BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

602 related articles for article (PubMed ID: 15282207)

  • 1. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication.
    Sharma S; Sommers JA; Brosh RM
    Hum Mol Genet; 2004 Oct; 13(19):2247-61. PubMed ID: 15282207
    [TBL] [Abstract][Full Text] [Related]  

  • 2. WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.
    Sharma S; Otterlei M; Sommers JA; Driscoll HC; Dianov GL; Kao HI; Bambara RA; Brosh RM
    Mol Biol Cell; 2004 Feb; 15(2):734-50. PubMed ID: 14657243
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA.
    Sharma S; Sommers JA; Gary RK; Friedrich-Heineken E; Hübscher U; Brosh RM
    Nucleic Acids Res; 2005; 33(21):6769-81. PubMed ID: 16326861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of flap endonuclease-1 by the Bloom's syndrome protein.
    Sharma S; Sommers JA; Wu L; Bohr VA; Hickson ID; Brosh RM
    J Biol Chem; 2004 Mar; 279(11):9847-56. PubMed ID: 14688284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
    Aggarwal M; Brosh RM
    Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.
    Brosh RM; von Kobbe C; Sommers JA; Karmakar P; Opresko PL; Piotrowski J; Dianova I; Dianov GL; Bohr VA
    EMBO J; 2001 Oct; 20(20):5791-801. PubMed ID: 11598021
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical characterization of the WRN-FEN-1 functional interaction.
    Brosh RM; Driscoll HC; Dianov GL; Sommers JA
    Biochemistry; 2002 Oct; 41(40):12204-16. PubMed ID: 12356323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.
    Lee JW; Kusumoto R; Doherty KM; Lin GX; Zeng W; Cheng WH; von Kobbe C; Brosh RM; Hu JS; Bohr VA
    J Biol Chem; 2005 Nov; 280(47):39627-36. PubMed ID: 16150736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p53 modulates RPA-dependent and RPA-independent WRN helicase activity.
    Sommers JA; Sharma S; Doherty KM; Karmakar P; Yang Q; Kenny MK; Harris CC; Brosh RM
    Cancer Res; 2005 Feb; 65(4):1223-33. PubMed ID: 15735006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases.
    Doherty KM; Sommers JA; Gray MD; Lee JW; von Kobbe C; Thoma NH; Kureekattil RP; Kenny MK; Brosh RM
    J Biol Chem; 2005 Aug; 280(33):29494-505. PubMed ID: 15965237
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functions of RecQ family helicases: possible involvement of Bloom's and Werner's syndrome gene products in guarding genome integrity during DNA replication.
    Enomoto T
    J Biochem; 2001 Apr; 129(4):501-7. PubMed ID: 11275547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enzymatic mechanism of the WRN helicase/nuclease.
    Brosh RM; Opresko PL; Bohr VA
    Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 15. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
    Opresko PL; Mason PA; Podell ER; Lei M; Hickson ID; Cech TR; Bohr VA
    J Biol Chem; 2005 Sep; 280(37):32069-80. PubMed ID: 16030011
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Delineation of WRN helicase function with EXO1 in the replicational stress response.
    Aggarwal M; Sommers JA; Morris C; Brosh RM
    DNA Repair (Amst); 2010 Jul; 9(7):765-76. PubMed ID: 20447876
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination.
    Myung K; Datta A; Chen C; Kolodner RD
    Nat Genet; 2001 Jan; 27(1):113-6. PubMed ID: 11138010
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Functional analysis of yeast homologue gene associated with human DNA helicase causative syndromes].
    Miyajima A
    Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku; 2002; (120):53-74. PubMed ID: 12638184
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Localization of the Bloom syndrome helicase to punctate nuclear structures and the nuclear matrix and regulation during the cell cycle: comparison with the Werner's syndrome helicase.
    Gharibyan V; Youssoufian H
    Mol Carcinog; 1999 Dec; 26(4):261-73. PubMed ID: 10569803
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome.
    Trego KS; Chernikova SB; Davalos AR; Perry JJ; Finger LD; Ng C; Tsai MS; Yannone SM; Tainer JA; Campisi J; Cooper PK
    Cell Cycle; 2011 Jun; 10(12):1998-2007. PubMed ID: 21558802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.