BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 15210690)

  • 1. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone promotes functional cooperation of Bcl2 and c-Myc through phosphorylation in regulating cell survival and proliferation.
    Jin Z; Gao F; Flagg T; Deng X
    J Biol Chem; 2004 Sep; 279(38):40209-19. PubMed ID: 15210690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nicotinic receptor-mediated activation by the tobacco-specific nitrosamine NNK of a Raf-1/MAP kinase pathway, resulting in phosphorylation of c-myc in human small cell lung carcinoma cells and pulmonary neuroendocrine cells.
    Jull BA; Plummer HK; Schuller HM
    J Cancer Res Clin Oncol; 2001 Dec; 127(12):707-17. PubMed ID: 11768610
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.
    Xu L; Deng X
    J Biol Chem; 2004 Dec; 279(51):53683-90. PubMed ID: 15471877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NNK promotes migration and invasion of lung cancer cells through activation of c-Src/PKCι/FAK loop.
    Shen J; Xu L; Owonikoko TK; Sun SY; Khuri FR; Curran WJ; Deng X
    Cancer Lett; 2012 May; 318(1):106-13. PubMed ID: 22178655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Survival function of protein kinase C{iota} as a novel nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-activated bad kinase.
    Jin Z; Xin M; Deng X
    J Biol Chem; 2005 Apr; 280(16):16045-52. PubMed ID: 15705582
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity.
    Jin Z; May WS; Gao F; Flagg T; Deng X
    J Biol Chem; 2006 May; 281(20):14446-56. PubMed ID: 16554306
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways.
    Shin VY; Jin HC; Ng EK; Yu J; Leung WK; Cho CH; Sung JJ
    Toxicol Appl Pharmacol; 2008 Dec; 233(2):254-61. PubMed ID: 18805435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases.
    Deng X; Ruvolo P; Carr B; May WS
    Proc Natl Acad Sci U S A; 2000 Feb; 97(4):1578-83. PubMed ID: 10677502
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis.
    Mai H; May WS; Gao F; Jin Z; Deng X
    J Biol Chem; 2003 Jan; 278(3):1886-91. PubMed ID: 12421819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tobacco-specific carcinogenic nitrosamines. Ligands for nicotinic acetylcholine receptors in human lung cancer cells.
    Schuller HM; Orloff M
    Biochem Pharmacol; 1998 May; 55(9):1377-84. PubMed ID: 10076528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) enhances invasiveness of lung cancer cells by up-regulating contactin-1 via the alpha7 nicotinic acetylcholine receptor/ERK signaling pathway.
    Hung YH; Hung WC
    Chem Biol Interact; 2009 May; 179(2-3):154-9. PubMed ID: 19027725
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFkappaB activation and cyclin D1 up-regulation.
    Ho YS; Chen CH; Wang YJ; Pestell RG; Albanese C; Chen RJ; Chang MC; Jeng JH; Lin SY; Liang YC; Tseng H; Lee WS; Lin JK; Chu JS; Chen LC; Lee CH; Tso WL; Lai YC; Wu CH
    Toxicol Appl Pharmacol; 2005 Jun; 205(2):133-48. PubMed ID: 15893541
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance.
    Deng X; Kornblau SM; Ruvolo PP; May WS
    J Natl Cancer Inst Monogr; 2001; (28):30-7. PubMed ID: 11158204
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone stimulates proliferation of immortalized human pancreatic duct epithelia through beta-adrenergic transactivation of EGF receptors.
    Askari MD; Tsao MS; Schuller HM
    J Cancer Res Clin Oncol; 2005 Oct; 131(10):639-48. PubMed ID: 16091975
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel role for JNK as a stress-activated Bcl2 kinase.
    Deng X; Xiao L; Lang W; Gao F; Ruvolo P; May WS
    J Biol Chem; 2001 Jun; 276(26):23681-8. PubMed ID: 11323415
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The modulating role of nuclear factor-kappaB in the action of alpha7-nicotinic acetylcholine receptor and cross-talk between 5-lipoxygenase and cyclooxygenase-2 in colon cancer growth induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
    Ye YN; Liu ES; Shin VY; Wu WK; Cho CH
    J Pharmacol Exp Ther; 2004 Oct; 311(1):123-30. PubMed ID: 15161935
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4-Methylnitrosamino-1-3-pyridyl-1-butanone (NNK) promotes lung cancer cell survival by stimulating thromboxane A2 and its receptor.
    Huang RY; Li MY; Hsin MK; Underwood MJ; Ma LT; Mok TS; Warner TD; Chen GG
    Oncogene; 2011 Jan; 30(1):106-16. PubMed ID: 20818420
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells.
    Majidi M; Al-Wadei HA; Takahashi T; Schuller HM
    Cancer Res; 2007 Jul; 67(14):6863-71. PubMed ID: 17638897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. c-Myc potentiates the mitochondrial pathway of apoptosis by acting upstream of apoptosis signal-regulating kinase 1 (Ask1) in the p38 signalling cascade.
    Desbiens KM; Deschesnes RG; Labrie MM; Desfossés Y; Lambert H; Landry J; Bellmann K
    Biochem J; 2003 Jun; 372(Pt 2):631-41. PubMed ID: 12646044
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis.
    Ruvolo PP; Deng X; Carr BK; May WS
    J Biol Chem; 1998 Sep; 273(39):25436-42. PubMed ID: 9738012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.