BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 15235103)

  • 21. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.
    Rosato RR; Almenara JA; Grant S
    Cancer Res; 2003 Jul; 63(13):3637-45. PubMed ID: 12839953
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Rosmarinic acid sensitizes cell death through suppression of TNF-alpha-induced NF-kappaB activation and ROS generation in human leukemia U937 cells.
    Moon DO; Kim MO; Lee JD; Choi YH; Kim GY
    Cancer Lett; 2010 Feb; 288(2):183-91. PubMed ID: 19619938
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells.
    Takada Y; Sethi G; Sung B; Aggarwal BB
    Mol Pharmacol; 2008 May; 73(5):1549-57. PubMed ID: 18287248
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nuclear factor-kappaB p65 small interfering RNA or proteasome inhibitor bortezomib sensitizes head and neck squamous cell carcinomas to classic histone deacetylase inhibitors and novel histone deacetylase inhibitor PXD101.
    Duan J; Friedman J; Nottingham L; Chen Z; Ara G; Van Waes C
    Mol Cancer Ther; 2007 Jan; 6(1):37-50. PubMed ID: 17237265
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Histone deacetylase inhibitors promote STI571-mediated apoptosis in STI571-sensitive and -resistant Bcr/Abl+ human myeloid leukemia cells.
    Yu C; Rahmani M; Almenara J; Subler M; Krystal G; Conrad D; Varticovski L; Dent P; Grant S
    Cancer Res; 2003 May; 63(9):2118-26. PubMed ID: 12727828
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells.
    Domingo-Domènech J; Pippa R; Tápia M; Gascón P; Bachs O; Bosch M
    Breast Cancer Res Treat; 2008 Nov; 112(1):53-62. PubMed ID: 18064564
    [TBL] [Abstract][Full Text] [Related]  

  • 27. An intact NF-kappaB pathway is required for histone deacetylase inhibitor-induced G1 arrest and maturation in U937 human myeloid leukemia cells.
    Dai Y; Rahmani M; Grant S
    Cell Cycle; 2003; 2(5):467-72. PubMed ID: 12963846
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571.
    Yu C; Rahmani M; Conrad D; Subler M; Dent P; Grant S
    Blood; 2003 Nov; 102(10):3765-74. PubMed ID: 12893773
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway.
    Yaseen A; Chen S; Hock S; Rosato R; Dent P; Dai Y; Grant S
    Mol Pharmacol; 2012 Dec; 82(6):1030-41. PubMed ID: 22923501
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.
    Yu C; Krystal G; Varticovksi L; McKinstry R; Rahmani M; Dent P; Grant S
    Cancer Res; 2002 Jan; 62(1):188-99. PubMed ID: 11782377
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells.
    Yu C; Krystal G; Dent P; Grant S
    Clin Cancer Res; 2002 Sep; 8(9):2976-84. PubMed ID: 12231544
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Apoptosis induced by trimethyltin chloride in human neuroblastoma cells SY5Y is regulated by a balance and cross-talk between NF-κB and MAPKs signaling pathways.
    Qing Y; Liang Y; Du Q; Fan P; Xu H; Xu Y; Shi N
    Arch Toxicol; 2013 Jul; 87(7):1273-85. PubMed ID: 23423712
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway.
    Rosato RR; Kolla SS; Hock SK; Almenara JA; Patel A; Amin S; Atadja P; Fisher PB; Dent P; Grant S
    J Biol Chem; 2010 Mar; 285(13):10064-10077. PubMed ID: 20065354
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells.
    Rosato RR; Almenara JA; Dai Y; Grant S
    Mol Cancer Ther; 2003 Dec; 2(12):1273-84. PubMed ID: 14707268
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The histone deacetylase inhibitor LAQ824 induces human leukemia cell death through a process involving XIAP down-regulation, oxidative injury, and the acid sphingomyelinase-dependent generation of ceramide.
    Rosato RR; Maggio SC; Almenara JA; Payne SG; Atadja P; Spiegel S; Dent P; Grant S
    Mol Pharmacol; 2006 Jan; 69(1):216-25. PubMed ID: 16189296
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.
    Dai Y; Chen S; Wang L; Pei XY; Funk VL; Kramer LB; Dent P; Grant S
    J Biol Chem; 2011 Sep; 286(39):34036-50. PubMed ID: 21816815
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells.
    Dai Y; Chen S; Kramer LB; Funk VL; Dent P; Grant S
    Clin Cancer Res; 2008 Jan; 14(2):549-58. PubMed ID: 18223231
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Histone deacetylase inhibitors induce growth arrest and apoptosis of HTLV-1-infected T-cells via blockade of signaling by nuclear factor kappaB.
    Nishioka C; Ikezoe T; Yang J; Komatsu N; Bandobashi K; Taniguchi A; Kuwayama Y; Togitani K; Koeffler HP; Taguchi H
    Leuk Res; 2008 Feb; 32(2):287-96. PubMed ID: 17644177
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
    Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
    J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
    Mitchell C; Park MA; Zhang G; Yacoub A; Curiel DT; Fisher PB; Roberts JD; Grant S; Dent P
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3101-12. PubMed ID: 18065490
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.