BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

73 related articles for article (PubMed ID: 15248604)

  • 1. 1-Substituted beta-carboline-3-carboxylates with high affinities to the benzodiazepine recognition site.
    Bracher F; Hildebrand D; Häberlein H
    Nat Prod Res; 2004 Oct; 18(5):391-6. PubMed ID: 15248604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional modulation of cerebral gamma-aminobutyric acidA receptor/benzodiazepine receptor/chloride ion channel complex with ethyl beta-carboline-3-carboxylate: presence of independent binding site for ethyl beta-carboline-3-carboxylate.
    Taguchi J; Kuriyama K
    J Pharmacol Exp Ther; 1990 May; 253(2):558-66. PubMed ID: 2159999
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423) at wild type and recombinant GABAA receptors.
    Cox ED; Diaz-Arauzo H; Huang Q; Reddy MS; Ma C; Harris B; McKernan R; Skolnick P; Cook JM
    J Med Chem; 1998 Jul; 41(14):2537-52. PubMed ID: 9651158
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Esters of beta-carboline-3-carboxylic acids with alicyclic alcohols--synthesis and benzodiazepine receptor affinity].
    Geldsetzer KH; Schunack W
    Arch Pharm (Weinheim); 1990 Jan; 323(1):9-12. PubMed ID: 1970720
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthetic routes to 4-amino-3-carboxy-beta-carboline derivatives: incidental formation of novel furo[3,4-c]-beta-carbolin-2-ones displaying high affinities for the benzodiazepine receptor.
    Dorey G; Dubois L; Prodo de Carvalho LP; Potier P; Dodd RH
    J Med Chem; 1995 Jan; 38(1):189-98. PubMed ID: 7837230
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beta-carbolines as benzodiazepine receptor ligands II: Synthesis and benzodiazepine receptor affinity of beta-carboline-3-carboxylic acid amides.
    Lippke KP; Müller WE; Schunack WG
    J Pharm Sci; 1985 Jun; 74(6):676-80. PubMed ID: 2991493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
    Allen MS; Hagen TJ; Trudell ML; Codding PW; Skolnick P; Cook JM
    J Med Chem; 1988 Sep; 31(9):1854-61. PubMed ID: 2842507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. beta-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of beta-carboline-3-carboxylic acid.
    Lippke KP; Schunack WG; Wenning W; Müller WE
    J Med Chem; 1983 Apr; 26(4):499-503. PubMed ID: 6300400
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Benzodiazepine and beta-carboline interactions with GABAA receptor-gated chloride channels in mammalian cultured spinal cord neurons.
    Mehta AK; Ticku MK
    J Pharmacol Exp Ther; 1989 May; 249(2):418-23. PubMed ID: 2542529
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Do benzodiazepine receptors play a role in sleep regulation? Studies with the benzodiazepine antagonist, 3-hydroxymethyl-beta-carboline (3-HMC).
    Mendelson WB; Cain M; Cook JM; Paul SM; Skolnick P
    Prog Clin Biol Res; 1982; 90():253-61. PubMed ID: 6287492
    [No Abstract]   [Full Text] [Related]  

  • 11. Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.
    Yin W; Majumder S; Clayton T; Petrou S; VanLinn ML; Namjoshi OA; Ma C; Cromer BA; Roth BL; Platt DM; Cook JM
    Bioorg Med Chem; 2010 Nov; 18(21):7548-64. PubMed ID: 20888240
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beta-carbolines: synthesis and neurochemical and pharmacological actions on brain benzodiazepine receptors.
    Cain M; Weber RW; Guzman F; Cook JM; Barker SA; Rice KC; Crawley JN; Paul SM; Skolnick P
    J Med Chem; 1982 Sep; 25(9):1081-91. PubMed ID: 6127411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of beta-carboline-benzodiazepine hybrid molecules: use of the known structural requirements for benzodiazepine and beta-carboline binding in designing a novel, high-affinity ligand for the benzodiazepine receptor.
    Dodd RH; Ouannès C; Potier MC; Prado de Carvalho L; Rossier J; Potier P
    J Med Chem; 1987 Jul; 30(7):1248-54. PubMed ID: 3037081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and cytotoxic evaluation of 1-carboxamide and 1-amino side chain substituted β-carbolines.
    Ma C; Cao R; Shi B; Zhou X; Ma Q; Sun J; Guo L; Yi W; Chen Z; Song H
    Eur J Med Chem; 2010 Nov; 45(11):5513-9. PubMed ID: 20846759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bidirectional effects of benzodiazepine binding site ligands in the passive avoidance task: differential antagonism by flumazenil and beta-CCt.
    Savić MM; Obradović DI; Ugresić ND; Cook JM; Yin W; Bokonjić DR
    Behav Brain Res; 2005 Mar; 158(2):293-300. PubMed ID: 15698896
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of beta-carbolines with the benzodiazepine receptor. Structure-activity relationships of amide derivatives of beta-carboline and tetrahydro-beta-carboline.
    Locock RA; Baker GB; Micetich RG; Coutts RT; Benderly A
    Prog Neuropsychopharmacol Biol Psychiatry; 1982; 6(4-6):407-10. PubMed ID: 6298886
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 3-Amino-beta-carboline derivatives and the benzodiazepine receptor. Synthesis of a selective antagonist of the sedative action of diazepam.
    Dodd RH; Ouannès C; de Carvalho LP; Valin A; Venault P; Chapouthier G; Rossier J; Potier P
    J Med Chem; 1985 Jun; 28(6):824-8. PubMed ID: 2989520
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural requirements for agonist actions at the benzodiazepine receptor: studies with analogues of 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester.
    Hollinshead SP; Trudell ML; Skolnick P; Cook JM
    J Med Chem; 1990 Mar; 33(3):1062-9. PubMed ID: 1968513
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular structure of 3-(methoxycarbonyl) amino-beta-carboline, a selective antagonist of the sedative effects of diazepam.
    Dodd RH; Ouannès C; Chiaroni A; Riche C; Poissonnet G; Rossier J; Devaux G; Potier P
    Mol Pharmacol; 1987 Jan; 31(1):74-80. PubMed ID: 3027526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thermodynamic changes associated with benzodiazepine and alkyl beta-carboline-3-carboxylate binding to rat brain homogenates.
    Kochman RL; Hirsch JD
    Mol Pharmacol; 1982 Sep; 22(2):335-41. PubMed ID: 6292692
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.