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8. The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. Zhang JG; Farley A; Nicholson SE; Willson TA; Zugaro LM; Simpson RJ; Moritz RL; Cary D; Richardson R; Hausmann G; Kile BT; Kent SB; Alexander WS; Metcalf D; Hilton DJ; Nicola NA; Baca M Proc Natl Acad Sci U S A; 1999 Mar; 96(5):2071-6. PubMed ID: 10051596 [TBL] [Abstract][Full Text] [Related]
9. A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box. Hanada T; Yoshida T; Kinjyo I; Minoguchi S; Yasukawa H; Kato S; Mimata H; Nomura Y; Seki Y; Kubo M; Yoshimura A J Biol Chem; 2001 Nov; 276(44):40746-54. PubMed ID: 11522790 [TBL] [Abstract][Full Text] [Related]
10. A three-dimensional model of Suppressor Of Cytokine Signalling 1 (SOCS-1). Giordanetto F; Kroemer RT Protein Eng; 2003 Feb; 16(2):115-24. PubMed ID: 12676980 [TBL] [Abstract][Full Text] [Related]
11. Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation. Frantsve J; Schwaller J; Sternberg DW; Kutok J; Gilliland DG Mol Cell Biol; 2001 May; 21(10):3547-57. PubMed ID: 11313480 [TBL] [Abstract][Full Text] [Related]
12. The suppressors of cytokine signalling (SOCS). Kile BT; Alexander WS Cell Mol Life Sci; 2001 Oct; 58(11):1627-35. PubMed ID: 11706989 [TBL] [Abstract][Full Text] [Related]
13. Functional involvement of Akt signaling downstream of Jak1 in v-Abl-induced activation of hematopoietic cells. Oki S; Limnander A; Danial NN; Rothman PB Blood; 2002 Aug; 100(3):966-73. PubMed ID: 12130510 [TBL] [Abstract][Full Text] [Related]
15. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families. Kamura T; Sato S; Haque D; Liu L; Kaelin WG; Conaway RC; Conaway JW Genes Dev; 1998 Dec; 12(24):3872-81. PubMed ID: 9869640 [TBL] [Abstract][Full Text] [Related]
16. Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line. To KF; Chan MW; Leung WK; Ng EK; Yu J; Bai AH; Lo AW; Chu SH; Tong JH; Lo KW; Sung JJ; Chan FK Br J Cancer; 2004 Oct; 91(7):1335-41. PubMed ID: 15354212 [TBL] [Abstract][Full Text] [Related]
17. SOCS-1 suppresses TNF-alpha-induced apoptosis through the regulation of Jak activation. Kimura A; Naka T; Nagata S; Kawase I; Kishimoto T Int Immunol; 2004 Jul; 16(7):991-9. PubMed ID: 15173123 [TBL] [Abstract][Full Text] [Related]
18. Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation. Danial NN; Losman JA; Lu T; Yip N; Krishnan K; Krolewski J; Goff SP; Wang JY; Rothman PB Mol Cell Biol; 1998 Nov; 18(11):6795-804. PubMed ID: 9774693 [TBL] [Abstract][Full Text] [Related]
19. Modulation of Janus kinase 2 by cisplatin in cancer cells. Song H; Sondak VK; Barber DL; Reid TJ; Lin J Int J Oncol; 2004 Apr; 24(4):1017-26. PubMed ID: 15010843 [TBL] [Abstract][Full Text] [Related]
20. Distinct activities of suppressor of cytokine signaling (SOCS) proteins and involvement of the SOCS box in controlling G-CSF signaling. van de Geijn GJ; Gits J; Touw IP J Leukoc Biol; 2004 Jul; 76(1):237-44. PubMed ID: 15107455 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]