These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 15225749)

  • 1. Therapeutic potential of the 2-alkyl and 2-alkylidene-19-nor-(20S)-modified analogs of 1alpha,25-dihydroxyvitamin D3.
    DeLuca HF
    J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):67-73. PubMed ID: 15225749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methyl substitution of the 25-hydroxy group on 2-methylene-19-nor-1alpha,25-dihydroxyvitamin D3 (2MD) reduces potency but allows bone selectivity.
    Grzywacz P; Plum LA; Sicinski RR; Clagett-Dame M; DeLuca HF
    Arch Biochem Biophys; 2007 Apr; 460(2):274-84. PubMed ID: 17094936
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analogs of 1alpha,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: synthesis and biological evaluation of 2-substituted 19-norvitamin D analogs.
    Shimazaki M; Miyamoto Y; Yamamoto K; Yamada S; Takami M; Shinki T; Udagawa N; Shimizu M
    Bioorg Med Chem; 2006 Jul; 14(13):4645-56. PubMed ID: 16513359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective analogs of 1alpha,25-dihydroxyvitamin D3 for the study of specific functions of Vitamin D.
    DeLuca HF; Plum LA; Clagett-Dame M
    J Steroid Biochem Mol Biol; 2007 Mar; 103(3-5):263-8. PubMed ID: 17241781
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.
    Sicinski RR; Prahl JM; Smith CM; DeLuca HF
    J Med Chem; 1998 Nov; 41(23):4662-74. PubMed ID: 9804706
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.
    Plonska-Ocypa K; Sicinski RR; Plum LA; Grzywacz P; Frelek J; Clagett-Dame M; DeLuca HF
    Bioorg Med Chem; 2009 Feb; 17(4):1747-63. PubMed ID: 19167893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biologically active noncalcemic analogs of 1alpha,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl.
    Plum LA; Prahl JM; Ma X; Sicinski RR; Gowlugari S; Clagett-Dame M; DeLuca HF
    Proc Natl Acad Sci U S A; 2004 May; 101(18):6900-4. PubMed ID: 15118084
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.
    Brandi L
    Dan Med Bull; 2008 Nov; 55(4):186-210. PubMed ID: 19232159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations.
    Vanhooke JL; Tadi BP; Benning MM; Plum LA; DeLuca HF
    Arch Biochem Biophys; 2007 Apr; 460(2):161-5. PubMed ID: 17227670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor.
    Grzywacz P; Plum LA; Sicinska W; Sicinski RR; Prahl JM; DeLuca HF
    J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):13-7. PubMed ID: 15225739
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2-Methylene-19-nor-1alpha-hydroxyvitamin D3 analogs inhibit adipocyte differentiation and PPARgamma2 gene transcription.
    Thomson B; Ahrens JM; Ntambi JM; DeLuca HF; Clagett-Dame M
    Arch Biochem Biophys; 2007 Apr; 460(2):192-201. PubMed ID: 17257576
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Removal of the 20-methyl group from 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D(3) (2MD) selectively eliminates bone calcium mobilization activity.
    Barycki R; Sicinski RR; Plum LA; Grzywacz P; Clagett-Dame M; Deluca HF
    Bioorg Med Chem; 2009 Nov; 17(22):7658-69. PubMed ID: 19819702
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A potent analog of 1alpha,25-dihydroxyvitamin D3 selectively induces bone formation.
    Shevde NK; Plum LA; Clagett-Dame M; Yamamoto H; Pike JW; DeLuca HF
    Proc Natl Acad Sci U S A; 2002 Oct; 99(21):13487-91. PubMed ID: 12374862
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activity of 25-hydroxy-2-methylene-vitamin D3 compounds.
    Sibilska I; Sicinski RR; Plum LA; DeLuca HF
    J Steroid Biochem Mol Biol; 2013 Jul; 136():17-22. PubMed ID: 23274116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and Biological Activity of 2-Methylene Analogues of Calcitriol and Related Compounds.
    Sibilska IK; Szybinski M; Sicinski RR; Plum LA; DeLuca HF
    J Med Chem; 2015 Dec; 58(24):9653-62. PubMed ID: 26574921
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2MD, a new anabolic agent for osteoporosis treatment.
    Plum LA; Fitzpatrick LA; Ma X; Binkley NC; Zella JB; Clagett-Dame M; DeLuca HF
    Osteoporos Int; 2006; 17(5):704-15. PubMed ID: 16491322
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The development of a bone- and parathyroid-specific analog of vitamin D: 2-methylene-19-Nor-(20S)-1α,25-dihydroxyvitamin D3.
    Deluca HF
    Bonekey Rep; 2014; 3():514. PubMed ID: 24818006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methyl-introduced A-ring analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and biological evaluation.
    Fujishima T; Tsutsumi R; Negishi Y; Fujii S; Takayama H; Kittaka A; Kurihara M
    Anticancer Res; 2006; 26(4A):2633-6. PubMed ID: 16886673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. c-Fos protein as a target of anti-osteoclastogenic action of vitamin D, and synthesis of new analogs.
    Takasu H; Sugita A; Uchiyama Y; Katagiri N; Okazaki M; Ogata E; Ikeda K
    J Clin Invest; 2006 Feb; 116(2):528-35. PubMed ID: 16424941
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Low-calcemic, highly antiproliferative, 1-difluoromethyl hybrid analogs of the natural hormone 1alpha,25-dihydroxyvitamin D3: design, synthesis, and preliminary biological evaluation.
    Peleg S; Petersen KS; Suh BC; Dolan P; Agoston ES; Kensler TW; Posner GH
    J Med Chem; 2006 Dec; 49(25):7513-7. PubMed ID: 17149880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.