133 related articles for article (PubMed ID: 15280442)
1. A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.
Bellocq C; Wilders R; Schott JJ; Louérat-Oriou B; Boisseau P; Le Marec H; Escande D; Baró I
Mol Pharmacol; 2004 Nov; 66(5):1093-102. PubMed ID: 15280442
[TBL] [Abstract][Full Text] [Related]
2. Mutant MiRP1 subunits modulate HERG K+ channel gating: a mechanism for pro-arrhythmia in long QT syndrome type 6.
Lu Y; Mahaut-Smith MP; Huang CL; Vandenberg JI
J Physiol; 2003 Aug; 551(Pt 1):253-62. PubMed ID: 12923204
[TBL] [Abstract][Full Text] [Related]
3. Pentamidine-induced long QT syndrome and block of hERG trafficking.
Kuryshev YA; Ficker E; Wang L; Hawryluk P; Dennis AT; Wible BA; Brown AM; Kang J; Chen XL; Sawamura K; Reynolds W; Rampe D
J Pharmacol Exp Ther; 2005 Jan; 312(1):316-23. PubMed ID: 15340016
[TBL] [Abstract][Full Text] [Related]
4. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
5. Cardiac glycosides as novel inhibitors of human ether-a-go-go-related gene channel trafficking.
Wang L; Wible BA; Wan X; Ficker E
J Pharmacol Exp Ther; 2007 Feb; 320(2):525-34. PubMed ID: 17095614
[TBL] [Abstract][Full Text] [Related]
6. Absence of clinically important HERG channel blockade by three compounds that inhibit phosphodiesterase 5--sildenafil, tadalafil, and vardenafil.
Dustan Sarazan R; Crumb WJ; Beasley CM; Emmick JT; Ferguson KM; Strnat CA; Sausen PJ
Eur J Pharmacol; 2004 Oct; 502(3):163-7. PubMed ID: 15476742
[TBL] [Abstract][Full Text] [Related]
7. Long QT syndrome in neonates: conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations.
Lupoglazoff JM; Denjoy I; Villain E; Fressart V; Simon F; Bozio A; Berthet M; Benammar N; Hainque B; Guicheney P
J Am Coll Cardiol; 2004 Mar; 43(5):826-30. PubMed ID: 14998624
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of human ether-a-go-go-related gene K+ channel and IKr of guinea pig cardiomyocytes by antipsychotic drug trifluoperazine.
Choi SY; Koh YS; Jo SH
J Pharmacol Exp Ther; 2005 May; 313(2):888-95. PubMed ID: 15722405
[TBL] [Abstract][Full Text] [Related]
9. QT prolongation through hERG K(+) channel blockade: current knowledge and strategies for the early prediction during drug development.
Recanatini M; Poluzzi E; Masetti M; Cavalli A; De Ponti F
Med Res Rev; 2005 Mar; 25(2):133-66. PubMed ID: 15389727
[TBL] [Abstract][Full Text] [Related]
10. Drug-induced QT interval prolongation--regulatory guidance and perspectives on hERG channel studies.
Shah RR
Novartis Found Symp; 2005; 266():251-80; discussion 280-5. PubMed ID: 16050273
[TBL] [Abstract][Full Text] [Related]
11. Molecular determinants of high-affinity drug binding to HERG channels.
Mitcheson JS; Perry MD
Curr Opin Drug Discov Devel; 2003 Sep; 6(5):667-74. PubMed ID: 14579516
[TBL] [Abstract][Full Text] [Related]
12. Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome.
Ohno S; Toyoda F; Zankov DP; Yoshida H; Makiyama T; Tsuji K; Honda T; Obayashi K; Ueyama H; Shimizu W; Miyamoto Y; Kamakura S; Matsuura H; Kita T; Horie M
Hum Mutat; 2009 Apr; 30(4):557-63. PubMed ID: 19306396
[TBL] [Abstract][Full Text] [Related]
13. Utility of hERG assays as surrogate markers of delayed cardiac repolarization and QT safety.
Gintant GA; Su Z; Martin RL; Cox BF
Toxicol Pathol; 2006; 34(1):81-90. PubMed ID: 16507548
[TBL] [Abstract][Full Text] [Related]
14. Expression of human ERG K+ channels in the mouse heart exerts anti-arrhythmic activity.
Royer A; Demolombe S; El Harchi A; Le Quang K; Piron J; Toumaniantz G; Mazurais D; Bellocq C; Lande G; Terrenoire C; Motoike HK; Chevallier JC; Loussouarn G; Clancy CE; Escande D; Charpentier F
Cardiovasc Res; 2005 Jan; 65(1):128-37. PubMed ID: 15621040
[TBL] [Abstract][Full Text] [Related]
15. Blockade of HERG human K+ channel and IKr of guinea pig cardiomyocytes by prochlorperazine.
Kim MD; Eun SY; Jo SH
Eur J Pharmacol; 2006 Aug; 544(1-3):82-90. PubMed ID: 16860311
[TBL] [Abstract][Full Text] [Related]
16. Clobutinol delays ventricular repolarization in the guinea pig heart: comparison with cardiac effects of HERG K+ channel inhibitor E-4031.
Takahara A; Sasaki R; Nakamura M; Sendo A; Sakurai Y; Namekata I; Tanaka H
J Cardiovasc Pharmacol; 2009 Dec; 54(6):552-9. PubMed ID: 19770670
[TBL] [Abstract][Full Text] [Related]
17. [HERG K+ channel, the target of anti-arrhythmias drugs].
Guan FY; Yang SJ
Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
[TBL] [Abstract][Full Text] [Related]
18. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.
Gordon E; Lozinskaya IM; Lin Z; Semus SF; Blaney FE; Willette RN; Xu X
Mol Pharmacol; 2008 Mar; 73(3):639-51. PubMed ID: 18042732
[TBL] [Abstract][Full Text] [Related]
19. The effects of sevoflurane and propofol on QT interval and heterologously expressed human ether-a-go-go related gene currents in Xenopus oocytes.
Yamada M; Hatakeyama N; Malykhina AP; Yamazaki M; Momose Y; Akbarali HI
Anesth Analg; 2006 Jan; 102(1):98-103. PubMed ID: 16368812
[TBL] [Abstract][Full Text] [Related]
20. Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.
Guo L; Guthrie H
J Pharmacol Toxicol Methods; 2005; 52(1):123-35. PubMed ID: 15936217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]