367 related articles for article (PubMed ID: 15215142)
1. Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.
Mellado E; Garcia-Effron G; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2004 Jul; 48(7):2747-50. PubMed ID: 15215142
[TBL] [Abstract][Full Text] [Related]
2. Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.
Mellado E; Garcia-Effron G; Buitrago MJ; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2005 Jun; 49(6):2536-8. PubMed ID: 15917566
[TBL] [Abstract][Full Text] [Related]
3. A point mutation in the 14alpha-sterol demethylase gene cyp51A contributes to itraconazole resistance in Aspergillus fumigatus.
Diaz-Guerra TM; Mellado E; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2003 Mar; 47(3):1120-4. PubMed ID: 12604551
[TBL] [Abstract][Full Text] [Related]
4. Genotype-phenotype complexity of the TR46/Y121F/T289A cyp51A azole resistance mechanism in Aspergillus fumigatus.
Snelders E; Camps SM; Karawajczyk A; Rijs AJ; Zoll J; Verweij PE; Melchers WJ
Fungal Genet Biol; 2015 Sep; 82():129-35. PubMed ID: 26092193
[TBL] [Abstract][Full Text] [Related]
5. Differences in interactions between azole drugs related to modifications in the 14-alpha sterol demethylase gene (cyp51A) of Aspergillus fumigatus.
Garcia-Effron G; Mellado E; Gomez-Lopez A; Alcazar-Fuoli L; Cuenca-Estrella M; Rodriguez-Tudela JL
Antimicrob Agents Chemother; 2005 May; 49(5):2119-21. PubMed ID: 15855543
[TBL] [Abstract][Full Text] [Related]
6. Three-dimensional models of 14α-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction.
Alcazar-Fuoli L; Cuesta I; Rodriguez-Tudela JL; Cuenca-Estrella M; Sanglard D; Mellado E
Int J Antimicrob Agents; 2011 Nov; 38(5):426-34. PubMed ID: 21871783
[TBL] [Abstract][Full Text] [Related]
7. A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.
Mellado E; Garcia-Effron G; Alcázar-Fuoli L; Melchers WJ; Verweij PE; Cuenca-Estrella M; Rodríguez-Tudela JL
Antimicrob Agents Chemother; 2007 Jun; 51(6):1897-904. PubMed ID: 17371828
[TBL] [Abstract][Full Text] [Related]
8. Isolation of multiple-triazole-resistant Aspergillus fumigatus strains carrying the TR/L98H mutations in the cyp51A gene in India.
Chowdhary A; Kathuria S; Randhawa HS; Gaur SN; Klaassen CH; Meis JF
J Antimicrob Chemother; 2012 Feb; 67(2):362-6. PubMed ID: 22028200
[TBL] [Abstract][Full Text] [Related]
9. Molecular characterisation of cyp51A and cyp51B genes coding for P450 14alpha-lanosterol demethylases A (CYP51Ap) and B (CYP51Bp) from voriconazole-resistant laboratory isolates of Aspergillus flavus.
Krishnan-Natesan S; Chandrasekar PH; Alangaden GJ; Manavathu EK
Int J Antimicrob Agents; 2008 Dec; 32(6):519-24. PubMed ID: 18775650
[TBL] [Abstract][Full Text] [Related]
10. cyp51A-based mechanism of azole resistance in Aspergillus fumigatus: Illustration by a new 3D Structural Model of Aspergillus fumigatus CYP51A protein.
Liu M; Zheng N; Li D; Zheng H; Zhang L; Ge H; Liu W
Med Mycol; 2016 May; 54(4):400-8. PubMed ID: 26768370
[TBL] [Abstract][Full Text] [Related]
11. In Vitro Biochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus.
Warrilow AG; Parker JE; Price CL; Nes WD; Kelly SL; Kelly DE
Antimicrob Agents Chemother; 2015 Dec; 59(12):7771-8. PubMed ID: 26459890
[TBL] [Abstract][Full Text] [Related]
12. Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma.
Chen J; Li H; Li R; Bu D; Wan Z
J Antimicrob Chemother; 2005 Jan; 55(1):31-7. PubMed ID: 15563516
[TBL] [Abstract][Full Text] [Related]
13. Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms.
Garcia-Rubio R; Alcazar-Fuoli L; Monteiro MC; Monzon S; Cuesta I; Pelaez T; Mellado E
Antimicrob Agents Chemother; 2018 Jun; 62(6):. PubMed ID: 29632011
[TBL] [Abstract][Full Text] [Related]
14. Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009.
Bueid A; Howard SJ; Moore CB; Richardson MD; Harrison E; Bowyer P; Denning DW
J Antimicrob Chemother; 2010 Oct; 65(10):2116-8. PubMed ID: 20729241
[TBL] [Abstract][Full Text] [Related]
15. Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae.
Alcazar-Fuoli L; Mellado E; Cuenca-Estrella M; Sanglard D
Med Mycol; 2011 Apr; 49(3):276-84. PubMed ID: 20831364
[TBL] [Abstract][Full Text] [Related]
16. Multiple cyp51A-based mechanisms identified in azole-resistant isolates of Aspergillus fumigatus from China.
Liu M; Zeng R; Zhang L; Li D; Lv G; Shen Y; Zheng H; Zhang Q; Zhao J; Zheng N; Liu W
Antimicrob Agents Chemother; 2015 Jul; 59(7):4321-5. PubMed ID: 25896700
[TBL] [Abstract][Full Text] [Related]
17. Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus.
Paul S; Diekema D; Moye-Rowley WS
Antimicrob Agents Chemother; 2017 May; 61(5):. PubMed ID: 28264842
[TBL] [Abstract][Full Text] [Related]
18. High-level expression of cyp51B in azole-resistant clinical Aspergillus fumigatus isolates.
Buied A; Moore CB; Denning DW; Bowyer P
J Antimicrob Chemother; 2013 Mar; 68(3):512-4. PubMed ID: 23208831
[TBL] [Abstract][Full Text] [Related]
19. In vitro evolution of itraconazole resistance in Aspergillus fumigatus involves multiple mechanisms of resistance.
da Silva Ferreira ME; Capellaro JL; dos Reis Marques E; Malavazi I; Perlin D; Park S; Anderson JB; Colombo AL; Arthington-Skaggs BA; Goldman MH; Goldman GH
Antimicrob Agents Chemother; 2004 Nov; 48(11):4405-13. PubMed ID: 15504870
[TBL] [Abstract][Full Text] [Related]
20. Does farm fungicide use induce azole resistance in Aspergillus fumigatus?
Kano R; Kohata E; Tateishi A; Murayama SY; Hirose D; Shibata Y; Kosuge Y; Inoue H; Kamata H; Hasegawa A
Med Mycol; 2015 Feb; 53(2):174-7. PubMed ID: 25541556
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]