BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 15262980)

  • 1. The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity.
    Boldt HB; Kjaer-Sorensen K; Overgaard MT; Weyer K; Poulsen CB; Sottrup-Jensen L; Conover CA; Giudice LC; Oxvig C
    J Biol Chem; 2004 Sep; 279(37):38525-31. PubMed ID: 15262980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the third module.
    Weyer K; Boldt HB; Poulsen CB; Kjaer-Sorensen K; Gyrup C; Oxvig C
    J Biol Chem; 2007 Apr; 282(15):10988-99. PubMed ID: 17314100
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the proteolytic activity of pregnancy-associated plasma protein-A by targeting substrate exosite binding.
    Mikkelsen JH; Gyrup C; Kristensen P; Overgaard MT; Poulsen CB; Laursen LS; Oxvig C
    J Biol Chem; 2008 Jun; 283(24):16772-80. PubMed ID: 18434323
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis.
    Laursen LS; Overgaard MT; Nielsen CG; Boldt HB; Hopmann KH; Conover CA; Sottrup-Jensen L; Giudice LC; Oxvig C
    Biochem J; 2002 Oct; 367(Pt 1):31-40. PubMed ID: 12241545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. IGF dependent modulation of IGF binding protein (IGFBP) proteolysis by pregnancy-associated plasma protein-A (PAPP-A): multiple PAPP-A-IGFBP interaction sites.
    Gaidamauskas E; Gyrup C; Boldt HB; Schack VR; Overgaard MT; Laursen LS; Oxvig C
    Biochim Biophys Acta; 2013 Mar; 1830(3):2701-9. PubMed ID: 23671931
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats.
    Laursen LS; Overgaard MT; Weyer K; Boldt HB; Ebbesen P; Christiansen M; Sottrup-Jensen L; Giudice LC; Oxvig C
    J Biol Chem; 2002 Dec; 277(49):47225-34. PubMed ID: 12370176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degradation.
    Monget P; Mazerbourg S; Delpuech T; Maurel MC; Manière S; Zapf J; Lalmanach G; Oxvig C; Overgaard MT
    Biol Reprod; 2003 Jan; 68(1):77-86. PubMed ID: 12493698
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Definition, expression, and characterization of a protein domain in the N-terminus of pregnancy-associated plasma protein-A distantly related to the family of laminin G-like modules.
    Boldt HB; Glerup S; Overgaard MT; Sottrup-Jensen L; Oxvig C
    Protein Expr Purif; 2006 Aug; 48(2):261-73. PubMed ID: 16529943
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos.
    Kjaer-Sorensen K; Engholm DH; Jepsen MR; Morch MG; Weyer K; Hefting LL; Skov LL; Laursen LS; Oxvig C
    J Cell Sci; 2014 Dec; 127(Pt 23):5027-37. PubMed ID: 25236600
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of mutated pregnancy-associated plasma protein-a on atherosclerotic lesion development in mice.
    Boldt HB; Bale LK; Resch ZT; Oxvig C; Overgaard MT; Conover CA
    Endocrinology; 2013 Jan; 154(1):246-52. PubMed ID: 23161866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selection of the dominant follicle and insulin-like growth factor (IGF)-binding proteins: evidence that pregnancy-associated plasma protein A contributes to proteolysis of IGF-binding protein 5 in bovine follicular fluid.
    Rivera GM; Fortune JE
    Endocrinology; 2003 Feb; 144(2):437-46. PubMed ID: 12538602
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase.
    Overgaard MT; Boldt HB; Laursen LS; Sottrup-Jensen L; Conover CA; Oxvig C
    J Biol Chem; 2001 Jun; 276(24):21849-53. PubMed ID: 11264294
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Complex of pregnancy-associated plasma protein-A and the proform of eosinophil major basic protein. Disulfide structure and carbohydrate attachment.
    Overgaard MT; Sorensen ES; Stachowiak D; Boldt HB; Kristensen L; Sottrup-Jensen L; Oxvig C
    J Biol Chem; 2003 Jan; 278(4):2106-17. PubMed ID: 12421832
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pregnancy-associated plasma protein-A (PAPP-A) cleaves insulin-like growth factor binding protein (IGFBP)-5 independent of IGF: implications for the mechanism of IGFBP-4 proteolysis by PAPP-A.
    Laursen LS; Overgaard MT; Søe R; Boldt HB; Sottrup-Jensen L; Giudice LC; Conover CA; Oxvig C
    FEBS Lett; 2001 Aug; 504(1-2):36-40. PubMed ID: 11522292
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Studies on regulation of IGF (insulin-like growth factor)-binding protein (IGFBP) 4 proteolysis by pregnancy-associated plasma protein-A (PAPP-A) in cells treated with phorbol ester.
    Sivanandam AS; Mohan S; Kita H; Kapur S; Chen ST; Linkhart TA; Bagi G; Baylink DJ; Qin X
    Biochem J; 2004 Apr; 379(Pt 1):57-64. PubMed ID: 14705967
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of pregnancy-associated plasma protein-A2 in insulin-like growth factor (IGF) binding protein-5 proteolysis during pregnancy: a potential mechanism for increasing IGF bioavailability.
    Yan X; Baxter RC; Firth SM
    J Clin Endocrinol Metab; 2010 Mar; 95(3):1412-20. PubMed ID: 20103653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length.
    DiPrisco B; Kumar A; Kalra B; Savjani GV; Michael Z; Farr O; Papathanasiou AE; Christou H; Mantzoros C
    Metabolism; 2019 Nov; 100():153959. PubMed ID: 31401027
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteolytic degradation of IGF-binding protein (IGFBP)-2 in equine ovarian follicles: involvement of pregnancy-associated plasma protein-A (PAPP-A) and association with dominant but not subordinated follicles.
    Gérard N; Delpuech T; Oxvig C; Overgaard MT; Monget P
    J Endocrinol; 2004 Sep; 182(3):457-66. PubMed ID: 15350187
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of pregnancy associated plasma protein (PAPP)-A during pregnancy in human and mouse.
    Qin X; Sexton C; Byun D; Strong DD; Baylink DJ; Mohan S
    Growth Horm IGF Res; 2002 Oct; 12(5):359-66. PubMed ID: 12213189
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module.
    Weyer K; Overgaard MT; Laursen LS; Nielsen CG; Schmitz A; Christiansen M; Sottrup-Jensen L; Giudice LC; Oxvig C
    Eur J Biochem; 2004 Apr; 271(8):1525-35. PubMed ID: 15066178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.