275 related articles for article (PubMed ID: 15296735)
1. Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites.
Goto M; Omi R; Nakagawa N; Miyahara I; Hirotsu K
Structure; 2004 Aug; 12(8):1413-23. PubMed ID: 15296735
[TBL] [Abstract][Full Text] [Related]
2. Mutational analysis of conserved glycine residues 142, 143 and 146 reveals Gly(142) is critical for tetramerization of CTP synthase from Escherichia coli.
Lunn FA; Macleod TJ; Bearne SL
Biochem J; 2008 May; 412(1):113-21. PubMed ID: 18260824
[TBL] [Abstract][Full Text] [Related]
3. GTP-Dependent Regulation of CTP Synthase: Evolving Insights into Allosteric Activation and NH
Bearne SL; Guo CJ; Liu JL
Biomolecules; 2022 Apr; 12(5):. PubMed ID: 35625575
[TBL] [Abstract][Full Text] [Related]
4. Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
Simard D; Hewitt KA; Lunn F; Iyengar A; Bearne SL
Eur J Biochem; 2003 May; 270(10):2195-206. PubMed ID: 12752439
[TBL] [Abstract][Full Text] [Related]
5. Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity.
Willemoës M; Mølgaard A; Johansson E; Martinussen J
FEBS J; 2005 Feb; 272(3):856-64. PubMed ID: 15670165
[TBL] [Abstract][Full Text] [Related]
6. Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.
Iyengar A; Bearne SL
Biochem J; 2003 Feb; 369(Pt 3):497-507. PubMed ID: 12383057
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotransferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targets.
Endrizzi JA; Kim H; Anderson PM; Baldwin EP
Biochemistry; 2004 Jun; 43(21):6447-63. PubMed ID: 15157079
[TBL] [Abstract][Full Text] [Related]
8. Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase.
Willemoës M
Arch Biochem Biophys; 2004 Apr; 424(1):105-11. PubMed ID: 15019842
[TBL] [Abstract][Full Text] [Related]
9. "Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
McCluskey GD; Bearne SL
Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2714-2727. PubMed ID: 30251661
[TBL] [Abstract][Full Text] [Related]
10. The role of lysine residues 297 and 306 in nucleoside triphosphate regulation of E. coli CTP synthase: inactivation by 2',3'-dialdehyde ATP and mutational analyses.
MacLeod TJ; Lunn FA; Bearne SL
Biochim Biophys Acta; 2006 Feb; 1764(2):199-210. PubMed ID: 16427816
[TBL] [Abstract][Full Text] [Related]
11. Alternative substrates for wild-type and L109A E. coli CTP synthases: kinetic evidence for a constricted ammonia tunnel.
Lunn FA; Bearne SL
Eur J Biochem; 2004 Nov; 271(21):4204-12. PubMed ID: 15511226
[TBL] [Abstract][Full Text] [Related]
12. Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography.
Anand R; Hoskins AA; Stubbe J; Ealick SE
Biochemistry; 2004 Aug; 43(32):10328-42. PubMed ID: 15301531
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for ligand binding modes of CTP synthase.
Zhou X; Guo CJ; Chang CC; Zhong J; Hu HH; Lu GM; Liu JL
Proc Natl Acad Sci U S A; 2021 Jul; 118(30):. PubMed ID: 34301892
[TBL] [Abstract][Full Text] [Related]
14. Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy.
Kursula P; Flodin S; Ehn M; Hammarström M; Schüler H; Nordlund P; Stenmark P
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2006 Jul; 62(Pt 7):613-7. PubMed ID: 16820675
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP.
MacDonnell JE; Lunn FA; Bearne SL
Biochim Biophys Acta; 2004 Jun; 1699(1-2):213-20. PubMed ID: 15158730
[TBL] [Abstract][Full Text] [Related]
16. Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis.
Willemoës M; Sigurskjold BW
Eur J Biochem; 2002 Oct; 269(19):4772-9. PubMed ID: 12354108
[TBL] [Abstract][Full Text] [Related]
17. Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative.
Tanaka Y; Nakagawa N; Kuramitsu S; Yokoyama S; Masui R
J Biochem; 2005 Sep; 138(3):263-75. PubMed ID: 16169877
[TBL] [Abstract][Full Text] [Related]
18. Identification of Ser424 as the protein kinase A phosphorylation site in CTP synthetase from Saccharomyces cerevisiae.
Park TS; Ostrander DB; Pappas A; Carman GM
Biochemistry; 1999 Jul; 38(27):8839-48. PubMed ID: 10393561
[TBL] [Abstract][Full Text] [Related]
19. Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax.
Lunn FA; MacDonnell JE; Bearne SL
J Biol Chem; 2008 Jan; 283(4):2010-20. PubMed ID: 18003612
[TBL] [Abstract][Full Text] [Related]
20. ATP-induced structural change of dephosphocoenzyme A kinase from Thermus thermophilus HB8.
Seto A; Murayama K; Toyama M; Ebihara A; Nakagawa N; Kuramitsu S; Shirouzu M; Yokoyama S
Proteins; 2005 Jan; 58(1):235-42. PubMed ID: 15526298
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
