BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 15237852)

  • 1. "Allosterism" in the elementary steps of the cytochrome P450 reaction cycle.
    Yoon MY; Campbell AP; Atkins WM
    Drug Metab Rev; 2004 May; 36(2):219-30. PubMed ID: 15237852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NMR studies of ligand binding to P450(eryF) provides insight into the mechanism of cooperativity.
    Roberts AG; Díaz MD; Lampe JN; Shireman LM; Grinstead JS; Dabrowski MJ; Pearson JT; Bowman MK; Atkins WM; Campbell AP
    Biochemistry; 2006 Feb; 45(6):1673-84. PubMed ID: 16460014
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-Michaelis-Menten kinetics in cytochrome P450-catalyzed reactions.
    Atkins WM
    Annu Rev Pharmacol Toxicol; 2005; 45():291-310. PubMed ID: 15832445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Current views on the fundamental mechanisms of cytochrome P450 allosterism.
    Atkins WM
    Expert Opin Drug Metab Toxicol; 2006 Aug; 2(4):573-9. PubMed ID: 16859405
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Time-resolved fluorescence studies of heterotropic ligand binding to cytochrome P450 3A4.
    Lampe JN; Atkins WM
    Biochemistry; 2006 Oct; 45(40):12204-15. PubMed ID: 17014074
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pyrene.pyrene complexes at the active site of cytochrome P450 3A4: evidence for a multiple substrate binding site.
    Dabrowski MJ; Schrag ML; Wienkers LC; Atkins WM
    J Am Chem Soc; 2002 Oct; 124(40):11866-7. PubMed ID: 12358527
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetics and thermodynamics of ligand binding by cytochrome P450 3A4.
    Isin EM; Guengerich FP
    J Biol Chem; 2006 Apr; 281(14):9127-36. PubMed ID: 16467307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple-ligand binding in CYP2A6: probing mechanisms of cytochrome P450 cooperativity by assessing substrate dynamics.
    Harrelson JP; Atkins WM; Nelson SD
    Biochemistry; 2008 Mar; 47(9):2978-88. PubMed ID: 18247580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The thermodynamic landscape of testosterone binding to cytochrome P450 3A4: ligand binding and spin state equilibria.
    Roberts AG; Campbell AP; Atkins WM
    Biochemistry; 2005 Feb; 44(4):1353-66. PubMed ID: 15667229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytochrome P450 structure-function: insights from molecular dynamics simulations.
    Nair PC; McKinnon RA; Miners JO
    Drug Metab Rev; 2016 Aug; 48(3):434-52. PubMed ID: 27167388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential behavior of the sub-sites of cytochrome 450 active site in binding of substrates, and products (implications for coupling/uncoupling).
    Narasimhulu S
    Biochim Biophys Acta; 2007 Mar; 1770(3):360-75. PubMed ID: 17134838
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Is there a toxicological advantage for non-hyperbolic kinetics in cytochrome P450 catalysis? Functional allostery from "distributive catalysis".
    Atkins WM; Lu WD; Cook DL
    J Biol Chem; 2002 Sep; 277(36):33258-66. PubMed ID: 12082118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The substrate binding site of human liver cytochrome P450 2C9: an NMR study.
    Poli-Scaife S; Attias R; Dansette PM; Mansuy D
    Biochemistry; 1997 Oct; 36(42):12672-82. PubMed ID: 9335524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives.
    Shou M; Mei Q; Ettore MW; Dai R; Baillie TA; Rushmore TH
    Biochem J; 1999 Jun; 340 ( Pt 3)(Pt 3):845-53. PubMed ID: 10359672
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enzyme Kinetics of Oxidative Metabolism-Cytochromes P450.
    Korzekwa K
    Methods Mol Biol; 2021; 2342():237-256. PubMed ID: 34272697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multisite kinetic models for CYP3A4: simultaneous activation and inhibition of diazepam and testosterone metabolism.
    Kenworthy KE; Clarke SE; Andrews J; Houston JB
    Drug Metab Dispos; 2001 Dec; 29(12):1644-51. PubMed ID: 11717184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elucidation of distinct ligand binding sites for cytochrome P450 3A4.
    Hosea NA; Miller GP; Guengerich FP
    Biochemistry; 2000 May; 39(20):5929-39. PubMed ID: 10821664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Allosteric modulation of substrate motion in cytochrome P450 3A4-mediated xylene oxidation.
    Childers WK; Harrelson JP
    Biochemistry; 2014 Feb; 53(6):1018-28. PubMed ID: 24476063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structures of cytochrome P450 3A4.
    Scott EE; Halpert JR
    Trends Biochem Sci; 2005 Jan; 30(1):5-7. PubMed ID: 15653318
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Atypical Michaelis-Menten kinetics in cytochrome P450 enzymes: A focus on substrate inhibition.
    Leow JWH; Chan ECY
    Biochem Pharmacol; 2019 Nov; 169():113615. PubMed ID: 31445022
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.