BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 15205349)

  • 21. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase.
    Mareya SM; Sorrentino BP; Blakley RL
    Cancer Gene Ther; 1998; 5(4):225-35. PubMed ID: 9694074
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs.
    Schultz RM; Chen VJ; Bewley JR; Roberts EF; Shih C; Dempsey JA
    Semin Oncol; 1999 Apr; 26(2 Suppl 6):68-73. PubMed ID: 10598558
    [TBL] [Abstract][Full Text] [Related]  

  • 23. p53-induced apoptosis occurs in the absence of p14(ARF) in malignant pleural mesothelioma.
    Hopkins-Donaldson S; Belyanskaya LL; Simões-Wüst AP; Sigrist B; Kurtz S; Zangemeister-Wittke U; Stahel R
    Neoplasia; 2006 Jul; 8(7):551-9. PubMed ID: 16867217
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human tumor suppressor ARF impedes S-phase progression independent of p53.
    Yarbrough WG; Bessho M; Zanation A; Bisi JE; Xiong Y
    Cancer Res; 2002 Feb; 62(4):1171-7. PubMed ID: 11861400
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate.
    Fanin R; Banerjee D; Volkenandt M; Waltham M; Li WW; Dicker AP; Schweitzer BI; Bertino JR
    Mol Pharmacol; 1993 Jul; 44(1):13-21. PubMed ID: 8341268
    [TBL] [Abstract][Full Text] [Related]  

  • 26. p16INK4a and p14ARF methylation as a potential biomarker for human bladder cancer.
    Kawamoto K; Enokida H; Gotanda T; Kubo H; Nishiyama K; Kawahara M; Nakagawa M
    Biochem Biophys Res Commun; 2006 Jan; 339(3):790-6. PubMed ID: 16316628
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Deregulation of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in basal cell carcinoma.
    Kanellou P; Zaravinos A; Zioga M; Spandidos DA
    Br J Dermatol; 2009 Jun; 160(6):1215-21. PubMed ID: 19298278
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Alternative reading frame protein (ARF)-independent function of CARF (collaborator of ARF) involves its interactions with p53: evidence for a novel p53-activation pathway and its negative feedback control.
    Hasan MK; Yaguchi T; Minoda Y; Hirano T; Taira K; Wadhwa R; Kaul SC
    Biochem J; 2004 Jun; 380(Pt 3):605-10. PubMed ID: 15109303
    [TBL] [Abstract][Full Text] [Related]  

  • 29. p14Arf acts as an antagonist of HMGA2 in senescence of mesenchymal stem cells-implications for benign tumorigenesis.
    Markowski DN; Winter N; Meyer F; von Ahsen I; Wenk H; Nolte I; Bullerdiek J
    Genes Chromosomes Cancer; 2011 Jul; 50(7):489-98. PubMed ID: 21456046
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Cancer research: from folate antagonism to molecular targets.
    Bertino JR
    Best Pract Res Clin Haematol; 2009 Dec; 22(4):577-82. PubMed ID: 19959110
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells.
    Rhee MS; Balinska M; Bunni M; Priest DG; Maley GF; Maley F; Galivan J
    Cancer Res; 1990 Jul; 50(13):3979-84. PubMed ID: 2162250
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The co-transfection of p16(INK4a) and p14(ARF) genes into human lung cancer cell line A549 and the effects on cell growth and chemosensitivity.
    Xie QC; Hu YD; Wang LL; Chen ZT; Diao XW; Wang ZX; Guan HJ; Zhu B; Sun JG; Duan YZ; Chen FL; Nian WQ
    Colloids Surf B Biointerfaces; 2005 Dec; 46(3):188-96. PubMed ID: 16337111
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells.
    Marverti G; Ligabue A; Paglietti G; Corona P; Piras S; Vitale G; Guerrieri D; Luciani R; Costi MP; Frassineti C; Moruzzi MS
    Eur J Pharmacol; 2009 Aug; 615(1-3):17-26. PubMed ID: 19446547
    [TBL] [Abstract][Full Text] [Related]  

  • 34. p53-Dependent and -independent functions of the Arf tumor suppressor.
    Sherr CJ; Bertwistle D; DEN Besten W; Kuo ML; Sugimoto M; Tago K; Williams RT; Zindy F; Roussel MF
    Cold Spring Harb Symp Quant Biol; 2005; 70():129-37. PubMed ID: 16869746
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Retroviral coexpression of thymidylate synthase and dihydrofolate reductase confers fluoropyrimidine and antifolate resistance.
    Fantz CR; Shaw D; Moore JG; Spencer HT
    Biochem Biophys Res Commun; 1998 Feb; 243(1):6-12. PubMed ID: 9473470
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design and rationale for novel antifolates.
    Bertino JR; Sobrero A; Mini E; Moroson BA; Cashmore A
    NCI Monogr; 1987; (5):87-91. PubMed ID: 3431593
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cytotoxicity of antifolate inhibitors of thymidylate and purine synthesis to WiDr colonic carcinoma cells.
    Smith SG; Lehman NL; Moran RG
    Cancer Res; 1993 Dec; 53(23):5697-706. PubMed ID: 8242626
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks.
    Wang W; McLeod HL; Cassidy J; Collie-Duguid ES
    Cancer Chemother Pharmacol; 2007 May; 59(6):839-45. PubMed ID: 17119966
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Folate and antifolate pharmacology.
    Kamen B
    Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-30-S18-39. PubMed ID: 9420019
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Antifolate resistance and its circumvention by new analogues.
    Takemura Y; Kobayashi H; Miyachi H
    Hum Cell; 2001 Sep; 14(3):185-202. PubMed ID: 11774738
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.