311 related articles for article (PubMed ID: 15256469)
1. Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells.
Honore S; Kamath K; Braguer D; Horwitz SB; Wilson L; Briand C; Jordan MA
Cancer Res; 2004 Jul; 64(14):4957-64. PubMed ID: 15256469
[TBL] [Abstract][Full Text] [Related]
2. Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation.
Honore S; Kamath K; Braguer D; Wilson L; Briand C; Jordan MA
Mol Cancer Ther; 2003 Dec; 2(12):1303-11. PubMed ID: 14707271
[TBL] [Abstract][Full Text] [Related]
3. Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs.
Chen JG; Horwitz SB
Cancer Res; 2002 Apr; 62(7):1935-8. PubMed ID: 11929805
[TBL] [Abstract][Full Text] [Related]
4. Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.
Bröker LE; Huisman C; Ferreira CG; Rodriguez JA; Kruyt FA; Giaccone G
Cancer Res; 2002 Jul; 62(14):4081-8. PubMed ID: 12124345
[TBL] [Abstract][Full Text] [Related]
5. The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
Kowalski RJ; Giannakakou P; Gunasekera SP; Longley RE; Day BW; Hamel E
Mol Pharmacol; 1997 Oct; 52(4):613-22. PubMed ID: 9380024
[TBL] [Abstract][Full Text] [Related]
6. Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin.
Madiraju C; Edler MC; Hamel E; Raccor BS; Balachandran R; Zhu G; Giuliano KA; Vogt A; Shin Y; Fournier JH; Fukui Y; Brückner AM; Curran DP; Day BW
Biochemistry; 2005 Nov; 44(45):15053-63. PubMed ID: 16274252
[TBL] [Abstract][Full Text] [Related]
7. Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
ter Haar E; Kowalski RJ; Hamel E; Lin CM; Longley RE; Gunasekera SP; Rosenkranz HS; Day BW
Biochemistry; 1996 Jan; 35(1):243-50. PubMed ID: 8555181
[TBL] [Abstract][Full Text] [Related]
8. Discodermolide: just another microtubule-stabilizing agent? No! A lesson in synergy.
Giannakakou P; Fojo T
Clin Cancer Res; 2000 May; 6(5):1613-5. PubMed ID: 10815877
[No Abstract] [Full Text] [Related]
9. A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin.
Xia S; Kenesky CS; Rucker PV; Smith AB; Orr GA; Horwitz SB
Biochemistry; 2006 Oct; 45(39):11762-75. PubMed ID: 17002277
[TBL] [Abstract][Full Text] [Related]
10. Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines.
Martello LA; McDaid HM; Regl DL; Yang CP; Meng D; Pettus TR; Kaufman MD; Arimoto H; Danishefsky SJ; Smith AB; Horwitz SB
Clin Cancer Res; 2000 May; 6(5):1978-87. PubMed ID: 10815923
[TBL] [Abstract][Full Text] [Related]
11. Microtubule-damaging agents enhance RASSF1A-induced cell death in lung cancer cell lines.
Whang YM; Park KH; Jung HY; Jo UH; Kim YH
Cancer; 2009 Mar; 115(6):1253-66. PubMed ID: 19156899
[TBL] [Abstract][Full Text] [Related]
12. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
[TBL] [Abstract][Full Text] [Related]
13. A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel.
Dabydeen DA; Florence GJ; Paterson I; Hamel E
Cancer Chemother Pharmacol; 2004 May; 53(5):397-403. PubMed ID: 15060743
[TBL] [Abstract][Full Text] [Related]
14. Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell lung cancer cells.
AbouEl Hassan MA; Braam SR; Kruyt FA
Cancer Gene Ther; 2006 Dec; 13(12):1105-14. PubMed ID: 16841078
[TBL] [Abstract][Full Text] [Related]
15. Suppression of microtubule dynamics by epothilone B is associated with mitotic arrest.
Kamath K; Jordan MA
Cancer Res; 2003 Sep; 63(18):6026-31. PubMed ID: 14522931
[TBL] [Abstract][Full Text] [Related]
16. Discodermolide analogues as the chemical component of combination bacteriolytic therapy.
Smith AB; Freeze BS; LaMarche MJ; Sager J; Kinzler KW; Vogelstein B
Bioorg Med Chem Lett; 2005 Aug; 15(15):3623-6. PubMed ID: 15979874
[TBL] [Abstract][Full Text] [Related]
17. Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide.
Gertsch J; Meier S; Müller M; Altmann KH
Chembiochem; 2009 Jan; 10(1):166-75. PubMed ID: 19058273
[TBL] [Abstract][Full Text] [Related]
18. The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence.
Klein LE; Freeze BS; Smith AB; Horwitz SB
Cell Cycle; 2005 Mar; 4(3):501-7. PubMed ID: 15711127
[TBL] [Abstract][Full Text] [Related]
19. Antiproliferating activity of the mitotic inhibitor pironetin against vindesine- and paclitaxel-resistant human small cell lung cancer H69 cells.
Yoshida M; Matsui Y; Ikarashi Y; Usui T; Osada H; Wakasugi H
Anticancer Res; 2007; 27(2):729-36. PubMed ID: 17465195
[TBL] [Abstract][Full Text] [Related]
20. Antiangiogenic concentrations of paclitaxel induce an increase in microtubule dynamics in endothelial cells but not in cancer cells.
Pasquier E; Honore S; Pourroy B; Jordan MA; Lehmann M; Briand C; Braguer D
Cancer Res; 2005 Mar; 65(6):2433-40. PubMed ID: 15781659
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
