BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 15240680)

  • 21. JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.
    Wang LH; Kirken RA; Erwin RA; Yu CR; Farrar WL
    J Immunol; 1999 Apr; 162(7):3897-904. PubMed ID: 10201908
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.
    Nagy ZS; Wang Y; Erwin-Cohen RA; Aradi J; Monia B; Wang LH; Stepkowski SM; Rui H; Kirken RA
    J Leukoc Biol; 2002 Oct; 72(4):819-28. PubMed ID: 12377952
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells.
    Tai Z; Lin Y; He Y; Huang J; Guo J; Yang L; Zhang G; Wang F
    Cell Signal; 2014 Mar; 26(3):619-28. PubMed ID: 24333668
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.
    Rodriguez G; Ross JA; Nagy ZS; Kirken RA
    J Biol Chem; 2013 Mar; 288(10):7137-46. PubMed ID: 23341462
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.
    Kirken RA; Rui H; Malabarba MG; Howard OM; Kawamura M; O'Shea JJ; Farrar WL
    Cytokine; 1995 Oct; 7(7):689-700. PubMed ID: 8580378
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Inhibition of IL-2-induced Jak-STAT signaling by glucocorticoids.
    Bianchi M; Meng C; Ivashkiv LB
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9573-8. PubMed ID: 10920190
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Ligation of RARgamma inhibits proliferation of phytohaemagglutinin-stimulated T-cells via down-regulating JAK3 protein levels.
    Ludányi K; Nagy ZS; Alexa M; Reichert U; Michel S; Fésüs L; Szondy Z
    Immunol Lett; 2005 Apr; 98(1):103-13. PubMed ID: 15790515
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival.
    Chen J; Yu WM; Bunting KD; Qu CK
    Oncogene; 2004 Apr; 23(20):3659-69. PubMed ID: 15116097
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The critical role of SRC homology domain 2-containing tyrosine phosphatase-1 in recombinant human erythropoietin hyporesponsive anemia in chronic hemodialysis patients.
    Akagi S; Ichikawa H; Okada T; Sarai A; Sugimoto T; Morimoto H; Kihara T; Yano A; Nakao K; Nagake Y; Wada J; Makino H
    J Am Soc Nephrol; 2004 Dec; 15(12):3215-24. PubMed ID: 15579525
    [TBL] [Abstract][Full Text] [Related]  

  • 30. TGF-beta inhibits IL-2-induced tyrosine phosphorylation and activation of Jak-1 and Stat 5 in T lymphocytes.
    Bright JJ; Kerr LD; Sriram S
    J Immunol; 1997 Jul; 159(1):175-83. PubMed ID: 9200453
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Constitutive association of JAK1 and STAT5 in pro-B cells is dissolved by interleukin-4-induced tyrosine phosphorylation of both proteins.
    Erhardt I; Lischke A; Sebald W; Friedrich K
    FEBS Lett; 1998 Nov; 439(1-2):71-4. PubMed ID: 9849880
    [TBL] [Abstract][Full Text] [Related]  

  • 32. TGF-beta does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs.
    Sudarshan C; Galon J; Zhou Y; O'Shea JJ
    J Immunol; 1999 Mar; 162(5):2974-81. PubMed ID: 10072548
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Catalytic-dependent and -independent roles of SHP-2 tyrosine phosphatase in interleukin-3 signaling.
    Yu WM; Hawley TS; Hawley RG; Qu CK
    Oncogene; 2003 Sep; 22(38):5995-6004. PubMed ID: 12955078
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3.
    Simoncic PD; Lee-Loy A; Barber DL; Tremblay ML; McGlade CJ
    Curr Biol; 2002 Mar; 12(6):446-53. PubMed ID: 11909529
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Molecular role of TGF-beta, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice.
    Han HS; Jun HS; Utsugi T; Yoon JW
    J Autoimmun; 1997 Jun; 10(3):299-307. PubMed ID: 9218758
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.
    Oakes SA; Candotti F; Johnston JA; Chen YQ; Ryan JJ; Taylor N; Liu X; Hennighausen L; Notarangelo LD; Paul WE; Blaese RM; O'Shea JJ
    Immunity; 1996 Dec; 5(6):605-15. PubMed ID: 8986719
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Convergence of signaling transduced by prolactin (PRL)/cytokine chimeric receptors on PRL-responsive gene transcription.
    Ferrag F; Chiarenza A; Goffin V; Kelly PA
    Mol Endocrinol; 1996 Apr; 10(4):451-60. PubMed ID: 8721989
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines.
    Pathak MK; Yi T
    J Immunol; 2001 Sep; 167(6):3391-7. PubMed ID: 11544330
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.
    Lin JX; Mietz J; Modi WS; John S; Leonard WJ
    J Biol Chem; 1996 May; 271(18):10738-44. PubMed ID: 8631883
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Suppression of STAT5 functions in liver, mammary glands, and T cells in cytokine-inducible SH2-containing protein 1 transgenic mice.
    Matsumoto A; Seki Y; Kubo M; Ohtsuka S; Suzuki A; Hayashi I; Tsuji K; Nakahata T; Okabe M; Yamada S; Yoshimura A
    Mol Cell Biol; 1999 Sep; 19(9):6396-407. PubMed ID: 10454585
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.