BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 15239662)

  • 1. Sulfonyl-containing aldophosphamide analogues as novel anticancer prodrugs targeted against cyclophosphamide-resistant tumor cell lines.
    Jain M; Fan J; Baturay NZ; Kwon CH
    J Med Chem; 2004 Jul; 47(15):3843-52. PubMed ID: 15239662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sulfonyl-containing nucleoside phosphotriesters and phosphoramidates as novel anticancer prodrugs of 5-fluoro-2'-deoxyuridine 5'-monophosphate (FdUMP).
    Sun YW; Chen KM; Kwon CH
    Mol Pharm; 2006; 3(2):161-73. PubMed ID: 16579645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of sulfonylethyl-containing phosphotriesters of 3'-azido-3'-deoxythymidine as anticancer prodrugs.
    Wang J; Wang YJ; Chen ZS; Kwon CH
    Bioorg Med Chem; 2014 Nov; 22(21):5747-56. PubMed ID: 25440502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and biological evaluation of cyclic and acyclic nitrobenzylphosphoramide mustards for E. coli nitroreductase activation.
    Jiang Y; Han J; Yu C; Vass SO; Searle PF; Browne P; Knox RJ; Hu L
    J Med Chem; 2006 Jul; 49(14):4333-43. PubMed ID: 16821793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of novel androgen-linked phosphoramide mustard prodrugs and growth-inhibitory activity in human breast cancer cells.
    Roth T; Tang W; Eisenbrand G
    Anticancer Drug Des; 1995 Dec; 10(8):655-66. PubMed ID: 8595124
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy.
    Hu L; Yu C; Jiang Y; Han J; Li Z; Browne P; Race PR; Knox RJ; Searle PF; Hyde EI
    J Med Chem; 2003 Nov; 46(23):4818-21. PubMed ID: 14584930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Engel D; Nudelman A; Tarasenko N; Levovich I; Makarovsky I; Sochotnikov S; Tarasenko I; Rephaeli A
    J Med Chem; 2008 Jan; 51(2):314-23. PubMed ID: 18163551
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acyloxymethyl esters of isophosphoramide mustard as new anticancer prodrugs.
    Cytarska J; Misiura K; Filip-Psurska B; Wietrzyk J
    Acta Pol Pharm; 2013; 70(3):481-7. PubMed ID: 23757939
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aldophosphamide acetal diacetate and structural analogues: synthesis and cytotoxicity studies.
    Wang YQ; Farquhar D
    J Med Chem; 1991 Jan; 34(1):197-203. PubMed ID: 1992116
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
    Berry JM; Bradshaw TD; Fichtner I; Ren R; Schwalbe CH; Wells G; Chew EH; Stevens MF; Westwell AD
    J Med Chem; 2005 Jan; 48(2):639-44. PubMed ID: 15658878
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel fluorinated prodrugs for activation by carboxypeptidase G2 showing good in vivo antitumor activity in gene-directed enzyme prodrug therapy.
    Davies LC; Friedlos F; Hedley D; Martin J; Ogilvie LM; Scanlon IJ; Springer CJ
    J Med Chem; 2005 Aug; 48(16):5321-8. PubMed ID: 16078849
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of indolequinone phosphoramidate prodrugs targeted to DT-diaphorase.
    Hernick M; Flader C; Borch RF
    J Med Chem; 2002 Aug; 45(16):3540-8. PubMed ID: 12139465
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Significant differences in biological parameters between prodrugs cleavable by carboxypeptidase G2 that generate 3,5-difluoro-phenol and -aniline nitrogen mustards in gene-directed enzyme prodrug therapy systems.
    Niculescu-Duvaz I; Scanlon I; Niculescu-Duvaz D; Friedlos F; Martin J; Marais R; Springer CJ
    J Med Chem; 2004 May; 47(10):2651-8. PubMed ID: 15115406
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phenylalanyl-aminocyclophosphamides as model prodrugs for proteolytic activation: synthesis, stability, and stereochemical requirements for enzymatic cleavage.
    Jiang Y; Hu L
    Bioorg Med Chem Lett; 2007 Jan; 17(2):517-21. PubMed ID: 17064897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Atwell GJ; Yang S; Pruijn FB; Pullen SM; Hogg A; Patterson AV; Wilson WR; Denny WA
    J Med Chem; 2007 Mar; 50(6):1197-212. PubMed ID: 17326614
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT).
    Misiura K; Szymanowicz D; Kuśnierczyk H; Wietrzyk J; Opolski A
    Acta Biochim Pol; 2002; 49(1):169-76. PubMed ID: 12136937
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.
    Wei L; Shi Q; Bastow KF; Brossi A; Morris-Natschke SL; Nakagawa-Goto K; Wu TS; Pan SL; Teng CM; Lee KH
    J Med Chem; 2007 Jul; 50(15):3674-80. PubMed ID: 17585747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aziridinyldinitrobenzamides: synthesis and structure-activity relationships for activation by E. coli nitroreductase.
    Helsby NA; Atwell GJ; Yang S; Palmer BD; Anderson RF; Pullen SM; Ferry DM; Hogg A; Wilson WR; Denny WA
    J Med Chem; 2004 Jun; 47(12):3295-307. PubMed ID: 15163209
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro optimization of non-small cell lung cancer activity with troxacitabine, L-1,3-dioxolane-cytidine, prodrugs.
    Radi M; Adema AD; Daft JR; Cho JH; Hoebe EK; Alexander LE; Peters GJ; Chu CK
    J Med Chem; 2007 May; 50(9):2249-53. PubMed ID: 17419604
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of nitroheterocyclic carbamate prodrugs for use with nitroreductase-mediated gene-directed enzyme prodrug therapy.
    Hay MP; Anderson RF; Ferry DM; Wilson WR; Denny WA
    J Med Chem; 2003 Dec; 46(25):5533-45. PubMed ID: 14640560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.