289 related articles for article (PubMed ID: 15254710)
1. Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells.
Menendez JA; Colomer R; Lupu R
Oncol Rep; 2004 Aug; 12(2):411-22. PubMed ID: 15254710
[TBL] [Abstract][Full Text] [Related]
2. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of Fatty Acid Synthase (FASN) synergistically enhances the efficacy of 5-fluorouracil in breast carcinoma cells.
Vazquez-Martin A; Ropero S; Brunet J; Colomer R; Menendez JA
Oncol Rep; 2007 Oct; 18(4):973-80. PubMed ID: 17786362
[TBL] [Abstract][Full Text] [Related]
4. Pharmacological and small interference RNA-mediated inhibition of breast cancer-associated fatty acid synthase (oncogenic antigen-519) synergistically enhances Taxol (paclitaxel)-induced cytotoxicity.
Menendez JA; Vellon L; Colomer R; Lupu R
Int J Cancer; 2005 May; 115(1):19-35. PubMed ID: 15657900
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of tumor-associated fatty acid synthase hyperactivity induces synergistic chemosensitization of HER -2/ neu -overexpressing human breast cancer cells to docetaxel (taxotere).
Menendez JA; Lupu R; Colomer R
Breast Cancer Res Treat; 2004 Mar; 84(2):183-95. PubMed ID: 14999148
[TBL] [Abstract][Full Text] [Related]
6. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
[TBL] [Abstract][Full Text] [Related]
7. Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells.
Menéndez JA; Ropero S; del Barbacid MM; Montero S; Solanas M; Escrich E; Cortés-Funes H; Colomer R
Breast Cancer Res Treat; 2002 Apr; 72(3):203-19. PubMed ID: 12058962
[TBL] [Abstract][Full Text] [Related]
8. Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.
Menendez JA; Ropero S; Lupu R; Colomer R
Oncol Rep; 2004 Jun; 11(6):1241-52. PubMed ID: 15138562
[TBL] [Abstract][Full Text] [Related]
9. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
Menendez JA; Lupu R
Int J Mol Med; 2005 Jan; 15(1):33-40. PubMed ID: 15583825
[TBL] [Abstract][Full Text] [Related]
10. Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene.
Menendez JA; Vellon L; Lupu R
Ann Oncol; 2005 Aug; 16(8):1253-67. PubMed ID: 15870086
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
Menendez JA; Mehmi I; Verma VA; Teng PK; Lupu R
Mol Carcinog; 2004 Nov; 41(3):164-78. PubMed ID: 15390078
[TBL] [Abstract][Full Text] [Related]
12. Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells.
Ho TS; Ho YP; Wong WY; Chi-Ming Chiu L; Wong YS; Eng-Choon Ooi V
Biomed Pharmacother; 2007 Oct; 61(9):578-87. PubMed ID: 17904792
[TBL] [Abstract][Full Text] [Related]
13. Drug interactions and cytotoxic effects of paclitaxel in combination with carboplatin, epirubicin, gemcitabine or vinorelbine in breast cancer cell lines and tumor samples.
Konecny G; Untch M; Slamon D; Beryt M; Kahlert S; Felber M; Langer E; Lude S; Hepp H; Pegram M
Breast Cancer Res Treat; 2001 Jun; 67(3):223-33. PubMed ID: 11561768
[TBL] [Abstract][Full Text] [Related]
14. Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells.
Menéndez JA; del Mar Barbacid M; Montero S; Sevilla E; Escrich E; Solanas M; Cortés-Funes H; Colomer R
Eur J Cancer; 2001 Feb; 37(3):402-13. PubMed ID: 11239764
[TBL] [Abstract][Full Text] [Related]
15. Death receptor-dependent and -independent pathways in anticancer drug-induced apoptosis of breast cancer cells.
Kim R; Tanabe K; Emi M; Uchida Y; Toge T
Oncol Rep; 2003; 10(6):1925-30. PubMed ID: 14534720
[TBL] [Abstract][Full Text] [Related]
16. Characterization and inhibition of fatty acid synthase in pediatric tumor cell lines.
Slade RF; Hunt DA; Pochet MM; Venema VJ; Hennigar RA
Anticancer Res; 2003; 23(2B):1235-43. PubMed ID: 12820377
[TBL] [Abstract][Full Text] [Related]
17. DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes.
Menendez JA; Vellon L; Lupu R
Int J Mol Med; 2006 Dec; 18(6):1081-7. PubMed ID: 17089011
[TBL] [Abstract][Full Text] [Related]
18. Synergism of cytotoxic effects of vinorelbine and paclitaxel in vitro.
Budman DR; Calabro A; Wang LG; Liu XM; Stiel L; Adams LM; Kreis W
Cancer Invest; 2000; 18(8):695-701. PubMed ID: 11107439
[TBL] [Abstract][Full Text] [Related]
19. Fatty acid synthase inhibitor cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis.
Jeong NY; Lee JS; Yoo KS; Oh S; Choe E; Lee HJ; Park BS; Choi YH; Yoo YH
Apoptosis; 2013 Feb; 18(2):226-37. PubMed ID: 23108760
[TBL] [Abstract][Full Text] [Related]
20. Effects of capecitabine and vinorelbine on cell proliferation, metabolism and COX2 and p16 expression in breast cancer cell lines and solid tumour tissues.
Loo WT; Sasano H; Chow LW
Biomed Pharmacother; 2007 Oct; 61(9):596-600. PubMed ID: 17904787
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]