BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 15246361)

  • 1. Synthesis and biological evaluation of [11C]talopram and [11C]talsupram: candidate PET ligands for the norepinephrine transporter.
    McConathy J; Owens MJ; Kilts CD; Malveaux EJ; Camp VM; Votaw JR; Nemeroff CB; Goodman MM
    Nucl Med Biol; 2004 Aug; 31(6):705-18. PubMed ID: 15246361
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
    Huang Y; Bae SA; Zhu Z; Guo N; Roth BL; Laruelle M
    J Med Chem; 2005 Apr; 48(7):2559-70. PubMed ID: 15801845
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vivo evaluation of fluorine-18 and iodine-123 labeled 2beta-carbo(2-fluoroethoxy)-3beta-(4'-((Z)-2-iodoethenyl)phenyl)nortropane as a candidate serotonin transporter imaging agent.
    Plisson C; Stehouwer JS; Voll RJ; Howell L; Votaw JR; Owens MJ; Goodman MM
    J Med Chem; 2007 Sep; 50(19):4553-60. PubMed ID: 17705359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
    Chalon S; Tarkiainen J; Garreau L; Hall H; Emond P; Vercouillie J; Farde L; Dasse P; Varnas K; Besnard JC; Halldin C; Guilloteau D
    J Pharmacol Exp Ther; 2003 Jan; 304(1):81-7. PubMed ID: 12490578
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, radiosynthesis, and biological evaluation of carbon-11 and iodine-123 labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-haloethenyl)phenyl]tropanes: candidate radioligands for in vivo imaging of the serotonin transporter.
    Plisson C; McConathy J; Martarello L; Malveaux EJ; Camp VM; Williams L; Votaw JR; Goodman MM
    J Med Chem; 2004 Feb; 47(5):1122-35. PubMed ID: 14971892
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.
    Zhang S; Zhen J; Reith ME; Dutta AK
    J Med Chem; 2005 Jul; 48(15):4962-71. PubMed ID: 16033275
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds.
    Carroll FI; Tyagi S; Blough BE; Kuhar MJ; Navarro HA
    J Med Chem; 2005 Jun; 48(11):3852-7. PubMed ID: 15916437
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram.
    Schou M; Sóvágó J; Pike VW; Gulyás B; Bøgesø KP; Farde L; Halldin C
    Mol Imaging Biol; 2006; 8(1):1-8. PubMed ID: 16322935
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A PET imaging agent with fast kinetics: synthesis and in vivo evaluation of the serotonin transporter ligand [11C]2-[2-dimethylaminomethylphenylthio)]-5-fluorophenylamine ([11C]AFA).
    Huang Y; Narendran R; Bae SA; Erritzoe D; Guo N; Zhu Z; Hwang DR; Laruelle M
    Nucl Med Biol; 2004 Aug; 31(6):727-38. PubMed ID: 15246363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and C-11 labeling of three potent norepinephrine transporter selective ligands ((R)-nisoxetine, lortalamine, and oxaprotiline) for comparative PET studies in baboons.
    Lin KS; Ding YS
    Bioorg Med Chem; 2005 Aug; 13(15):4658-66. PubMed ID: 15914010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.
    Jarkas N; Voll RJ; Williams L; Votaw JR; Owens M; Goodman MM
    J Med Chem; 2008 Jan; 51(2):271-81. PubMed ID: 18085744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and pharmacological evaluation of 3-(3,4-dichlorophenyl)-1-indanamine derivatives as nonselective ligands for biogenic amine transporters.
    Yu H; Kim IJ; Folk JE; Tian X; Rothman RB; Baumann MH; Dersch CM; Flippen-Anderson JL; Parrish D; Jacobson AE; Rice KC
    J Med Chem; 2004 May; 47(10):2624-34. PubMed ID: 15115403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and monoamine transporter binding of 2-(diarylmethoxymethyl)-3 beta-aryltropane derivatives.
    Xu L; Kulkarni SS; Izenwasser S; Katz JL; Kopajtic T; Lomenzo SA; Newman AH; Trudell ML
    J Med Chem; 2004 Mar; 47(7):1676-82. PubMed ID: 15027858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Semi-automated preparation of the dopamine transporter ligand [(18)F]FECNT for human PET imaging studies.
    Voll RJ; McConathy J; Waldrep MS; Crowe RJ; Goodman MM
    Appl Radiat Isot; 2005 Sep; 63(3):353-61. PubMed ID: 15985372
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.
    Boot JR; Brace G; Delatour CL; Dezutter N; Fairhurst J; Findlay J; Gallagher PT; Hoes I; Mahadevan S; Mitchell SN; Rathmell RE; Richards SJ; Simmonds RG; Wallace L; Whatton MA
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5395-9. PubMed ID: 15454233
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potential of [(18)F]beta-CFT-FE (2beta-carbomethoxy-3beta-(4-fluorophenyl)-8-(2-[(18)F]fluoroethyl)nortropane) as a dopamine transporter ligand: A PET study in the conscious monkey brain.
    Harada N; Ohba H; Fukumoto D; Kakiuchi T; Tsukada H
    Synapse; 2004 Oct; 54(1):37-45. PubMed ID: 15300883
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. Positron Emission Tomography.
    Wellsow J; Kovar KA; Machulla HJ
    J Pharm Pharm Sci; 2002; 5(3):245-57. PubMed ID: 12553893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters.
    Jarkas N; Votaw JR; Voll RJ; Williams L; Camp VM; Owens MJ; Purselle DC; Bremner JD; Kilts CD; Nemeroff CB; Goodman MM
    Nucl Med Biol; 2005 Apr; 32(3):211-24. PubMed ID: 15820756
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.
    Jarkas N; McConathy J; Votaw JR; Voll RJ; Malveaux E; Camp VM; Williams L; Goodman RR; Kilts CD; Goodman MM
    Nucl Med Biol; 2005 Jan; 32(1):75-86. PubMed ID: 15691664
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.