250 related articles for article (PubMed ID: 15240571)
1. Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor.
Gupta-Rossi N; Six E; LeBail O; Logeat F; Chastagner P; Olry A; Israël A; Brou C
J Cell Biol; 2004 Jul; 166(1):73-83. PubMed ID: 15240571
[TBL] [Abstract][Full Text] [Related]
2. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments.
LaVoie MJ; Selkoe DJ
J Biol Chem; 2003 Sep; 278(36):34427-37. PubMed ID: 12826675
[TBL] [Abstract][Full Text] [Related]
3. Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes.
Wang J; Brunkan AL; Hecimovic S; Walker E; Goate A
Neurobiol Dis; 2004 Apr; 15(3):654-66. PubMed ID: 15056474
[TBL] [Abstract][Full Text] [Related]
4. Notch and the amyloid precursor protein are cleaved by similar gamma-secretase(s).
Kimberly WT; Esler WP; Ye W; Ostaszewski BL; Gao J; Diehl T; Selkoe DJ; Wolfe MS
Biochemistry; 2003 Jan; 42(1):137-44. PubMed ID: 12515548
[TBL] [Abstract][Full Text] [Related]
5. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase.
Six E; Ndiaye D; Laabi Y; Brou C; Gupta-Rossi N; Israel A; Logeat F
Proc Natl Acad Sci U S A; 2003 Jun; 100(13):7638-43. PubMed ID: 12794186
[TBL] [Abstract][Full Text] [Related]
6. Aph-1 interacts at the cell surface with proteins in the active gamma-secretase complex and membrane-tethered Notch.
Hansson EM; Strömberg K; Bergstedt S; Yu G; Näslund J; Lundkvist J; Lendahl U
J Neurochem; 2005 Mar; 92(5):1010-20. PubMed ID: 15715652
[TBL] [Abstract][Full Text] [Related]
7. Nectin-1alpha, an immunoglobulin-like receptor involved in the formation of synapses, is a substrate for presenilin/gamma-secretase-like cleavage.
Kim DY; Ingano LA; Kovacs DM
J Biol Chem; 2002 Dec; 277(51):49976-81. PubMed ID: 12376527
[TBL] [Abstract][Full Text] [Related]
8. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain.
De Strooper B; Annaert W; Cupers P; Saftig P; Craessaerts K; Mumm JS; Schroeter EH; Schrijvers V; Wolfe MS; Ray WJ; Goate A; Kopan R
Nature; 1999 Apr; 398(6727):518-22. PubMed ID: 10206645
[TBL] [Abstract][Full Text] [Related]
9. Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.
Fukumori A; Okochi M; Tagami S; Jiang J; Itoh N; Nakayama T; Yanagida K; Ishizuka-Katsura Y; Morihara T; Kamino K; Tanaka T; Kudo T; Tanii H; Ikuta A; Haass C; Takeda M
Biochemistry; 2006 Apr; 45(15):4907-14. PubMed ID: 16605258
[TBL] [Abstract][Full Text] [Related]
10. Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function.
Das I; Craig C; Funahashi Y; Jung KM; Kim TW; Byers R; Weng AP; Kutok JL; Aster JC; Kitajewski J
J Biol Chem; 2004 Jul; 279(29):30771-80. PubMed ID: 15123653
[TBL] [Abstract][Full Text] [Related]
11. Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane.
Kaether C; Lammich S; Edbauer D; Ertl M; Rietdorf J; Capell A; Steiner H; Haass C
J Cell Biol; 2002 Aug; 158(3):551-61. PubMed ID: 12147673
[TBL] [Abstract][Full Text] [Related]
12. Endoproteolysis of the ER stress transducer ATF6 in the presence of functionally inactive presenilins.
Steiner H; Winkler E; Shearman MS; Prywes R; Haass C
Neurobiol Dis; 2001 Aug; 8(4):717-22. PubMed ID: 11493036
[TBL] [Abstract][Full Text] [Related]
13. Functional implications of the presenilin dimerization: reconstitution of gamma-secretase activity by assembly of a catalytic site at the dimer interface of two catalytically inactive presenilins.
Cervantes S; Saura CA; Pomares E; Gonzàlez-Duarte R; Marfany G
J Biol Chem; 2004 Aug; 279(35):36519-29. PubMed ID: 15220354
[TBL] [Abstract][Full Text] [Related]
14. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
[TBL] [Abstract][Full Text] [Related]
15. Nicastrin functions as a gamma-secretase-substrate receptor.
Shah S; Lee SF; Tabuchi K; Hao YH; Yu C; LaPlant Q; Ball H; Dann CE; Südhof T; Yu G
Cell; 2005 Aug; 122(3):435-47. PubMed ID: 16096062
[TBL] [Abstract][Full Text] [Related]
16. Linking receptor-mediated endocytosis and cell signaling: evidence for regulated intramembrane proteolysis of megalin in proximal tubule.
Zou Z; Chung B; Nguyen T; Mentone S; Thomson B; Biemesderfer D
J Biol Chem; 2004 Aug; 279(33):34302-10. PubMed ID: 15180987
[TBL] [Abstract][Full Text] [Related]
17. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.
Laudon H; Mathews PM; Karlström H; Bergman A; Farmery MR; Nixon RA; Winblad B; Gandy SE; Lendahl U; Lundkvist J; Näslund J
J Neurochem; 2004 Apr; 89(1):44-53. PubMed ID: 15030388
[TBL] [Abstract][Full Text] [Related]
18. Functional domains in presenilin 1: the Tyr-288 residue controls gamma-secretase activity and endoproteolysis.
Laudon H; Karlström H; Mathews PM; Farmery MR; Gandy SE; Lundkvist J; Lendahl U; Näslund J
J Biol Chem; 2004 Jun; 279(23):23925-32. PubMed ID: 15051718
[TBL] [Abstract][Full Text] [Related]
19. Presenilin function and gamma-secretase activity.
Brunkan AL; Goate AM
J Neurochem; 2005 May; 93(4):769-92. PubMed ID: 15857382
[TBL] [Abstract][Full Text] [Related]
20. Presenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of Notch.
Sastre M; Steiner H; Fuchs K; Capell A; Multhaup G; Condron MM; Teplow DB; Haass C
EMBO Rep; 2001 Sep; 2(9):835-41. PubMed ID: 11520861
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
