These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

283 related articles for article (PubMed ID: 15292230)

  • 1. Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities.
    Tam EM; Moore TR; Butler GS; Overall CM
    J Biol Chem; 2004 Oct; 279(41):43336-44. PubMed ID: 15292230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage.
    Tam EM; Wu YI; Butler GS; Stack MS; Overall CM
    J Biol Chem; 2002 Oct; 277(41):39005-14. PubMed ID: 12145314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation.
    Overall CM; Tam E; McQuibban GA; Morrison C; Wallon UM; Bigg HF; King AE; Roberts CR
    J Biol Chem; 2000 Dec; 275(50):39497-506. PubMed ID: 10991943
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain.
    Patterson ML; Atkinson SJ; Knäuper V; Murphy G
    FEBS Lett; 2001 Aug; 503(2-3):158-62. PubMed ID: 11513874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contributions of the MMP-2 collagen binding domain to gelatin cleavage. Substrate binding via the collagen binding domain is required for hydrolysis of gelatin but not short peptides.
    Xu X; Wang Y; Lauer-Fields JL; Fields GB; Steffensen B
    Matrix Biol; 2004 Jun; 23(3):171-81. PubMed ID: 15296945
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Extracellular matrix binding properties of recombinant fibronectin type II-like modules of human 72-kDa gelatinase/type IV collagenase. High affinity binding to native type I collagen but not native type IV collagen.
    Steffensen B; Wallon UM; Overall CM
    J Biol Chem; 1995 May; 270(19):11555-66. PubMed ID: 7744795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase.
    Bigg HF; Morrison CJ; Butler GS; Bogoyevitch MA; Wang Z; Soloway PD; Overall CM
    Cancer Res; 2001 May; 61(9):3610-8. PubMed ID: 11325829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen.
    Wang P; Nie J; Pei D
    J Biol Chem; 2004 Dec; 279(49):51148-55. PubMed ID: 15381707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of collagen binding domain residues that govern catalytic activities of matrix metalloproteinase-2 (MMP-2).
    Mikhailova M; Xu X; Robichaud TK; Pal S; Fields GB; Steffensen B
    Matrix Biol; 2012; 31(7-8):380-8. PubMed ID: 23085623
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct roles for the catalytic and hemopexin domains of membrane type 1-matrix metalloproteinase in substrate degradation and cell migration.
    Cao J; Kozarekar P; Pavlaki M; Chiarelli C; Bahou WF; Zucker S
    J Biol Chem; 2004 Apr; 279(14):14129-39. PubMed ID: 14729674
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the mechanisms by which gelatinase A, neutrophil collagenase, and membrane-type metalloproteinase MMP-14 recognize collagen I and enzymatically process the two alpha-chains.
    Gioia M; Monaco S; Fasciglione GF; Coletti A; Modesti A; Marini S; Coletta M
    J Mol Biol; 2007 May; 368(4):1101-13. PubMed ID: 17379243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of membrane-type-1 matrix metalloproteinase activity by its cytoplasmic domain.
    Lehti K; Valtanen H; Wickström SA; Lohi J; Keski-Oja J
    J Biol Chem; 2000 May; 275(20):15006-13. PubMed ID: 10748199
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rac1 mediates type I collagen-dependent MMP-2 activation. role in cell invasion across collagen barrier.
    Zhuge Y; Xu J
    J Biol Chem; 2001 May; 276(19):16248-56. PubMed ID: 11340084
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression and purification of soluble and inactive mutant forms of membrane type 1 matrix metalloproteinase.
    Valtanen H; Lehti K; Lohi J; Keski-Oja J
    Protein Expr Purif; 2000 Jun; 19(1):66-73. PubMed ID: 10833392
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular determinants of metalloproteinase substrate specificity: matrix metalloproteinase substrate binding domains, modules, and exosites.
    Overall CM
    Mol Biotechnol; 2002 Sep; 22(1):51-86. PubMed ID: 12353914
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational and structural analyses of the hinge region of membrane type 1-matrix metalloproteinase and enzyme processing.
    Osenkowski P; Meroueh SO; Pavel D; Mobashery S; Fridman R
    J Biol Chem; 2005 Jul; 280(28):26160-8. PubMed ID: 15901740
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pivotal molecular determinants of peptidic and collagen triple helicase activities reside in the S3' subsite of matrix metalloproteinase 8 (MMP-8): the role of hydrogen bonding potential of ASN188 and TYR189 and the connecting cis bond.
    Pelman GR; Morrison CJ; Overall CM
    J Biol Chem; 2005 Jan; 280(3):2370-7. PubMed ID: 15533938
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional basis for the overlap in ligand interactions and substrate specificities of matrix metalloproteinases-9 and -2.
    Xu X; Chen Z; Wang Y; Yamada Y; Steffensen B
    Biochem J; 2005 Nov; 392(Pt 1):127-34. PubMed ID: 16008524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of zinc-binding- and hemopexin domain-encoded sequences in the substrate specificity of collagenase and stromelysin-2 as revealed by chimeric proteins.
    Sanchez-Lopez R; Alexander CM; Behrendtsen O; Breathnach R; Werb Z
    J Biol Chem; 1993 Apr; 268(10):7238-47. PubMed ID: 8463259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased matrix metalloproteinase-2 and membrane type 1 matrix metalloproteinase activity and expression in heterotopically transplanted murine tracheas.
    Inaki N; Tsunezuka Y; Kawakami K; Sato H; Takino T; Oda M; Watanabe G
    J Heart Lung Transplant; 2004 Feb; 23(2):218-27. PubMed ID: 14761770
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.