367 related articles for article (PubMed ID: 15271983)
1. Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
Salnikow K; Donald SP; Bruick RK; Zhitkovich A; Phang JM; Kasprzak KS
J Biol Chem; 2004 Sep; 279(39):40337-44. PubMed ID: 15271983
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
[TBL] [Abstract][Full Text] [Related]
3. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
[TBL] [Abstract][Full Text] [Related]
4. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
Tanimoto K; Makino Y; Pereira T; Poellinger L
EMBO J; 2000 Aug; 19(16):4298-309. PubMed ID: 10944113
[TBL] [Abstract][Full Text] [Related]
5. The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1 alpha by a von Hippel-Lindau protein-independent mechanism.
Tang TT; Lasky LA
J Biol Chem; 2003 Aug; 278(32):30125-35. PubMed ID: 12761217
[TBL] [Abstract][Full Text] [Related]
6. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
7. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
Maxwell PH; Wiesener MS; Chang GW; Clifford SC; Vaux EC; Cockman ME; Wykoff CC; Pugh CW; Maher ER; Ratcliffe PJ
Nature; 1999 May; 399(6733):271-5. PubMed ID: 10353251
[TBL] [Abstract][Full Text] [Related]
8. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
Pereira T; Zheng X; Ruas JL; Tanimoto K; Poellinger L
J Biol Chem; 2003 Feb; 278(9):6816-23. PubMed ID: 12468553
[TBL] [Abstract][Full Text] [Related]
9. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
Cockman ME; Masson N; Mole DR; Jaakkola P; Chang GW; Clifford SC; Maher ER; Pugh CW; Ratcliffe PJ; Maxwell PH
J Biol Chem; 2000 Aug; 275(33):25733-41. PubMed ID: 10823831
[TBL] [Abstract][Full Text] [Related]
10. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
[TBL] [Abstract][Full Text] [Related]
11. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
[TBL] [Abstract][Full Text] [Related]
12. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
[TBL] [Abstract][Full Text] [Related]
13. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
Martin F; Linden T; Katschinski DM; Oehme F; Flamme I; Mukhopadhyay CK; Eckhardt K; Tröger J; Barth S; Camenisch G; Wenger RH
Blood; 2005 Jun; 105(12):4613-9. PubMed ID: 15741220
[TBL] [Abstract][Full Text] [Related]
14. Activation of hypoxia-induced transcription in normoxia.
Hägg M; Wennström S
Exp Cell Res; 2005 May; 306(1):180-91. PubMed ID: 15878343
[TBL] [Abstract][Full Text] [Related]
15. Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP.
Sang N; Fang J; Srinivas V; Leshchinsky I; Caro J
Mol Cell Biol; 2002 May; 22(9):2984-92. PubMed ID: 11940656
[TBL] [Abstract][Full Text] [Related]
16. OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.
Baek JH; Mahon PC; Oh J; Kelly B; Krishnamachary B; Pearson M; Chan DA; Giaccia AJ; Semenza GL
Mol Cell; 2005 Feb; 17(4):503-12. PubMed ID: 15721254
[TBL] [Abstract][Full Text] [Related]
17. Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.
Pagé EL; Chan DA; Giaccia AJ; Levine M; Richard DE
Mol Biol Cell; 2008 Jan; 19(1):86-94. PubMed ID: 17942596
[TBL] [Abstract][Full Text] [Related]
18. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Epstein AC; Gleadle JM; McNeill LA; Hewitson KS; O'Rourke J; Mole DR; Mukherji M; Metzen E; Wilson MI; Dhanda A; Tian YM; Masson N; Hamilton DL; Jaakkola P; Barstead R; Hodgkin J; Maxwell PH; Pugh CW; Schofield CJ; Ratcliffe PJ
Cell; 2001 Oct; 107(1):43-54. PubMed ID: 11595184
[TBL] [Abstract][Full Text] [Related]
19. Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex.
Mole DR; Pugh CW; Ratcliffe PJ; Maxwell PH
Adv Enzyme Regul; 2002; 42():333-47. PubMed ID: 12123724
[No Abstract] [Full Text] [Related]
20. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation.
Berra E; Richard DE; Gothié E; Pouysségur J
FEBS Lett; 2001 Feb; 491(1-2):85-90. PubMed ID: 11226425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]