260 related articles for article (PubMed ID: 15272853)
1. Efficient 3D database screening for novel HIV-1 IN inhibitors.
Barreca ML; Rao A; De Luca L; Zappalà M; Gurnari C; Monforte P; De Clercq E; Van Maele B; Debyser Z; Witvrouw M; Briggs JM; Chimirri A
J Chem Inf Comput Sci; 2004; 44(4):1450-5. PubMed ID: 15272853
[TBL] [Abstract][Full Text] [Related]
2. Discovery of HIV-1 integrase inhibitors by pharmacophore searching.
Hong H; Neamati N; Wang S; Nicklaus MC; Mazumder A; Zhao H; Burke TR; Pommier Y; Milne GW
J Med Chem; 1997 Mar; 40(6):930-6. PubMed ID: 9083481
[TBL] [Abstract][Full Text] [Related]
3. Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Clement O; Shoemaker R; Sei S; Neamati N
J Med Chem; 2005 Jan; 48(1):111-20. PubMed ID: 15634005
[TBL] [Abstract][Full Text] [Related]
4. Depsides and depsidones as inhibitors of HIV-1 integrase: discovery of novel inhibitors through 3D database searching.
Neamati N; Hong H; Mazumder A; Wang S; Sunder S; Nicklaus MC; Milne GW; Proksa B; Pommier Y
J Med Chem; 1997 Mar; 40(6):942-51. PubMed ID: 9083483
[TBL] [Abstract][Full Text] [Related]
5. HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.
Nicklaus MC; Neamati N; Hong H; Mazumder A; Sunder S; Chen J; Milne GW; Pommier Y
J Med Chem; 1997 Mar; 40(6):920-9. PubMed ID: 9083480
[TBL] [Abstract][Full Text] [Related]
6. Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.
Mugnaini C; Rajamaki S; Tintori C; Corelli F; Massa S; Witvrouw M; Debyser Z; Veljkovic V; Botta M
Bioorg Med Chem Lett; 2007 Oct; 17(19):5370-3. PubMed ID: 17716893
[TBL] [Abstract][Full Text] [Related]
7. Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
Dayam R; Sanchez T; Neamati N
J Med Chem; 2005 Dec; 48(25):8009-15. PubMed ID: 16335925
[TBL] [Abstract][Full Text] [Related]
8. A platform for designing HIV integrase inhibitors. Part 1: 2-hydroxy-3-heteroaryl acrylic acid derivatives as novel HIV integrase inhibitor and modeling of hydrophilic and hydrophobic pharmacophores.
Kawasuji T; Yoshinaga T; Sato A; Yodo M; Fujiwara T; Kiyama R
Bioorg Med Chem; 2006 Dec; 14(24):8430-45. PubMed ID: 17010623
[TBL] [Abstract][Full Text] [Related]
9. Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase.
Ma K; Wang P; Fu W; Wan X; Zhou L; Chu Y; Ye D
Bioorg Med Chem Lett; 2011 Nov; 21(22):6724-7. PubMed ID: 21996518
[TBL] [Abstract][Full Text] [Related]
10. Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery.
Tintori C; Corradi V; Magnani M; Manetti F; Botta M
J Chem Inf Model; 2008 Nov; 48(11):2166-79. PubMed ID: 18942779
[TBL] [Abstract][Full Text] [Related]
11. Novel virtual screening protocol based on the combined use of molecular modeling and electron-ion interaction potential techniques to design HIV-1 integrase inhibitors.
Tintori C; Manetti F; Veljkovic N; Perovic V; Vercammen J; Hayes S; Massa S; Witvrouw M; Debyser Z; Veljkovic V; Botta M
J Chem Inf Model; 2007; 47(4):1536-44. PubMed ID: 17608406
[TBL] [Abstract][Full Text] [Related]
12. Discovery and structure-activity relationship studies of a unique class of HIV-1 integrase inhibitors.
Dayam R; Sanchez T; Neamati N
ChemMedChem; 2006 Feb; 1(2):238-44. PubMed ID: 16892356
[TBL] [Abstract][Full Text] [Related]
13. Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.
Deng J; Kelley JA; Barchi JJ; Sanchez T; Dayam R; Pommier Y; Neamati N
Bioorg Med Chem; 2006 Jun; 14(11):3785-92. PubMed ID: 16460953
[TBL] [Abstract][Full Text] [Related]
14. Discovery of HIV-1 integrase inhibitors: pharmacophore mapping, virtual screening, molecular docking, synthesis, and biological evaluation.
Bhatt H; Patel P; Pannecouque C
Chem Biol Drug Des; 2014 Feb; 83(2):154-66. PubMed ID: 23957390
[TBL] [Abstract][Full Text] [Related]
15. Naphthoxazepine inhibitors of HIV-1 integrase: synthesis and biological evaluation.
Garofalo A; Grande F; Brizzi A; Aiello F; Dayam R; Neamati N
ChemMedChem; 2008 Jun; 3(6):986-90. PubMed ID: 18383063
[TBL] [Abstract][Full Text] [Related]
16. Triketoacid inhibitors of HIV-integrase: a new chemotype useful for probing the integrase pharmacophore.
Walker MA; Johnson T; Ma Z; Banville J; Remillard R; Kim O; Zhang Y; Staab A; Wong H; Torri A; Samanta H; Lin Z; Deminie C; Terry B; Krystal M; Meanwell N
Bioorg Med Chem Lett; 2006 Jun; 16(11):2920-4. PubMed ID: 16546383
[TBL] [Abstract][Full Text] [Related]
17. Pharmacophore-based database mining for probing fragmental drug-likeness of diketo acid analogues.
Bak A; Magdziarz T; Polanski J
SAR QSAR Environ Res; 2012 Jan; 23(1-2):185-204. PubMed ID: 22292781
[TBL] [Abstract][Full Text] [Related]
18. Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75.
De Luca L; Barreca ML; Ferro S; Christ F; Iraci N; Gitto R; Monforte AM; Debyser Z; Chimirri A
ChemMedChem; 2009 Aug; 4(8):1311-6. PubMed ID: 19565598
[TBL] [Abstract][Full Text] [Related]
19. Hydrazide-containing inhibitors of HIV-1 integrase.
Zhao H; Neamati N; Sunder S; Hong H; Wang S; Milne GW; Pommier Y; Burke TR
J Med Chem; 1997 Mar; 40(6):937-41. PubMed ID: 9083482
[TBL] [Abstract][Full Text] [Related]
20. Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.
Barreca ML; Ferro S; Rao A; De Luca L; Zappalà M; Monforte AM; Debyser Z; Witvrouw M; Chimirri A
J Med Chem; 2005 Nov; 48(22):7084-8. PubMed ID: 16250669
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
