These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 15214796)

  • 1. Synthesis and antibacterial activity of a novel series of potent DNA gyrase inhibitors. Pyrazole derivatives.
    Tanitame A; Oyamada Y; Ofuji K; Fujimoto M; Iwai N; Hiyama Y; Suzuki K; Ito H; Terauchi H; Kawasaki M; Nagai K; Wachi M; Yamagishi J
    J Med Chem; 2004 Jul; 47(14):3693-6. PubMed ID: 15214796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antibacterial activity of a novel series of DNA gyrase inhibitors: 5-[(E)-2-arylvinyl]pyrazoles.
    Tanitame A; Oyamada Y; Ofuji K; Terauchi H; Kawasaki M; Wachi M; Yamagishi J
    Bioorg Med Chem Lett; 2005 Oct; 15(19):4299-303. PubMed ID: 16087337
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring.
    Tanitame A; Oyamada Y; Ofuji K; Fujimoto M; Suzuki K; Ueda T; Terauchi H; Kawasaki M; Nagai K; Wachi M; Yamagishi J
    Bioorg Med Chem; 2004 Nov; 12(21):5515-24. PubMed ID: 15465328
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity.
    Tanitame A; Oyamada Y; Ofuji K; Kyoya Y; Suzuki K; Ito H; Kawasaki M; Nagai K; Wachi M; Yamagishi J
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2857-62. PubMed ID: 15125947
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Potent DNA gyrase inhibitors; novel 5-vinylpyrazole analogues with Gram-positive antibacterial activity.
    Tanitame A; Oyamada Y; Ofuji K; Suzuki K; Ito H; Kawasaki M; Wachi M; Yamagishi J
    Bioorg Med Chem Lett; 2004 Jun; 14(11):2863-6. PubMed ID: 15125948
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual-targeting properties of the 3-aminopyrrolidyl quinolones, DC-159a and sitafloxacin, against DNA gyrase and topoisomerase IV: contribution to reducing in vitro emergence of quinolone-resistant Streptococcus pneumoniae.
    Okumura R; Hirata T; Onodera Y; Hoshino K; Otani T; Yamamoto T
    J Antimicrob Chemother; 2008 Jul; 62(1):98-104. PubMed ID: 18390884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: synthesis and antibacterial activity.
    East SP; White CB; Barker O; Barker S; Bennett J; Brown D; Boyd EA; Brennan C; Chowdhury C; Collins I; Convers-Reignier E; Dymock BW; Fletcher R; Haydon DJ; Gardiner M; Hatcher S; Ingram P; Lancett P; Mortenson P; Papadopoulos K; Smee C; Thomaides-Brears HB; Tye H; Workman J; Czaplewski LG
    Bioorg Med Chem Lett; 2009 Feb; 19(3):894-9. PubMed ID: 19095445
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivatives.
    Liu XH; Cui P; Song BA; Bhadury PS; Zhu HL; Wang SF
    Bioorg Med Chem; 2008 Apr; 16(7):4075-82. PubMed ID: 18262793
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, and antibacterial activity of novel 4,5-dihydro-1H-pyrazole derivatives as DNA gyrase inhibitors.
    Liu JJ; Sun J; Fang YB; Yang YA; Jiao RH; Zhu HL
    Org Biomol Chem; 2014 Feb; 12(6):998-1008. PubMed ID: 24382549
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
    Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
    Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis.
    Gomez L; Hack MD; Wu J; Wiener JJ; Venkatesan H; Santillán A; Pippel DJ; Mani N; Morrow BJ; Motley ST; Shaw KJ; Wolin R; Grice CA; Jones TK
    Bioorg Med Chem Lett; 2007 May; 17(10):2723-7. PubMed ID: 17368897
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV.
    Manchester JI; Dussault DD; Rose JA; Boriack-Sjodin PA; Uria-Nickelsen M; Ioannidis G; Bist S; Fleming P; Hull KG
    Bioorg Med Chem Lett; 2012 Aug; 22(15):5150-6. PubMed ID: 22814212
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Quercetin diacylglycoside analogues showing dual inhibition of DNA gyrase and topoisomerase IV as novel antibacterial agents.
    Hossion AM; Zamami Y; Kandahary RK; Tsuchiya T; Ogawa W; Iwado A; Sasaki K
    J Med Chem; 2011 Jun; 54(11):3686-703. PubMed ID: 21534606
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, structure and antibacterial activity of new 2-(1-(2-(substituted-phenyl)-5-methyloxazol-4-yl)-3-(2-substitued-phenyl)-4,5-dihydro-1H-pyrazol-5-yl)-7-substitued-1,2,3,4-tetrahydroisoquinoline derivatives.
    Liu XH; Zhu J; Zhou AN; Song BA; Zhu HL; Bai LS; Bhadury PS; Pan CX
    Bioorg Med Chem; 2009 Feb; 17(3):1207-13. PubMed ID: 19147367
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK.
    Seefeld MA; Miller WH; Newlander KA; Burgess WJ; DeWolf WE; Elkins PA; Head MS; Jakas DR; Janson CA; Keller PM; Manley PJ; Moore TD; Payne DJ; Pearson S; Polizzi BJ; Qiu X; Rittenhouse SF; Uzinskas IN; Wallis NG; Huffman WF
    J Med Chem; 2003 Apr; 46(9):1627-35. PubMed ID: 12699381
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antibacterial evaluation of rhodanine-based 5-aryloxy pyrazoles against selected methicillin resistant and quinolone-resistant Staphylococcus aureus (MRSA and QRSA).
    Song MX; Zheng CJ; Deng XQ; Sun LP; Wu Y; Hong L; Li YJ; Liu Y; Wei ZY; Jin MJ; Piao HR
    Eur J Med Chem; 2013 Feb; 60():376-85. PubMed ID: 23314051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms.
    Ellsworth EL; Tran TP; Showalter HD; Sanchez JP; Watson BM; Stier MA; Domagala JM; Gracheck SJ; Joannides ET; Shapiro MA; Dunham SA; Hanna DL; Huband MD; Gage JW; Bronstein JC; Liu JY; Nguyen DQ; Singh R
    J Med Chem; 2006 Nov; 49(22):6435-8. PubMed ID: 17064062
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.
    Charifson PS; Grillot AL; Grossman TH; Parsons JD; Badia M; Bellon S; Deininger DD; Drumm JE; Gross CH; LeTiran A; Liao Y; Mani N; Nicolau DP; Perola E; Ronkin S; Shannon D; Swenson LL; Tang Q; Tessier PR; Tian SK; Trudeau M; Wang T; Wei Y; Zhang H; Stamos D
    J Med Chem; 2008 Sep; 51(17):5243-63. PubMed ID: 18690678
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.
    Wiles JA; Hashimoto A; Thanassi JA; Cheng J; Incarvito CD; Deshpande M; Pucci MJ; Bradbury BJ
    J Med Chem; 2006 Jan; 49(1):39-42. PubMed ID: 16392790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.
    Angehrn P; Buchmann S; Funk C; Goetschi E; Gmuender H; Hebeisen P; Kostrewa D; Link H; Luebbers T; Masciadri R; Nielsen J; Reindl P; Ricklin F; Schmitt-Hoffmann A; Theil FP
    J Med Chem; 2004 Mar; 47(6):1487-513. PubMed ID: 14998336
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.