BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1430 related articles for article (PubMed ID: 15209520)

  • 1. Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
    Wang H; Vath GM; Gleason KJ; Hanna PE; Wagner CR
    Biochemistry; 2004 Jun; 43(25):8234-46. PubMed ID: 15209520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic mechanism of hamster arylamine N-acetyltransferase 2.
    Wang H; Liu L; Hanna PE; Wagner CR
    Biochemistry; 2005 Aug; 44(33):11295-306. PubMed ID: 16101314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2009 Dec; 22(12):1962-74. PubMed ID: 19842618
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects.
    Schneck JL; Villa JP; McDevitt P; McQueney MS; Thrall SH; Meek TD
    Biochemistry; 2008 Aug; 47(33):8697-710. PubMed ID: 18656960
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of amino acids imparting acceptor substrate selectivity to human arylamine acetyltransferases NAT1 and NAT2.
    Goodfellow GH; Dupret JM; Grant DM
    Biochem J; 2000 May; 348 Pt 1(Pt 1):159-66. PubMed ID: 10794727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Irreversible inactivation of arylamine N-acetyltransferases in the presence of N-hydroxy-4-acetylaminobiphenyl: a comparison of human and hamster enzymes.
    Wang H; Wagner CR; Hanna PE
    Chem Res Toxicol; 2005 Feb; 18(2):183-97. PubMed ID: 15720122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arylamine N-acetyltransferases: characterization of the substrate specificities and molecular interactions of environmental arylamines with human NAT1 and NAT2.
    Liu L; Von Vett A; Zhang N; Walters KJ; Wagner CR; Hanna PE
    Chem Res Toxicol; 2007 Sep; 20(9):1300-8. PubMed ID: 17672512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
    Kratzer R; Kavanagh KL; Wilson DK; Nidetzky B
    Biochemistry; 2004 May; 43(17):4944-54. PubMed ID: 15109252
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Affinity alkylation of hamster hepatic arylamine N-acetyltransferases: isolation of a modified cysteine residue.
    Cheon HG; Boteju LW; Hanna PE
    Mol Pharmacol; 1992 Jul; 42(1):82-93. PubMed ID: 1635555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human arylamine N-acetyltransferase 1: in vitro and intracellular inactivation by nitrosoarene metabolites of toxic and carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2008 Oct; 21(10):2005-16. PubMed ID: 18759501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene.
    Guo Z; Wagner CR; Hanna PE
    Chem Res Toxicol; 2004 Mar; 17(3):275-86. PubMed ID: 15025497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.
    Qian J; Khandogin J; West AH; Cook PF
    Biochemistry; 2008 Jul; 47(26):6851-8. PubMed ID: 18533686
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A density functional theory study on the role of His-107 in arylamine N-acetyltransferase 2 acetylation.
    Qiao QA; Yang C; Qu R; Jin Y; Wang M; Zhang Z; Xu Q; Yu Z
    Biophys Chem; 2006 Aug; 122(3):215-20. PubMed ID: 16644091
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190.
    Zhou X; Zhang N; Liu L; Walters KJ; Hanna PE; Wagner CR
    FEBS J; 2009 Dec; 276(23):6928-41. PubMed ID: 19860825
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
    Tai CH; Yoon MY; Kim SK; Rege VD; Nalabolu SR; Kredich NM; Schnackerz KD; Cook PF
    Biochemistry; 1998 Jul; 37(30):10597-604. PubMed ID: 9692949
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The conserved glycine/alanine residue of the active-site loop containing the putative acetylCoA-binding motif is essential for the overall structural integrity of Mesorhizobium loti arylamine N-acetyltransferase 1.
    Atmane N; Dairou J; Flatters D; Martins M; Pluvinage B; Derreumaux P; Dupret JM; Rodrigues-Lima F
    Biochem Biophys Res Commun; 2007 Sep; 361(1):256-62. PubMed ID: 17658468
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemical mechanism of the serine acetyltransferase from Haemophilus influenzae.
    Johnson CM; Huang B; Roderick SL; Cook PF
    Biochemistry; 2004 Dec; 43(49):15534-9. PubMed ID: 15581365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
    Sim E; Lack N; Wang CJ; Long H; Westwood I; Fullam E; Kawamura A
    Toxicology; 2008 Dec; 254(3):170-83. PubMed ID: 18852012
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
    Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
    Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 72.