BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 15294457)

  • 1. Fenproporex N-dealkylation to amphetamine--enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats.
    Kraemer T; Pflugmann T; Bossmann M; Kneller NM; Peters FT; Paul LD; Springer D; Staack RF; Maurer HH
    Biochem Pharmacol; 2004 Sep; 68(5):947-57. PubMed ID: 15294457
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 dependent metabolism of the new designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP). In vivo studies in Wistar and Dark Agouti rats as well as in vitro studies in human liver microsomes.
    Staack RF; Paul LD; Springer D; Kraemer T; Maurer HH
    Biochem Pharmacol; 2004 Jan; 67(2):235-44. PubMed ID: 14698036
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the cytochrome P450 enzymes and enzyme kinetic parameters for metabolism of BVT.2938 using different in vitro systems.
    Baranczewski P; Edlund PO; Postlind H
    J Pharm Biomed Anal; 2006 Mar; 40(5):1121-30. PubMed ID: 16307862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The 1'-hydroxylation of Rac-bufuralol by rat brain microsomes.
    Coleman T; Spellman EF; Rostami-Hodjegan A; Lennard MS; Tucker GT
    Drug Metab Dispos; 2000 Sep; 28(9):1094-9. PubMed ID: 10950855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic kinetics of pseudoracemic propranolol in human liver microsomes. Enantioselectivity and quinidine inhibition.
    Marathe PH; Shen DD; Nelson WL
    Drug Metab Dispos; 1994; 22(2):237-47. PubMed ID: 8013280
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of N-substitution of 7-methoxy-4-(aminomethyl)-coumarin on cytochrome P450 metabolism and selectivity.
    Venhorst J; Onderwater RC; Meerman JH; Commandeur JN; Vermeulen NP
    Drug Metab Dispos; 2000 Dec; 28(12):1524-32. PubMed ID: 11095593
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Imipramine-induced inactivation of a cytochrome P450 2D enzyme in rat liver microsomes: in relation to covalent binding of its reactive intermediate.
    Masubuchi Y; Igarashi S; Suzuki T; Horie T; Narimatsu S
    J Pharmacol Exp Ther; 1996 Nov; 279(2):724-31. PubMed ID: 8930177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
    Ewald AH; Maurer HH
    Toxicol Lett; 2008 Dec; 183(1-3):52-7. PubMed ID: 18938231
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
    Herraiz T; Guillén H; Arán VJ; Idle JR; Gonzalez FJ
    Toxicol Appl Pharmacol; 2006 Nov; 216(3):387-98. PubMed ID: 16870220
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CYP2B6, CYP2D6, and CYP3A4 catalyze the primary oxidative metabolism of perhexiline enantiomers by human liver microsomes.
    Davies BJ; Coller JK; Somogyi AA; Milne RW; Sallustio BC
    Drug Metab Dispos; 2007 Jan; 35(1):128-38. PubMed ID: 17050648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
    Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.
    Akutsu T; Kobayashi K; Sakurada K; Ikegaya H; Furihata T; Chiba K
    Drug Metab Dispos; 2007 Jan; 35(1):72-8. PubMed ID: 17020955
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. XII. Enantioselectivity and temperature dependence in microsomes and reconstituted cytochrome P-450 systems from rat liver.
    Jönsson KH; Lindeke B
    Chirality; 1992; 4(8):469-77. PubMed ID: 1476856
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxy-methamphetamine and its enantiomers.
    Meyer MR; Peters FT; Maurer HH
    Drug Metab Dispos; 2008 Nov; 36(11):2345-54. PubMed ID: 18725511
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
    Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
    Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective involvement of cytochrome P450 2D subfamily in in vivo 4-hydroxylation of amphetamine in rat.
    Law MY; Slawson MH; Moody DE
    Drug Metab Dispos; 2000 Mar; 28(3):348-53. PubMed ID: 10681381
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA.
    Gollamudi R; Ali SF; Lipe G; Newport G; Webb P; Lopez M; Leakey JE; Kolta M; Slikker W
    Neurotoxicology; 1989; 10(3):455-66. PubMed ID: 2576302
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes.
    Springer D; Paul LD; Staack RF; Kraemer T; Maurer HH
    Drug Metab Dispos; 2003 Aug; 31(8):979-82. PubMed ID: 12867484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereoselective differences in the cytochrome P450-dependent dealkylation and demethylenation of N-methyl-benzodioxolyl-butanamine (MBDB, Eden) enantiomers.
    Meyer MR; Peters FT; Maurer HH
    Biochem Pharmacol; 2009 Jun; 77(11):1725-34. PubMed ID: 19428327
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of the enantioselective oxidative metabolism of metoprolol by verapamil in human liver microsomes.
    Kim M; Shen DD; Eddy AC; Nelson WL; Roskos LK
    Drug Metab Dispos; 1993; 21(2):309-17. PubMed ID: 8097702
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.