BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 15217613)

  • 21. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
    Madiraju C; Edler MC; Hamel E; Raccor BS; Balachandran R; Zhu G; Giuliano KA; Vogt A; Shin Y; Fournier JH; Fukui Y; Brückner AM; Curran DP; Day BW
    Biochemistry; 2005 Nov; 44(45):15053-63. PubMed ID: 16274252
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R; Baraldi PG; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Sarkar T; Hamel E
    Bioorg Med Chem; 2008 May; 16(10):5367-76. PubMed ID: 18440234
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
    Bhattacharyya B; Panda D; Gupta S; Banerjee M
    Med Res Rev; 2008 Jan; 28(1):155-83. PubMed ID: 17464966
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK; Kuo CC; Wu YS; Chen CT; Coumar MS; Wu JS; Hsieh HP; Chang CY; Jseng HY; Wu MH; Leou JS; Song JS; Chang JY; Lyu PC; Chao YS; Wu SY
    J Med Chem; 2009 Jul; 52(14):4221-33. PubMed ID: 19507860
    [TBL] [Abstract][Full Text] [Related]  

  • 25. SPIKET and COBRA compounds as novel tubulin modulators with potent anticancer activity.
    Uckun FM; Mao C; Jan ST; Huang H; Vassilev AO; Sudbeck EA; Navara CS; Narla RK
    Curr Opin Investig Drugs; 2000 Oct; 1(2):252-6. PubMed ID: 11249582
    [TBL] [Abstract][Full Text] [Related]  

  • 26. High-content analysis of cancer-cell-specific apoptosis and inhibition of in vivo angiogenesis by synthetic (-)-pironetin and analogs.
    Vogt A; McPherson PA; Shen X; Balachandran R; Zhu G; Raccor BS; Nelson SG; Tsang M; Day BW
    Chem Biol Drug Des; 2009 Oct; 74(4):358-68. PubMed ID: 19691472
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin.
    Knox AJ; Price T; Pawlak M; Golfis G; Flood CT; Fayne D; Williams DC; Meegan MJ; Lloyd DG
    J Med Chem; 2009 Apr; 52(8):2177-80. PubMed ID: 19331414
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Theoretical insight into the structural mechanism for the binding of vinblastine with tubulin.
    Chi S; Xie W; Zhang J; Xu S
    J Biomol Struct Dyn; 2015; 33(10):2234-54. PubMed ID: 25588192
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X; Chen X; Piatnitski EL; Kiselyov AS; He HY; Mao Y; Pattaropong V; Yu Y; Kim KH; Kincaid J; Smith L; Wong WC; Lee SP; Milligan DL; Malikzay A; Fleming J; Gerlak J; Deevi D; Doody JF; Chiang HH; Patel SN; Wang Y; Rolser RL; Kussie P; Labelle M; Tuma MC
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5154-9. PubMed ID: 16198562
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification of the Metabolic Profile of the α-Tubulin-Binding Natural Product (-)-Pironetin.
    Coulup SK; Huang DS; Wong HL; Georg GI
    J Med Chem; 2019 Feb; 62(3):1684-1689. PubMed ID: 30693770
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Nguyen TL; McGrath C; Hermone AR; Burnett JC; Zaharevitz DW; Day BW; Wipf P; Hamel E; Gussio R
    J Med Chem; 2005 Sep; 48(19):6107-16. PubMed ID: 16162011
    [TBL] [Abstract][Full Text] [Related]  

  • 32. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
    J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.
    Smith AB; Freeze BS; Lamarche MJ; Hirose T; Brouard I; Xian M; Sundermann KF; Shaw SJ; Burlingame MA; Horwitz SB; Myles DC
    Org Lett; 2005 Jan; 7(2):315-8. PubMed ID: 15646986
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of a class of novel tubulin inhibitors.
    Yi X; Zhong B; Smith KM; Geldenhuys WJ; Feng Y; Pink JJ; Dowlati A; Xu Y; Zhou A; Su B
    J Med Chem; 2012 Apr; 55(7):3425-35. PubMed ID: 22435708
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanism of action of N-phenyl-N'-(2-chloroethyl)ureas in the colchicine-binding site at the interface between alpha- and beta-tubulin.
    Fortin S; Wei L; Moreau E; Labrie P; Petitclerc E; Kotra LP; C-Gaudreault R
    Bioorg Med Chem; 2009 May; 17(10):3690-7. PubMed ID: 19398206
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Prion protein region 23-32 interacts with tubulin and inhibits microtubule assembly.
    Osiecka KM; Nieznanska H; Skowronek KJ; Karolczak J; Schneider G; Nieznanski K
    Proteins; 2009 Nov; 77(2):279-96. PubMed ID: 19422054
    [TBL] [Abstract][Full Text] [Related]  

  • 37. New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.
    Pera B; Barasoain I; Pantazopoulou A; Canales A; Matesanz R; Rodriguez-Salarichs J; García-Fernandez LF; Moneo V; Jiménez-Barbero J; Galmarini CM; Cuevas C; Peñalva MA; Díaz JF; Andreu JM
    ACS Chem Biol; 2013 Sep; 8(9):2084-94. PubMed ID: 23859655
    [TBL] [Abstract][Full Text] [Related]  

  • 38. N-(2,6-dimethoxypyridine-3-yl)-9-methylcarbazole-3-sulfonamide as a novel tubulin ligand against human cancer.
    Wang YM; Hu LX; Liu ZM; You XF; Zhang SH; Qu JR; Li ZR; Li Y; Kong WJ; He HW; Shao RG; Zhang LR; Peng ZG; Boykin DW; Jiang JD
    Clin Cancer Res; 2008 Oct; 14(19):6218-27. PubMed ID: 18829501
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Binding and interaction of dinitroanilines with apicomplexan and kinetoplastid alpha-tubulin.
    Mitra A; Sept D
    J Med Chem; 2006 Aug; 49(17):5226-31. PubMed ID: 16913711
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The discovery of potent antitumor agent C11-deoxypsymberin/irciniastatin A: total synthesis and biology of advanced psymberin analogs.
    Huang X; Shao N; Huryk R; Palani A; Aslanian R; Seidel-Dugan C
    Org Lett; 2009 Feb; 11(4):867-70. PubMed ID: 19199777
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.