BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

936 related articles for article (PubMed ID: 15294875)

  • 1. Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status.
    Oliveira C; Westra JL; Arango D; Ollikainen M; Domingo E; Ferreira A; Velho S; Niessen R; Lagerstedt K; Alhopuro P; Laiho P; Veiga I; Teixeira MR; Ligtenberg M; Kleibeuker JH; Sijmons RH; Plukker JT; Imai K; Lage P; Hamelin R; Albuquerque C; Schwartz S; Lindblom A; Peltomaki P; Yamamoto H; Aaltonen LA; Seruca R; Hofstra RM
    Hum Mol Genet; 2004 Oct; 13(19):2303-11. PubMed ID: 15294875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers.
    Yuen ST; Chan TL; Ho JW; Chan AS; Chung LP; Lam PW; Tse CW; Wyllie AH; Leung SY
    Oncogene; 2002 Oct; 21(49):7585-92. PubMed ID: 12386821
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.
    Cunningham JM; Christensen ER; Tester DJ; Kim CY; Roche PC; Burgart LJ; Thibodeau SN
    Cancer Res; 1998 Aug; 58(15):3455-60. PubMed ID: 9699680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas.
    Koinuma K; Shitoh K; Miyakura Y; Furukawa T; Yamashita Y; Ota J; Ohki R; Choi YL; Wada T; Konishi F; Nagai H; Mano H
    Int J Cancer; 2004 Jan; 108(2):237-42. PubMed ID: 14639609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis.
    Young J; Simms LA; Biden KG; Wynter C; Whitehall V; Karamatic R; George J; Goldblatt J; Walpole I; Robin SA; Borten MM; Stitz R; Searle J; McKeone D; Fraser L; Purdie DR; Podger K; Price R; Buttenshaw R; Walsh MD; Barker M; Leggett BA; Jass JR
    Am J Pathol; 2001 Dec; 159(6):2107-16. PubMed ID: 11733361
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of mutator pathway in younger-age-onset colorectal adenocarcinomas.
    Roh SA; Kim HC; Kim JS; Kim JC
    J Korean Med Sci; 2003 Jun; 18(3):387-91. PubMed ID: 12808326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutational analysis of promoters of mismatch repair genes hMSH2 and hMLH1 in hereditary nonpolyposis colorectal cancer and early onset colorectal cancer patients: identification of three novel germ-line mutations in promoter of the hMSH2 gene.
    Shin KH; Shin JH; Kim JH; Park JG
    Cancer Res; 2002 Jan; 62(1):38-42. PubMed ID: 11782355
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinction of hereditary nonpolyposis colorectal cancer and sporadic microsatellite-unstable colorectal cancer through quantification of MLH1 methylation by real-time PCR.
    Bettstetter M; Dechant S; Ruemmele P; Grabowski M; Keller G; Holinski-Feder E; Hartmann A; Hofstaedter F; Dietmaier W
    Clin Cancer Res; 2007 Jun; 13(11):3221-8. PubMed ID: 17545526
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The frequency of hereditary defective mismatch repair in a prospective series of unselected colorectal carcinomas.
    Cunningham JM; Kim CY; Christensen ER; Tester DJ; Parc Y; Burgart LJ; Halling KC; McDonnell SK; Schaid DJ; Walsh Vockley C; Kubly V; Nelson H; Michels VV; Thibodeau SN
    Am J Hum Genet; 2001 Oct; 69(4):780-90. PubMed ID: 11524701
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Causes of microsatellite instability in colorectal tumors: implications for hereditary non-polyposis colorectal cancer screening.
    Potocnik U; Glavac D; Golouh R; Ravnik-Glavac M
    Cancer Genet Cytogenet; 2001 Apr; 126(2):85-96. PubMed ID: 11376800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: genetic reclassification and correlation with clinical features.
    Schiemann U; Müller-Koch Y; Gross M; Daum J; Lohse P; Baretton G; Muders M; Mussack T; Kopp R; Holinski-Feder E
    Digestion; 2004; 69(3):166-76. PubMed ID: 15118395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancer.
    Deng G; Bell I; Crawley S; Gum J; Terdiman JP; Allen BA; Truta B; Sleisenger MH; Kim YS
    Clin Cancer Res; 2004 Jan; 10(1 Pt 1):191-5. PubMed ID: 14734469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high-level microsatellite instability.
    Bevilacqua RA; Simpson AJ
    Int J Cancer; 2000 Jul; 87(2):200-3. PubMed ID: 10861474
    [TBL] [Abstract][Full Text] [Related]  

  • 14. hMLH1 and hMSH2 expression in human hepatocellular carcinoma.
    Wang L; Bani-Hani A; Montoya DP; Roche PC; Thibodeau SN; Burgart LJ; Roberts LR
    Int J Oncol; 2001 Sep; 19(3):567-70. PubMed ID: 11494037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRAF mutations in colorectal carcinoma suggest two entities of microsatellite-unstable tumors.
    Lubomierski N; Plotz G; Wormek M; Engels K; Kriener S; Trojan J; Jungling B; Zeuzem S; Raedle J
    Cancer; 2005 Sep; 104(5):952-61. PubMed ID: 16015629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mismatch repair gene expression defects contribute to microsatellite instability in ovarian carcinoma.
    Geisler JP; Goodheart MJ; Sood AK; Holmes RJ; Hatterman-Zogg MA; Buller RE
    Cancer; 2003 Nov; 98(10):2199-206. PubMed ID: 14601090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study.
    Stefansson I; Akslen LA; MacDonald N; Ryan A; Das S; Jacobs IJ; Salvesen HB
    Clin Cancer Res; 2002 Jan; 8(1):138-43. PubMed ID: 11801550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extensive molecular screening for hereditary non-polyposis colorectal cancer.
    Dieumegard B; Grandjouan S; Sabourin JC; Le Bihan ML; Lefrère I; Bellefqih ; Pignon JP; Rougier P; Lasser P; Bénard J; Couturier D; Bressac-de Paillerets B
    Br J Cancer; 2000 Feb; 82(4):871-80. PubMed ID: 10732761
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Clinical features and mismatch repair gene mutation screening in Chinese patients with hereditary nonpolyposis colorectal carcinoma.
    Liu SR; Zhao B; Wang ZJ; Wan YL; Huang YT
    World J Gastroenterol; 2004 Sep; 10(18):2647-51. PubMed ID: 15309712
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression.
    Scartozzi M; Bianchi F; Rosati S; Galizia E; Antolini A; Loretelli C; Piga A; Bearzi I; Cellerino R; Porfiri E
    J Clin Oncol; 2002 Mar; 20(5):1203-8. PubMed ID: 11870161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.