M; Mladek AC; Schwingler PM; Grogan PT; Chen J; Sarkaria JN
    J Neurooncol; 2012 Dec; 110(3):349-57. PubMed ID: 23054561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Down-Regulation of AQP4 Expression via p38 MAPK Signaling in Temozolomide-Induced Glioma Cells Growth Inhibition and Invasion Impairment.
    Chen Y; Gao F; Jiang R; Liu H; Hou J; Yi Y; Kang L; Liu X; Li Y; Yang M
    J Cell Biochem; 2017 Dec; 118(12):4905-4913. PubMed ID: 28569417
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of JNK potentiates temozolomide-induced cytotoxicity in U87MG glioblastoma cells via suppression of Akt phosphorylation.
    Vo VA; Lee JW; Lee HJ; Chun W; Lim SY; Kim SS
    Anticancer Res; 2014 Oct; 34(10):5509-15. PubMed ID: 25275048
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lidamycin induces marked G2 cell cycle arrest in human colon carcinoma HT-29 cells through activation of p38 MAPK pathway.
    Liu X; Bian C; Ren K; Jin H; Li B; Shao RG
    Oncol Rep; 2007 Mar; 17(3):597-603. PubMed ID: 17273739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death.
    Chen PH; Cheng CH; Shih CM; Ho KH; Lin CW; Lee CC; Liu AJ; Chang CK; Chen KC
    PLoS One; 2016; 11(11):e0167096. PubMed ID: 27893811
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Resveratrol abrogates the temozolomide-induced G2 arrest leading to mitotic catastrophe and reinforces the temozolomide-induced senescence in glioma cells.
    Filippi-Chiela EC; Thomé MP; Bueno e Silva MM; Pelegrini AL; Ledur PF; Garicochea B; Zamin LL; Lenz G
    BMC Cancer; 2013 Mar; 13():147. PubMed ID: 23522185
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p38 MAPK-dependent Nrf2 induction enhances the resistance of glioma cells against TMZ.
    Ma L; Liu J; Zhang X; Qi J; Yu W; Gu Y
    Med Oncol; 2015 Mar; 32(3):69. PubMed ID: 25691294
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest.
    Yu Q; Liu L; Wang P; Yao Y; Xue Y; Liu Y
    Cell Cycle; 2017 Jun; 16(11):1085-1092. PubMed ID: 28436750
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
    Tentori L; Portarena I; Torino F; Scerrati M; Navarra P; Graziani G
    Glia; 2002 Oct; 40(1):44-54. PubMed ID: 12237842
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.