BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

740 related articles for article (PubMed ID: 15254222)

  • 1. Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development.
    Ueda T; Watanabe-Fukunaga R; Fukuyama H; Nagata S; Fukunaga R
    Mol Cell Biol; 2004 Aug; 24(15):6539-49. PubMed ID: 15254222
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2.
    Waskiewicz AJ; Flynn A; Proud CG; Cooper JA
    EMBO J; 1997 Apr; 16(8):1909-20. PubMed ID: 9155017
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo.
    Parra-Palau JL; Scheper GC; Harper DE; Proud CG
    Biochem J; 2005 Feb; 385(Pt 3):695-702. PubMed ID: 15487973
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roles of mitogen-activated protein kinase signal-integrating kinases 1 and 2 in oxidant-mediated eIF4E phosphorylation.
    Shenberger JS; Zhang L; Hughlock MK; Ueda T; Watanabe-Fukunaga R; Fukunaga R
    Int J Biochem Cell Biol; 2007; 39(10):1828-42. PubMed ID: 17689282
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells.
    Scheper GC; Morrice NA; Kleijn M; Proud CG
    Mol Cell Biol; 2001 Feb; 21(3):743-54. PubMed ID: 11154262
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NMDA receptor activation results in PKA- and ERK-dependent Mnk1 activation and increased eIF4E phosphorylation in hippocampal area CA1.
    Banko JL; Hou L; Klann E
    J Neurochem; 2004 Oct; 91(2):462-70. PubMed ID: 15447679
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapamycin enhances eIF4E phosphorylation by activating MAP kinase-interacting kinase 2a (Mnk2a).
    Stead RL; Proud CG
    FEBS Lett; 2013 Aug; 587(16):2623-8. PubMed ID: 23831578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E.
    Reiling JH; Doepfner KT; Hafen E; Stocker H
    Curr Biol; 2005 Jan; 15(1):24-30. PubMed ID: 15649360
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E.
    Pyronnet S; Imataka H; Gingras AC; Fukunaga R; Hunter T; Sonenberg N
    EMBO J; 1999 Jan; 18(1):270-9. PubMed ID: 9878069
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
    Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
    Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.
    Shveygert M; Kaiser C; Bradrick SS; Gromeier M
    Mol Cell Biol; 2010 Nov; 30(21):5160-7. PubMed ID: 20823271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Posttranscriptional regulation of TNFalpha expression via eukaryotic initiation factor 4E (eIF4E) phosphorylation in mouse macrophages.
    Andersson K; Sundler R
    Cytokine; 2006 Jan; 33(1):52-7. PubMed ID: 16431125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress.
    Duncan RF; Peterson H; Sevanian A
    Free Radic Biol Med; 2005 Mar; 38(5):631-43. PubMed ID: 15683719
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mnk1 is required for angiotensin II-induced protein synthesis in vascular smooth muscle cells.
    Ishida M; Ishida T; Nakashima H; Miho N; Miyagawa K; Chayama K; Oshima T; Kambe M; Yoshizumi M
    Circ Res; 2003 Dec; 93(12):1218-24. PubMed ID: 14605021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2.
    Knauf U; Tschopp C; Gram H
    Mol Cell Biol; 2001 Aug; 21(16):5500-11. PubMed ID: 11463832
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle.
    Hu SI; Katz M; Chin S; Qi X; Cruz J; Ibebunjo C; Zhao S; Chen A; Glass DJ
    Sci Signal; 2012 Feb; 5(211):ra14. PubMed ID: 22337810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.
    Kjellerup RB; Kragballe K; Iversen L; Johansen C
    Exp Dermatol; 2008 Jun; 17(6):498-504. PubMed ID: 18081851
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development.
    Ueda T; Sasaki M; Elia AJ; Chio II; Hamada K; Fukunaga R; Mak TW
    Proc Natl Acad Sci U S A; 2010 Aug; 107(32):13984-90. PubMed ID: 20679220
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.
    Li Y; Yue P; Deng X; Ueda T; Fukunaga R; Khuri FR; Sun SY
    Neoplasia; 2010 Oct; 12(10):848-55. PubMed ID: 20927323
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of MNK function sensitizes fibroblasts to serum-withdrawal induced apoptosis.
    Chrestensen CA; Eschenroeder A; Ross WG; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Sturgill TW
    Genes Cells; 2007 Oct; 12(10):1133-40. PubMed ID: 17903173
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.