BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 15279838)

  • 21. Construction of a human cytochrome P450 1A1: rat NADPH-cytochrome P450 reductase fusion protein cDNA and expression in Escherichia coli, purification, and catalytic properties of the enzyme in bacterial cells and after purification.
    Chun YJ; Shimada T; Guengerich FP
    Arch Biochem Biophys; 1996 Jun; 330(1):48-58. PubMed ID: 8651703
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.
    Josephy PD; Evans DH; Parikh A; Guengerich FP
    Chem Res Toxicol; 1998 Jan; 11(1):70-4. PubMed ID: 9477228
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Establishment of a Salmonella tester strain highly sensitive to mutagenic heterocylic amines.
    Kamataki T; Suzuki A; Kushida H; Iwata H; Watanabe M; Nohmi T; Fujita K
    Cancer Lett; 1999 Sep; 143(2):113-6. PubMed ID: 10503888
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
    Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
    Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
    Shimada T; Oda Y; Gillam EM; Guengerich FP; Inoue K
    Drug Metab Dispos; 2001 Sep; 29(9):1176-82. PubMed ID: 11502724
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5.
    Emmert B; Bünger J; Keuch K; Müller M; Emmert S; Hallier E; Westphal GA
    Toxicology; 2006 Nov; 228(1):66-76. PubMed ID: 16978761
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mutagenicity of aromatic amines and amides with chemical models for cytochrome P450 in Ames assay.
    Inami K; Okazawa M; Mochizuki M
    Toxicol In Vitro; 2009 Sep; 23(6):986-91. PubMed ID: 19563884
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Nitrogen-substitution effects on the mutagenicity and cytochrome P450 isoform-selectivity of chrysene analogs.
    Yamada K; Hakura A; Kato TA; Mizutani T; Saeki K
    Mutat Res; 2005 Sep; 586(1):87-95. PubMed ID: 16087391
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cytochrome b(5) coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium.
    Cooper MT; Porter TD
    Mutat Res; 2001 Dec; 484(1-2):61-8. PubMed ID: 11733072
    [TBL] [Abstract][Full Text] [Related]  

  • 30. High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli.
    Iwata H; Fujita K; Kushida H; Suzuki A; Konno Y; Nakamura K; Fujino A; Kamataki T
    Biochem Pharmacol; 1998 Apr; 55(8):1315-25. PubMed ID: 9719488
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes.
    Glatt H; Pabel U; Meinl W; Frederiksen H; Frandsen H; Muckel E
    Carcinogenesis; 2004 May; 25(5):801-7. PubMed ID: 14729582
    [TBL] [Abstract][Full Text] [Related]  

  • 32. High promutagen activating capacity of yeast microsomes containing human cytochrome P-450 1A and human NADPH-cytochrome P-450 reductase.
    Sengstag C; Eugster HP; Würgler FE
    Carcinogenesis; 1994 May; 15(5):837-43. PubMed ID: 8200084
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Development of a high-throughput genotoxicity assay using Umu test strains expressing human cytochrome P450s and NADPH-P450 reductase and bacterial O-acetyltransferase.
    Hori H; Hirata D; Fujii W; Oda Y
    Environ Mol Mutagen; 2017 May; 58(4):209-216. PubMed ID: 28436560
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of human cytochrome P450 isoforms and NADPH-CYP reductase in vitro by 15 herbal medicines, including Epimedii herba.
    Liu KH; Kim MJ; Jeon BH; Shon JH; Cha IJ; Cho KH; Lee SS; Shin JG
    J Clin Pharm Ther; 2006 Feb; 31(1):83-91. PubMed ID: 16476124
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines.
    Duarte MP; Palma BB; Laires A; Oliveira JS; Rueff J; Kranendonk M
    Mutagenesis; 2005 May; 20(3):199-208. PubMed ID: 15843388
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays.
    Inami K; Mochizuki M
    Mutat Res; 2002 Aug; 519(1-2):133-40. PubMed ID: 12160898
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Genetic polymorphism of CYP2A6 in relation to cancer.
    Kamataki T; Nunoya K; Sakai Y; Kushida H; Fujita K
    Mutat Res; 1999 Jul; 428(1-2):125-30. PubMed ID: 10517986
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C; Benyamina A; Llorca PM; Baylé F; Bromet N; Massiere F; Garay RP; Hameg A
    Eur J Pharm Sci; 2007 Dec; 32(4-5):357-66. PubMed ID: 17951033
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells.
    Uhl M; Ecker S; Kassie F; Lhoste E; Chakraborty A; Mohn G; Knasmüller S
    Arch Toxicol; 2003 Aug; 77(8):477-84. PubMed ID: 12856103
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Metabolism of promutagens catalyzed by Drosophila melanogaster CYP6A2 enzyme in Saccharomyces cerevisiae.
    Saner C; Weibel B; Wurgler FE; Sengstag C
    Environ Mol Mutagen; 1996; 27(1):46-58. PubMed ID: 8625948
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.