BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 15218027)

  • 1. Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling.
    Kirchhofer D; Yao X; Peek M; Eigenbrot C; Lipari MT; Billeci KL; Maun HR; Moran P; Santell L; Wiesmann C; Lazarus RA
    J Biol Chem; 2004 Sep; 279(38):39915-24. PubMed ID: 15218027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist.
    Kirchhofer D; Lipari MT; Santell L; Billeci KL; Maun HR; Sandoval WN; Moran P; Ridgway J; Eigenbrot C; Lazarus RA
    Proc Natl Acad Sci U S A; 2007 Mar; 104(13):5306-11. PubMed ID: 17372204
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric peptide activators of pro-hepatocyte growth factor stimulate Met signaling.
    Landgraf KE; Santell L; Billeci KL; Quan C; Young JC; Maun HR; Kirchhofer D; Lazarus RA
    J Biol Chem; 2010 Dec; 285(51):40362-72. PubMed ID: 20937841
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa.
    Peek M; Moran P; Mendoza N; Wickramasinghe D; Kirchhofer D
    J Biol Chem; 2002 Dec; 277(49):47804-9. PubMed ID: 12372819
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides.
    Landgraf KE; Steffek M; Quan C; Tom J; Yu C; Santell L; Maun HR; Eigenbrot C; Lazarus RA
    Nat Chem Biol; 2014 Jul; 10(7):567-73. PubMed ID: 24859116
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein.
    Carafoli F; Chirgadze DY; Blundell TL; Gherardi E
    FEBS J; 2005 Nov; 272(22):5799-807. PubMed ID: 16279944
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of functional domains in the hepatocyte growth factor and its receptor by molecular engineering.
    Bardelli A; Ponzetto C; Comoglio PM
    J Biotechnol; 1994 Sep; 37(2):109-22. PubMed ID: 7765452
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptor.
    Stamos J; Lazarus RA; Yao X; Kirchhofer D; Wiesmann C
    EMBO J; 2004 Jun; 23(12):2325-35. PubMed ID: 15167892
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A high affinity hepatocyte growth factor-binding site in the immunoglobulin-like region of Met.
    Basilico C; Arnesano A; Galluzzo M; Comoglio PM; Michieli P
    J Biol Chem; 2008 Jul; 283(30):21267-77. PubMed ID: 18495663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis of hepatocyte growth factor/scatter factor and MET signalling.
    Gherardi E; Sandin S; Petoukhov MV; Finch J; Youles ME; Ofverstedt LG; Miguel RN; Blundell TL; Vande Woude GF; Skoglund U; Svergun DI
    Proc Natl Acad Sci U S A; 2006 Mar; 103(11):4046-51. PubMed ID: 16537482
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of macrophage-stimulating protein with its receptor. Residues critical for beta chain binding and evidence for independent alpha chain binding.
    Danilkovitch A; Miller M; Leonard EJ
    J Biol Chem; 1999 Oct; 274(42):29937-43. PubMed ID: 10514476
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Noncompetitive inhibition of hepatocyte growth factor-dependent Met signaling by a phage-derived peptide.
    Tam EM; Runyon ST; Santell L; Quan C; Yao X; Kirchhofer D; Skelton NJ; Lazarus RA
    J Mol Biol; 2009 Jan; 385(1):79-90. PubMed ID: 18973760
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses.
    Matsumoto K; Kataoka H; Date K; Nakamura T
    J Biol Chem; 1998 Sep; 273(36):22913-20. PubMed ID: 9722511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insights into the structure/function of hepatocyte growth factor/scatter factor from studies with individual domains.
    Holmes O; Pillozzi S; Deakin JA; Carafoli F; Kemp L; Butler PJ; Lyon M; Gherardi E
    J Mol Biol; 2007 Mar; 367(2):395-408. PubMed ID: 17258232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.
    Maun HR; Kirchhofer D; Lazarus RA
    Biol Chem; 2010 Aug; 391(8):881-92. PubMed ID: 20536384
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.
    Hartmann G; Naldini L; Weidner KM; Sachs M; Vigna E; Comoglio PM; Birchmeier W
    Proc Natl Acad Sci U S A; 1992 Dec; 89(23):11574-8. PubMed ID: 1280830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis of MET receptor dimerization by the bacterial invasion protein InlB and the HGF/SF splice variant NK1.
    Niemann HH
    Biochim Biophys Acta; 2013 Oct; 1834(10):2195-204. PubMed ID: 23123275
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mode of receptor binding and activation by plasminogen-related growth factors.
    Miller M; Leonard EJ
    FEBS Lett; 1998 Jun; 429(1):1-3. PubMed ID: 9657372
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cells.
    Comoglio PM
    EXS; 1993; 65():131-65. PubMed ID: 8380735
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dissociation of c-Met phosphotyrosine sites in human cells in response to mouse hepatocyte growth factor but not human hepatocyte growth factor: the possible roles of different amino acids in different species.
    Ikebuchi F; Oka K; Mizuno S; Fukuta K; Hayata D; Ohnishi H; Nakamura T
    Cell Biochem Funct; 2013 Jun; 31(4):298-304. PubMed ID: 22996389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.