BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 15225736)

  • 1. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents.
    Kamal A; Srinivas O; Ramulu P; Ramesh G; Kumar PP
    Bioorg Med Chem Lett; 2004 Aug; 14(15):4107-11. PubMed ID: 15225736
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole conjugates with remarkable DNA-binding affinity.
    Kamal A; Ramulu P; Srinivas O; Ramesh G; Kumar PP
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4791-4. PubMed ID: 15324909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity.
    Kamal A; Kumar PP; Sreekanth K; Seshadri BN; Ramulu P
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2594-8. PubMed ID: 18378445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
    Kamal A; Kumar PP; Seshadri BN; Srinivas O; Kumar MS; Sen S; Kurian N; Juvekar AS; Zingde SM
    Bioorg Med Chem; 2008 Apr; 16(7):3895-906. PubMed ID: 18262426
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Solid-phase synthesis of new pyrrolobenzodiazepine-chalcone conjugates: DNA-binding affinity and anticancer activity.
    Kamal A; Shankaraiah N; Prabhakar S; Reddy ChR; Markandeya N; Reddy KL; Devaiah V
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2434-9. PubMed ID: 18325766
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of fluoroquinolone-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
    Kamal A; Devaiah V; Reddy KL; Kumar MS
    Bioorg Med Chem; 2005 Mar; 13(6):2021-9. PubMed ID: 15727856
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents.
    Kamal A; Srinivas O; Ramulu P; Ramesh G; Kumar PP
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3577-81. PubMed ID: 14505674
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dithiocarbamate/piperazine bridged pyrrolobenzodiazepines as DNA-minor groove binders: synthesis, DNA-binding affinity and cytotoxic activity.
    Kamal A; Sreekanth K; Shankaraiah N; Sathish M; Nekkanti S; Srinivasulu V
    Bioorg Chem; 2015 Apr; 59():23-30. PubMed ID: 25665519
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and DNA-binding affinity of A-C8/C-C2 alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
    Kamal A; Ramulu P; Srinivas O; Ramesh G
    Bioorg Med Chem Lett; 2003 Nov; 13(22):3955-8. PubMed ID: 14592483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents.
    Kamal A; Ramesh G; Ramulu P; Srinivas O; Rehana T; Sheelu G
    Bioorg Med Chem Lett; 2003 Oct; 13(20):3451-4. PubMed ID: 14505647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and DNA-binding ability of pyrrolo[2,1-c][1,4]benzodiazepine-azepane conjugates.
    Kamal A; Reddy DR; Reddy PS; Rajendar
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1160-3. PubMed ID: 16361097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines and their conjugates by azido reductive cyclization strategy as potential DNA-binding agents.
    Kamal A; Babu AH; Ramana AV; Ramana KV; Bharathi EV; Kumar MS
    Bioorg Med Chem Lett; 2005 May; 15(10):2621-3. PubMed ID: 15863329
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA-binding antitumor agents: from pyrimido[5,6,1-de]acridines to other intriguing classes of acridine derivatives.
    Antonini I
    Curr Med Chem; 2002 Sep; 9(18):1701-16. PubMed ID: 12171552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
    Kamal A; Shankaraiah N; Devaiah V; Laxma Reddy K; Juvekar A; Sen S; Kurian N; Zingde S
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1468-73. PubMed ID: 18207392
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) C8 cyclic amine conjugates.
    Masterson LA; Croker SJ; Jenkins TC; Howard PW; Thurston DE
    Bioorg Med Chem Lett; 2004 Feb; 14(4):901-4. PubMed ID: 15012990
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers.
    Kamal A; Srinivas O; Ramulu P; Ramesh G; Kumar PP; Kumar MS
    Bioorg Med Chem; 2004 Aug; 12(16):4337-50. PubMed ID: 15265486
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8' ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers.
    Gregson SJ; Howard PW; Gullick DR; Hamaguchi A; Corcoran KE; Brooks NA; Hartley JA; Jenkins TC; Patel S; Guille MJ; Thurston DE
    J Med Chem; 2004 Feb; 47(5):1161-74. PubMed ID: 14971896
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antitumour activity of pyrene-linked pyrrolo [2,1-c]benzodiazepine hybrids.
    Kamal A; Ramesh G; Srinivas O; Ramulu P
    Bioorg Med Chem Lett; 2004 Jan; 14(2):471-4. PubMed ID: 14698184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of A-ring modifications on the DNA-binding behavior and cytotoxicity of pyrrolo[2,1-c][1,4]benzodiazepines.
    Thurston DE; Bose DS; Howard PW; Jenkins TC; Leoni A; Baraldi PG; Guiotto A; Cacciari B; Kelland LR; Foloppe MP; Rault S
    J Med Chem; 1999 Jun; 42(11):1951-64. PubMed ID: 10354403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An asymmetric C8/C8'-tripyrrole-linked sequence-selective pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimer DNA interstrand cross-linking agent spanning 11 DNA base pairs.
    Tiberghien AC; Evans DA; Kiakos K; Martin CR; Hartley JA; Thurston DE; Howard PW
    Bioorg Med Chem Lett; 2008 Mar; 18(6):2073-7. PubMed ID: 18272367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.