BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 15236169)

  • 1. Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes.
    Langmann T; Moehle C; Mauerer R; Scharl M; Liebisch G; Zahn A; Stremmel W; Schmitz G
    Gastroenterology; 2004 Jul; 127(1):26-40. PubMed ID: 15236169
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.
    Blokzijl H; Vander Borght S; Bok LI; Libbrecht L; Geuken M; van den Heuvel FA; Dijkstra G; Roskams TA; Moshage H; Jansen PL; Faber KN
    Inflamm Bowel Dis; 2007 Jun; 13(6):710-20. PubMed ID: 17262809
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shear stress activation of nuclear receptor PXR in endothelial detoxification.
    Wang X; Fang X; Zhou J; Chen Z; Zhao B; Xiao L; Liu A; Li YS; Shyy JY; Guan Y; Chien S; Wang N
    Proc Natl Acad Sci U S A; 2013 Aug; 110(32):13174-9. PubMed ID: 23878263
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells.
    Mencarelli A; Migliorati M; Barbanti M; Cipriani S; Palladino G; Distrutti E; Renga B; Fiorucci S
    Biochem Pharmacol; 2010 Dec; 80(11):1700-7. PubMed ID: 20816942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-kappaB target gene expression.
    Shah YM; Ma X; Morimura K; Kim I; Gonzalez FJ
    Am J Physiol Gastrointest Liver Physiol; 2007 Apr; 292(4):G1114-22. PubMed ID: 17170021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
    Tolson AH; Wang H
    Adv Drug Deliv Rev; 2010 Oct; 62(13):1238-49. PubMed ID: 20727377
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel disease.
    Moehle C; Ackermann N; Langmann T; Aslanidis C; Kel A; Kel-Margoulis O; Schmitz-Madry A; Zahn A; Stremmel W; Schmitz G
    J Mol Med (Berl); 2006 Dec; 84(12):1055-66. PubMed ID: 17058067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.
    Maglich JM; Stoltz CM; Goodwin B; Hawkins-Brown D; Moore JT; Kliewer SA
    Mol Pharmacol; 2002 Sep; 62(3):638-46. PubMed ID: 12181440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation.
    Mencarelli A; Distrutti E; Renga B; D'Amore C; Cipriani S; Palladino G; Donini A; Ricci P; Fiorucci S
    PLoS One; 2011; 6(7):e22978. PubMed ID: 21829567
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inflammatory bowel disease alters intestinal bile acid transporter expression.
    Jahnel J; Fickert P; Hauer AC; Högenauer C; Avian A; Trauner M
    Drug Metab Dispos; 2014 Sep; 42(9):1423-31. PubMed ID: 24965812
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alterations in intestinal fatty acid metabolism in inflammatory bowel disease.
    Heimerl S; Moehle C; Zahn A; Boettcher A; Stremmel W; Langmann T; Schmitz G
    Biochim Biophys Acta; 2006 Mar; 1762(3):341-50. PubMed ID: 16439103
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of the PXR gene locus in inflammatory bowel diseases.
    Martínez A; Márquez A; Mendoza J; Taxonera C; Fernández-Arquero M; Díaz-Rubio M; de la Concha EG; Urcelay E
    Inflamm Bowel Dis; 2007 Dec; 13(12):1484-7. PubMed ID: 17828778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.
    Dring MM; Goulding CA; Trimble VI; Keegan D; Ryan AW; Brophy KM; Smyth CM; Keeling PW; O'Donoghue D; O'Sullivan M; O'Morain C; Mahmud N; Wikström AC; Kelleher D; McManus R
    Gastroenterology; 2006 Feb; 130(2):341-8; quiz 592. PubMed ID: 16472590
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Xenobiotic Nuclear Receptors Pregnane X Receptor and Constitutive Androstane Receptor Regulate Antiretroviral Drug Efflux Transporters at the Blood-Testis Barrier.
    Whyte-Allman SK; Hoque MT; Jenabian MA; Routy JP; Bendayan R
    J Pharmacol Exp Ther; 2017 Dec; 363(3):324-335. PubMed ID: 28970358
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB; Leghait J; Lacroix MZ; Lasserre F; Pineau T; Viguié C; Martin PG
    Biochem Pharmacol; 2013 Oct; 86(7):997-1039. PubMed ID: 23962444
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
    Kandel BA; Thomas M; Winter S; Damm G; Seehofer D; Burk O; Schwab M; Zanger UM
    Biochim Biophys Acta; 2016 Sep; 1859(9):1218-1227. PubMed ID: 26994748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver.
    Albermann N; Schmitz-Winnenthal FH; Z'graggen K; Volk C; Hoffmann MM; Haefeli WE; Weiss J
    Biochem Pharmacol; 2005 Sep; 70(6):949-58. PubMed ID: 16054595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.
    Cui JY; Klaassen CD
    Biochim Biophys Acta; 2016 Sep; 1859(9):1198-1217. PubMed ID: 27113289
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alterations in xenobiotic metabolism in the long-lived Little mice.
    Amador-Noguez D; Dean A; Huang W; Setchell K; Moore D; Darlington G
    Aging Cell; 2007 Aug; 6(4):453-70. PubMed ID: 17521389
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genetic profiling defines the xenobiotic gene network controlled by the nuclear receptor pregnane X receptor.
    Rosenfeld JM; Vargas R; Xie W; Evans RM
    Mol Endocrinol; 2003 Jul; 17(7):1268-82. PubMed ID: 12663745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.