BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 15240642)

  • 1. Estrogen to antiestrogen with a single methylene group resulting in an unusual steroidal selective estrogen receptor modulator.
    Zhang JX; Labaree DC; Mor G; Hochberg RB
    J Clin Endocrinol Metab; 2004 Jul; 89(7):3527-35. PubMed ID: 15240642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of B-, C-, and D-ring-substituted estradiol carboxylic acid esters as locally active estrogens.
    Labaree DC; Zhang JX; Harris HA; O'Connor C; Reynolds TY; Hochberg RB
    J Med Chem; 2003 May; 46(10):1886-904. PubMed ID: 12723952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nonpolar and short side chain groups at C-11beta of estradiol result in antiestrogens.
    Zhang JX; Labaree DC; Hochberg RB
    J Med Chem; 2005 Mar; 48(5):1428-47. PubMed ID: 15743187
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Water extract of Er-xian decoction selectively exerts estrogenic activities and interacts with SERMs in estrogen-sensitive tissues.
    Wong KY; Zhou L; Yu W; Poon CC; Xiao H; Chan CO; Mok DK; Wong MS
    J Ethnopharmacol; 2021 Jul; 275():114096. PubMed ID: 33823166
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats.
    Greenberger LM; Annable T; Collins KI; Komm BS; Lyttle CR; Miller CP; Satyaswaroop PG; Zhang Y; Frost P
    Clin Cancer Res; 2001 Oct; 7(10):3166-77. PubMed ID: 11595711
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of 3-phenyl-4-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]- 2H-1-benzopyran-7-ol (CHF 4056), a novel nonsteroidal estrogen agonist/antagonist, on reproductive and nonreproductive tissue.
    Galbiati E; Caruso PL; Amari G; Armani E; Ghirardi S; Delcanale M; Civelli M
    J Pharmacol Exp Ther; 2002 Mar; 300(3):802-9. PubMed ID: 11861784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deoxybenzoins are novel potent selective estrogen receptor modulators.
    Papoutsi Z; Kassi E; Fokialakis N; Mitakou S; Lambrinidis G; Mikros E; Moutsatsou P
    Steroids; 2007 Sep; 72(9-10):693-704. PubMed ID: 17659312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TAS-108, a novel oral steroidal antiestrogenic agent, is a pure antagonist on estrogen receptor alpha and a partial agonist on estrogen receptor beta with low uterotrophic effect.
    Yamamoto Y; Shibata J; Yonekura K; Sato K; Hashimoto A; Aoyagi Y; Wierzba K; Yano S; Asao T; Buzdar AU; Terada T
    Clin Cancer Res; 2005 Jan; 11(1):315-22. PubMed ID: 15671561
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Idoxifene: a novel selective estrogen receptor modulator prevents bone loss and lowers cholesterol levels in ovariectomized rats and decreases uterine weight in intact rats.
    Nuttall ME; Bradbeer JN; Stroup GB; Nadeau DP; Hoffman SJ; Zhao H; Rehm S; Gowen M
    Endocrinology; 1998 Dec; 139(12):5224-34. PubMed ID: 9832463
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective estrogen receptor modulator inhibits osteocyte apoptosis during abrupt estrogen withdrawal: implications for bone quality maintenance.
    Huber C; Collishaw S; Mosley JR; Reeve J; Noble BS
    Calcif Tissue Int; 2007 Aug; 81(2):139-44. PubMed ID: 17638036
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A selective estrogen receptor modulator for the treatment of hot flushes.
    Wallace OB; Lauwers KS; Dodge JA; May SA; Calvin JR; Hinklin R; Bryant HU; Shetler PK; Adrian MD; Geiser AG; Sato M; Burris TP
    J Med Chem; 2006 Feb; 49(3):843-6. PubMed ID: 16451049
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of CP-336,156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus and body composition in rat models.
    Ke HZ; Paralkar VM; Grasser WA; Crawford DT; Qi H; Simmons HA; Pirie CM; Chidsey-Frink KL; Owen TA; Smock SL; Chen HK; Jee WS; Cameron KO; Rosati RL; Brown TA; Dasilva-Jardine P; Thompson DD
    Endocrinology; 1998 Apr; 139(4):2068-76. PubMed ID: 9528995
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity relationships of nonisomerizable derivatives of tamoxifen: importance of hydroxyl group and side chain positioning for biological activity.
    Murphy CS; Parker CJ; McCague R; Jordan VC
    Mol Pharmacol; 1991 Mar; 39(3):421-8. PubMed ID: 2005879
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7.
    Diel P; Olff S; Schmidt S; Michna H
    Planta Med; 2001 Aug; 67(6):510-4. PubMed ID: 11509969
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11 beta-n-alkyl derivatives bearing a terminal electrophilic group: antiestrogenic and cytotoxic properties.
    Lobaccaro C; Pons JF; Duchesne MJ; Auzou G; Pons M; Nique F; Teutsch G; Borgna JL
    J Med Chem; 1997 Jul; 40(14):2217-27. PubMed ID: 9216841
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The terminal substituents of 7α, 6-hexanyl derivatives of estradiol determine their selective estrogen receptor modulator versus agonist activities.
    Hoffman KL; Foster EA; Smith CL
    Steroids; 2012 Apr; 77(5):496-503. PubMed ID: 22326682
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Estradiol-16alpha-carboxylic acid esters as locally active estrogens.
    Labaree DC; Reynolds TY; Hochberg RB
    J Med Chem; 2001 May; 44(11):1802-14. PubMed ID: 11356114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and structure-activity relationships of chromene-derived selective estrogen receptor modulators for treatment of postmenopausal symptoms.
    Jain N; Xu J; Kanojia RM; Du F; Jian-Zhong G; Pacia E; Lai MT; Musto A; Allan G; Reuman M; Li X; Hahn D; Cousineau M; Peng S; Ritchie D; Russell R; Lundeen S; Sui Z
    J Med Chem; 2009 Dec; 52(23):7544-69. PubMed ID: 19366247
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Selective estrogen receptor-beta (SERM-beta) compounds modulate raphe nuclei tryptophan hydroxylase-1 (TPH-1) mRNA expression and cause antidepressant-like effects in the forced swim test.
    Clark JA; Alves S; Gundlah C; Rocha B; Birzin ET; Cai SJ; Flick R; Hayes E; Ho K; Warrier S; Pai L; Yudkovitz J; Fleischer R; Colwell L; Li S; Wilkinson H; Schaeffer J; Wilkening R; Mattingly E; Hammond M; Rohrer SP
    Neuropharmacology; 2012 Nov; 63(6):1051-63. PubMed ID: 22796107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dissection of the molecular mechanism of action of GW5638, a novel estrogen receptor ligand, provides insights into the role of estrogen receptor in bone.
    Willson TM; Norris JD; Wagner BL; Asplin I; Baer P; Brown HR; Jones SA; Henke B; Sauls H; Wolfe S; Morris DC; McDonnell DP
    Endocrinology; 1997 Sep; 138(9):3901-11. PubMed ID: 9275080
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.