These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 15265495)

  • 21. Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1).
    Sun D; Wang Z; Di Y; Jaen JC; Labelle M; Ma J; Miao S; Sudom A; Tang L; Tomooka CS; Tu H; Ursu S; Walker N; Yan X; Ye Q; Powers JP
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3513-6. PubMed ID: 18511278
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Active site variability of type 1 11beta-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons.
    Hult M; Shafqat N; Elleby B; Mitschke D; Svensson S; Forsgren M; Barf T; Vallgårda J; Abrahmsen L; Oppermann U
    Mol Cell Endocrinol; 2006 Mar; 248(1-2):26-33. PubMed ID: 16431016
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis, anti-inflammatory, and antioxidant activities of 18beta-glycyrrhetinic acid derivatives as chemical mediators and xanthine oxidase inhibitors.
    Maitraie D; Hung CF; Tu HY; Liou YT; Wei BL; Yang SC; Wang JP; Lin CN
    Bioorg Med Chem; 2009 Apr; 17(7):2785-92. PubMed ID: 19278854
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model.
    Julian LD; Wang Z; Bostick T; Caille S; Choi R; DeGraffenreid M; Di Y; He X; Hungate RW; Jaen JC; Liu J; Monshouwer M; McMinn D; Rew Y; Sudom A; Sun D; Tu H; Ursu S; Walker N; Yan X; Ye Q; Powers JP
    J Med Chem; 2008 Jul; 51(13):3953-60. PubMed ID: 18553955
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
    Su X; Vicker N; Trusselle M; Halem H; Culler MD; Potter BV
    Mol Cell Endocrinol; 2009 Mar; 301(1-2):169-73. PubMed ID: 18775471
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.
    Yeh VS; Kurukulasuriya R; Madar D; Patel JR; Fung S; Monzon K; Chiou W; Wang J; Jacobson P; Sham HL; Link JT
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5408-13. PubMed ID: 16890427
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interactions of oleanane pentacyclic triterpenoids with human organic anion transporting polypeptide 1B1 and 1B3.
    Tian Y; Wang X; Bi Y; Li X; Zhang Y; Yao Y; Zhang M; Xu T; Zhang Y; Gui C; Zhang W; Zhang C; Yu H; Zhang Y
    Toxicol In Vitro; 2024 Jun; 98():105842. PubMed ID: 38761881
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Effects of 11beta-hydroxysteroid dehydrogenase inhibitor on body weight and glucose tolerance in Sprague-Dawley rats fed with a high-fat diet.
    Liu ZJ; Bai J; Wang YC; Yan D; Wang XX
    Zhongguo Dang Dai Er Ke Za Zhi; 2007 Jun; 9(3):183-7. PubMed ID: 17582250
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Hypolipidemic activity of 18beta-glycyrrhetinic acid on streptozotocin-induced diabetic rats.
    Kalaiarasi P; Kaviarasan K; Pugalendi KV
    Eur J Pharmacol; 2009 Jun; 612(1-3):93-7. PubMed ID: 19361497
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The discovery of azepane sulfonamides as potent 11beta-HSD1 inhibitors.
    Neelamkavil SF; Boyle CD; Chackalamannil S; Greenlee WJ; Zhang L; Terracina G
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4563-5. PubMed ID: 19625185
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Ligand-receptor interaction between triterpenoids and the 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2) enzyme predicts their toxic effects against tumorigenic r/m HM-SFME-1 cells.
    Yamaguchi H; Yu T; Noshita T; Kidachi Y; Kamiie K; Yoshida K; Akitaya T; Umetsu H; Ryoyama K
    J Biol Chem; 2011 Oct; 286(42):36888-97. PubMed ID: 21880714
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Pentanol derivatives from basidiomycete Catathelasma imperiale and their 11beta-hydroxysteroid dehydrogenases inhibitory activity.
    Zhang L; Shen Y; Zhu HJ; Wang F; Leng Y; Liu JK
    J Antibiot (Tokyo); 2009 May; 62(5):239-42. PubMed ID: 19329984
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes.
    Liang JY; Wang SM; Chung TH; Yang SH; Wu JC
    Cell Biol Int; 2008 Nov; 32(11):1371-9. PubMed ID: 18789391
    [TBL] [Abstract][Full Text] [Related]  

  • 34. 18beta-glycyrrhetinic acid promotes src interaction with connexin43 in rat cardiomyocytes.
    Chung TH; Wang SM; Chang YC; Chen YL; Wu JC
    J Cell Biochem; 2007 Feb; 100(3):653-64. PubMed ID: 16983688
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2.
    Zou LW; Li YG; Wang P; Zhou K; Hou J; Jin Q; Hao DC; Ge GB; Yang L
    Eur J Med Chem; 2016 Apr; 112():280-288. PubMed ID: 26900660
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.
    Yeh VS; Patel JR; Yong H; Kurukulasuriya R; Fung S; Monzon K; Chiou W; Wang J; Stolarik D; Imade H; Beno D; Brune M; Jacobson P; Sham H; Link JT
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5414-9. PubMed ID: 16899366
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.
    Xiang J; Wan ZK; Li HQ; Ipek M; Binnun E; Nunez J; Chen L; McKew JC; Mansour TS; Xu X; Suri V; Tam M; Xing Y; Li X; Hahm S; Tobin J; Saiah E
    J Med Chem; 2008 Jul; 51(14):4068-71. PubMed ID: 18578516
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.
    Richards S; Sorensen B; Jae HS; Winn M; Chen Y; Wang J; Fung S; Monzon K; Frevert EU; Jacobson P; Sham H; Link JT
    Bioorg Med Chem Lett; 2006 Dec; 16(24):6241-5. PubMed ID: 17000111
    [TBL] [Abstract][Full Text] [Related]  

  • 39. [Expression of 11β-hydroxysteroid dehydrogenase type 2 in lymphoblastic cells and its relationship with glucocorticoid sensitivity].
    Tao Y; Shi JM; Zhang YX; Gao L; Zhan FH
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2011 Feb; 19(1):109-13. PubMed ID: 21362233
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and biological evaluation of sulfonamidooxazoles and beta-keto sulfones: selective inhibitors of 11beta-hydroxysteroid dehydrogenase type I.
    Xiang J; Ipek M; Suri V; Massefski W; Pan N; Ge Y; Tam M; Xing Y; Tobin JF; Xu X; Tam S
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2865-9. PubMed ID: 15911270
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.