These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

466 related articles for article (PubMed ID: 15280393)

  • 1. Identification of Elongin C and Skp1 sequences that determine Cullin selection.
    Yan Q; Kamura T; Cai Y; Jin J; Ivan M; Mushegian A; Conaway RC; Conaway JW
    J Biol Chem; 2004 Oct; 279(41):43019-26. PubMed ID: 15280393
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
    Kamura T; Burian D; Yan Q; Schmidt SL; Lane WS; Querido E; Branton PE; Shilatifard A; Conaway RC; Conaway JW
    J Biol Chem; 2001 Aug; 276(32):29748-53. PubMed ID: 11384984
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase.
    Kamura T; Brower CS; Conaway RC; Conaway JW
    J Biol Chem; 2002 Aug; 277(33):30388-93. PubMed ID: 12048197
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2.
    Kamura T; Conrad MN; Yan Q; Conaway RC; Conaway JW
    Genes Dev; 1999 Nov; 13(22):2928-33. PubMed ID: 10579999
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
    Mahrour N; Redwine WB; Florens L; Swanson SK; Martin-Brown S; Bradford WD; Staehling-Hampton K; Washburn MP; Conaway RC; Conaway JW
    J Biol Chem; 2008 Mar; 283(12):8005-13. PubMed ID: 18187417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
    Brower CS; Sato S; Tomomori-Sato C; Kamura T; Pause A; Stearman R; Klausner RD; Malik S; Lane WS; Sorokina I; Roeder RG; Conaway JW; Conaway RC
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10353-8. PubMed ID: 12149480
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC; Astuti D; Hooper L; Maxwell PH; Ratcliffe PJ; Maher ER
    Oncogene; 2001 Aug; 20(36):5067-74. PubMed ID: 11526493
    [TBL] [Abstract][Full Text] [Related]  

  • 8. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
    Kamura T; Maenaka K; Kotoshiba S; Matsumoto M; Kohda D; Conaway RC; Conaway JW; Nakayama KI
    Genes Dev; 2004 Dec; 18(24):3055-65. PubMed ID: 15601820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase Skp1-cullin-F-box ligase (SCF) interact through multiple conformations.
    Sandoval D; Hill S; Ziemba A; Lewis S; Kuhlman B; Kleiger G
    J Biol Chem; 2015 Jan; 290(2):1106-18. PubMed ID: 25425648
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ; Ohh M; Moslehi J; Kondo K; Kaelin WG; Welch WJ
    Mol Cell Biol; 2002 Mar; 22(6):1947-60. PubMed ID: 11865071
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
    Kamura T; Koepp DM; Conrad MN; Skowyra D; Moreland RJ; Iliopoulos O; Lane WS; Kaelin WG; Elledge SJ; Conaway RC; Harper JW; Conaway JW
    Science; 1999 Apr; 284(5414):657-61. PubMed ID: 10213691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
    Zheng N; Schulman BA; Song L; Miller JJ; Jeffrey PD; Wang P; Chu C; Koepp DM; Elledge SJ; Pagano M; Conaway RC; Conaway JW; Harper JW; Pavletich NP
    Nature; 2002 Apr; 416(6882):703-9. PubMed ID: 11961546
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
    Seol JH; Feldman RM; Zachariae W; Shevchenko A; Correll CC; Lyapina S; Chi Y; Galova M; Claypool J; Sandmeyer S; Nasmyth K; Deshaies RJ; Shevchenko A; Deshaies RJ
    Genes Dev; 1999 Jun; 13(12):1614-26. PubMed ID: 10385629
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex.
    Iwai K; Yamanaka K; Kamura T; Minato N; Conaway RC; Conaway JW; Klausner RD; Pause A
    Proc Natl Acad Sci U S A; 1999 Oct; 96(22):12436-41. PubMed ID: 10535940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway.
    Lisztwan J; Marti A; Sutterlüty H; Gstaiger M; Wirbelauer C; Krek W
    EMBO J; 1998 Jan; 17(2):368-83. PubMed ID: 9430629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex.
    Cardote TAF; Gadd MS; Ciulli A
    Structure; 2017 Jun; 25(6):901-911.e3. PubMed ID: 28591624
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of elongin C sequences required for interaction with the von Hippel-Lindau tumor suppressor protein.
    Takagi Y; Pause A; Conaway RC; Conaway JW
    J Biol Chem; 1997 Oct; 272(43):27444-9. PubMed ID: 9341197
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein.
    Pause A; Peterson B; Schaffar G; Stearman R; Klausner RD
    Proc Natl Acad Sci U S A; 1999 Aug; 96(17):9533-8. PubMed ID: 10449727
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
    Skowyra D; Koepp DM; Kamura T; Conrad MN; Conaway RC; Conaway JW; Elledge SJ; Harper JW
    Science; 1999 Apr; 284(5414):662-5. PubMed ID: 10213692
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.
    Wu K; Fuchs SY; Chen A; Tan P; Gomez C; Ronai Z; Pan ZQ
    Mol Cell Biol; 2000 Feb; 20(4):1382-93. PubMed ID: 10648623
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.