BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 15274927)

  • 1. Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
    Worthylake DK; Rossman KL; Sondek J
    Structure; 2004 Jun; 12(6):1078-86. PubMed ID: 15274927
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
    Worthylake DK; Rossman KL; Sondek J
    Nature; 2000 Dec; 408(6813):682-8. PubMed ID: 11130063
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
    Wang L; Zhu K; Zheng Y
    Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
    Snyder JT; Worthylake DK; Rossman KL; Betts L; Pruitt WM; Siderovski DP; Der CJ; Sondek J
    Nat Struct Biol; 2002 Jun; 9(6):468-75. PubMed ID: 12006984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle.
    Derewenda U; Oleksy A; Stevenson AS; Korczynska J; Dauter Z; Somlyo AP; Otlewski J; Somlyo AV; Derewenda ZS
    Structure; 2004 Nov; 12(11):1955-65. PubMed ID: 15530360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activation.
    Chhatriwala MK; Betts L; Worthylake DK; Sondek J
    J Mol Biol; 2007 May; 368(5):1307-20. PubMed ID: 17391702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Critical role of the pleckstrin homology domain in Dbs signaling and growth regulation.
    Fuentes EJ; Karnoub AE; Booden MA; Der CJ; Campbell SL
    J Biol Chem; 2003 Jun; 278(23):21188-96. PubMed ID: 12637530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure and mutagenesis of the Dbl homology domain.
    Aghazadeh B; Zhu K; Kubiseski TJ; Liu GA; Pawson T; Zheng Y; Rosen MK
    Nat Struct Biol; 1998 Dec; 5(12):1098-107. PubMed ID: 9846881
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
    Rossman KL; Worthylake DK; Snyder JT; Siderovski DP; Campbell SL; Sondek J
    EMBO J; 2002 Mar; 21(6):1315-26. PubMed ID: 11889037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Cdc42 mutant specifically activated by intersectin.
    Smith WJ; Hamel B; Yohe ME; Sondek J; Cerione RA; Snyder JT
    Biochemistry; 2005 Oct; 44(40):13282-90. PubMed ID: 16201754
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes.
    Erickson JW; Cerione RA
    Biochemistry; 2004 Feb; 43(4):837-42. PubMed ID: 14744125
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro guanine nucleotide exchange activity of DHR-2/DOCKER/CZH2 domains.
    Côté JF; Vuori K
    Methods Enzymol; 2006; 406():41-57. PubMed ID: 16472648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity.
    Baumeister MA; Rossman KL; Sondek J; Lemmon MA
    Biochem J; 2006 Dec; 400(3):563-72. PubMed ID: 17007612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Larger than Dbl: new structural insights into RhoA activation.
    Rossman KL; Sondek J
    Trends Biochem Sci; 2005 Apr; 30(4):163-5. PubMed ID: 15817389
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation.
    Rossman KL; Cheng L; Mahon GM; Rojas RJ; Snyder JT; Whitehead IP; Sondek J
    J Biol Chem; 2003 May; 278(20):18393-400. PubMed ID: 12637522
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
    Kristelly R; Gao G; Tesmer JJ
    J Biol Chem; 2004 Nov; 279(45):47352-62. PubMed ID: 15331592
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of the Rho-specific guanine nucleotide-exchange factor Xpln.
    Murayama K; Kato-Murayama M; Akasaka R; Terada T; Yokoyama S; Shirouzu M
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Dec; 68(Pt 12):1455-9. PubMed ID: 23192023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Asef is a Cdc42-specific guanine nucleotide exchange factor.
    Gotthardt K; Ahmadian MR
    Biol Chem; 2007 Jan; 388(1):67-71. PubMed ID: 17214551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein.
    Soisson SM; Nimnual AS; Uy M; Bar-Sagi D; Kuriyan J
    Cell; 1998 Oct; 95(2):259-68. PubMed ID: 9790532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the SH3 domain of betaPIX in complex with a high affinity peptide from PAK2.
    Hoelz A; Janz JM; Lawrie SD; Corwin B; Lee A; Sakmar TP
    J Mol Biol; 2006 Apr; 358(2):509-22. PubMed ID: 16527308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.