BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

383 related articles for article (PubMed ID: 15240872)

  • 1. Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing.
    Mochizuki Y; He J; Kulkarni S; Bessler M; Mason PJ
    Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10756-61. PubMed ID: 15240872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A telomerase component is defective in the human disease dyskeratosis congenita.
    Mitchell JR; Wood E; Collins K
    Nature; 1999 Dec; 402(6761):551-5. PubMed ID: 10591218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.
    Gu BW; Apicella M; Mills J; Fan JM; Reeves DA; French D; Podsakoff GM; Bessler M; Mason PJ
    PLoS One; 2015; 10(5):e0127414. PubMed ID: 25992652
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Severity of X-linked dyskeratosis congenita (DKCX) cellular defects is not directly related to dyskerin (DKC1) activity in ribosomal RNA biogenesis or mRNA translation.
    Thumati NR; Zeng XL; Au HH; Jang CJ; Jan E; Wong JM
    Hum Mutat; 2013 Dec; 34(12):1698-707. PubMed ID: 24115260
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dyskerin: an essential pseudouridine synthase with multifaceted roles in ribosome biogenesis, splicing, and telomere maintenance.
    Garus A; Autexier C
    RNA; 2021 Dec; 27(12):1441-1458. PubMed ID: 34556550
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dyskerin is required for tumor cell growth through mechanisms that are independent of its role in telomerase and only partially related to its function in precursor rRNA processing.
    Alawi F; Lin P
    Mol Carcinog; 2011 May; 50(5):334-45. PubMed ID: 21480387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dyskeratosis congenita: a disorder of defective telomere maintenance?
    Walne AJ; Marrone A; Dokal I
    Int J Hematol; 2005 Oct; 82(3):184-9. PubMed ID: 16207588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The accumulation and not the specific activity of telomerase ribonucleoprotein determines telomere maintenance deficiency in X-linked dyskeratosis congenita.
    Zeng XL; Thumati NR; Fleisig HB; Hukezalie KR; Savage SA; Giri N; Alter BP; Wong JM
    Hum Mol Genet; 2012 Feb; 21(4):721-9. PubMed ID: 22058290
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant dyskerin ends relationship with telomerase.
    Shay JW; Wright WE
    Science; 1999 Dec; 286(5448):2284-5. PubMed ID: 10636790
    [No Abstract]   [Full Text] [Related]  

  • 10. Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
    Rashid R; Liang B; Baker DL; Youssef OA; He Y; Phipps K; Terns RM; Terns MP; Li H
    Mol Cell; 2006 Jan; 21(2):249-60. PubMed ID: 16427014
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dyskeratosis congenita mutations in dyskerin SUMOylation consensus sites lead to impaired telomerase RNA accumulation and telomere defects.
    Brault ME; Lauzon C; Autexier C
    Hum Mol Genet; 2013 Sep; 22(17):3498-507. PubMed ID: 23660516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.
    Machado-Pinilla R; Carrillo J; Manguan-Garcia C; Sastre L; Mentzer A; Gu BW; Mason PJ; Perona R
    Clin Transl Oncol; 2012 Oct; 14(10):755-63. PubMed ID: 22855157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of dyskeratosis congenita mutations in dyskerin, NHP2 and NOP10 on assembly of H/ACA pre-RNPs.
    Trahan C; Martel C; Dragon F
    Hum Mol Genet; 2010 Mar; 19(5):825-36. PubMed ID: 20008900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification.
    Ruggero D; Grisendi S; Piazza F; Rego E; Mari F; Rao PH; Cordon-Cardo C; Pandolfi PP
    Science; 2003 Jan; 299(5604):259-62. PubMed ID: 12522253
    [TBL] [Abstract][Full Text] [Related]  

  • 15. N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation.
    MacNeil DE; Lambert-Lanteigne P; Autexier C
    Nucleic Acids Res; 2019 Jun; 47(10):5368-5380. PubMed ID: 30931479
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita.
    Wong JM; Collins K
    Genes Dev; 2006 Oct; 20(20):2848-58. PubMed ID: 17015423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Slow growth and unstable ribosomal RNA lacking pseudouridine in mouse embryonic fibroblast cells expressing catalytically inactive dyskerin.
    Gu BW; Ge J; Fan JM; Bessler M; Mason PJ
    FEBS Lett; 2013 Jul; 587(14):2112-7. PubMed ID: 23726835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dyskeratosis congenita: the diverse clinical presentation of mutations in the telomerase complex.
    Vulliamy TJ; Dokal I
    Biochimie; 2008 Jan; 90(1):122-30. PubMed ID: 17825470
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dyskeratosis congenita: its link to telomerase and aplastic anaemia.
    Dokal I; Vulliamy T
    Blood Rev; 2003 Dec; 17(4):217-25. PubMed ID: 14556776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stem cells, telomerase and dyskeratosis congenita.
    Mason PJ
    Bioessays; 2003 Feb; 25(2):126-33. PubMed ID: 12539238
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.