BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 15254082)

  • 1. An attenuated immune response is sufficient to enhance cognition in an Alzheimer's disease mouse model immunized with amyloid-beta derivatives.
    Sigurdsson EM; Knudsen E; Asuni A; Fitzer-Attas C; Sage D; Quartermain D; Goni F; Frangione B; Wisniewski T
    J Neurosci; 2004 Jul; 24(28):6277-82. PubMed ID: 15254082
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antibody response and plasma Abeta1-40 levels in young Microcebus murinus primates immunized with Abeta1-42 and its derivatives.
    Trouche SG; Asuni A; Rouland S; Wisniewski T; Frangione B; Verdier JM; Sigurdsson EM; Mestre-Francés N
    Vaccine; 2009 Feb; 27(7):957-64. PubMed ID: 19114076
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response.
    Maier M; Seabrook TJ; Lazo ND; Jiang L; Das P; Janus C; Lemere CA
    J Neurosci; 2006 May; 26(18):4717-28. PubMed ID: 16672644
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lack of P-glycoprotein Results in Impairment of Removal of Beta-Amyloid and Increased Intraparenchymal Cerebral Amyloid Angiopathy after Active Immunization in a Transgenic Mouse Model of Alzheimer's Disease.
    Bruckmann S; Brenn A; Grube M; Niedrig K; Holtfreter S; von Bohlen und Halbach O; Groschup M; Keller M; Vogelgesang S
    Curr Alzheimer Res; 2017; 14(6):656-667. PubMed ID: 27915995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Vaccination of Alzheimer's model mice with Abeta derivative in alum adjuvant reduces Abeta burden without microhemorrhages.
    Asuni AA; Boutajangout A; Scholtzova H; Knudsen E; Li YS; Quartermain D; Frangione B; Wisniewski T; Sigurdsson EM
    Eur J Neurosci; 2006 Nov; 24(9):2530-42. PubMed ID: 17100841
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MER5101, a novel Aβ1-15:DT conjugate vaccine, generates a robust anti-Aβ antibody response and attenuates Aβ pathology and cognitive deficits in APPswe/PS1ΔE9 transgenic mice.
    Liu B; Frost JL; Sun J; Fu H; Grimes S; Blackburn P; Lemere CA
    J Neurosci; 2013 Apr; 33(16):7027-37. PubMed ID: 23595760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel monoclonal antibody against the N-terminus of Aβ1-42 reduces plaques and improves cognition in a mouse model of Alzheimer's disease.
    Xing HY; Li B; Peng D; Wang CY; Wang GY; Li P; Le YY; Wang JM; Ye G; Chen JH
    PLoS One; 2017; 12(6):e0180076. PubMed ID: 28662102
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Prophylactic Vaccine Based on Pyroglutamate-3 Amyloid β Generates Strong Antibody Response and Rescues Cognitive Decline in Alzheimer's Disease Model Mice.
    Li G; Hu ZW; Chen PG; Sun ZY; Chen YX; Zhao YF; Li YM
    ACS Chem Neurosci; 2017 Mar; 8(3):454-459. PubMed ID: 28292186
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease.
    Matsuo K; Okamoto H; Kawai Y; Quan YS; Kamiyama F; Hirobe S; Okada N; Nakagawa S
    J Neuroimmunol; 2014 Jan; 266(1-2):1-11. PubMed ID: 24315156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition.
    Das P; Murphy MP; Younkin LH; Younkin SG; Golde TE
    Neurobiol Aging; 2001; 22(5):721-7. PubMed ID: 11705631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice.
    Sigurdsson EM; Scholtzova H; Mehta PD; Frangione B; Wisniewski T
    Am J Pathol; 2001 Aug; 159(2):439-47. PubMed ID: 11485902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Active immunization with the peptide epitope vaccine Aβ3-10-KLH induces a Th2-polarized anti-Aβ antibody response and decreases amyloid plaques in APP/PS1 transgenic mice.
    Ding L; Meng Y; Zhang HY; Yin WC; Yan Y; Cao YP
    Neurosci Lett; 2016 Nov; 634():1-6. PubMed ID: 27693663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Active Aβ vaccination fails to enhance amyloid clearance in a mouse model of Alzheimer's disease with Aβ42-driven pathology.
    Nemirovsky A; Shapiro J; Baron R; Kompaniets A; Monsonego A
    J Neuroimmunol; 2012 Jun; 247(1-2):95-9. PubMed ID: 22498096
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tau passive immunization inhibits not only tau but also Aβ pathology.
    Dai CL; Tung YC; Liu F; Gong CX; Iqbal K
    Alzheimers Res Ther; 2017 Jan; 9(1):1. PubMed ID: 28073379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
    Obregon D; Hou H; Bai Y; Nikolic WV; Mori T; Luo D; Zeng J; Ehrhart J; Fernandez F; Morgan D; Giunta B; Town T; Tan J
    Neurobiol Dis; 2008 Feb; 29(2):336-53. PubMed ID: 18055209
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice.
    Das P; Howard V; Loosbrock N; Dickson D; Murphy MP; Golde TE
    J Neurosci; 2003 Sep; 23(24):8532-8. PubMed ID: 13679422
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nasal inoculation of an adenovirus vector encoding 11 tandem repeats of Abeta1-6 upregulates IL-10 expression and reduces amyloid load in a Mo/Hu APPswe PS1dE9 mouse model of Alzheimer's disease.
    Kim HD; Tahara K; Maxwell JA; Lalonde R; Fukuiwa T; Fujihashi K; Van Kampen KR; Kong FK; Tang DC; Fukuchi K
    J Gene Med; 2007 Feb; 9(2):88-98. PubMed ID: 17219449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel Abeta immunogens: is shorter better?
    Lemere CA; Maier M; Peng Y; Jiang L; Seabrook TJ
    Curr Alzheimer Res; 2007 Sep; 4(4):427-36. PubMed ID: 17908047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses.
    Bowers WJ; Mastrangelo MA; Stanley HA; Casey AE; Milo LJ; Federoff HJ
    Neurobiol Aging; 2005 Apr; 26(4):393-407. PubMed ID: 15653168
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model.
    Song Y; Kim HD; Lee MK; Hong IH; Won CK; Bai HW; Lee SS; Lee S; Chung BY; Cho JH
    PLoS One; 2017; 12(1):e0169509. PubMed ID: 28072821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.