These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

411 related articles for article (PubMed ID: 1530660)

  • 21. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Highly sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM3009 having high O-acetyltransferase and nitroreductase activities.
    Oda Y; Yamazaki H; Watanabe M; Nohmi T; Shimada T
    Environ Mol Mutagen; 1993; 21(4):357-64. PubMed ID: 8491215
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
    Chae YH; Yun CH; Guengerich FP; Kadlubar FF; el-Bayoumy K
    Cancer Res; 1993 May; 53(9):2028-34. PubMed ID: 8481905
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes.
    Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T
    Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.
    Shimada T; Iwasaki M; Martin MV; Guengerich FP
    Cancer Res; 1989 Jun; 49(12):3218-28. PubMed ID: 2655891
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Immunochemical detection and quantitation of microsomal cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate:cytochrome P-450 reductase in the rat ventral prostate.
    Haaparanta T; Halpert J; Glaumann H; Gustafsson JA
    Cancer Res; 1983 Nov; 43(11):5131-7. PubMed ID: 6413054
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Hydrogen peroxide supports human and rat cytochrome P450 1A2-catalyzed 2-amino-3-methylimidazo[4,5-f]quinoline bioactivation to mutagenic metabolites: significance of cytochrome P450 peroxygenase.
    Anari MR; Josephy PD; Henry T; O'Brien PJ
    Chem Res Toxicol; 1997 May; 10(5):582-8. PubMed ID: 9168257
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mutagenic activation of aflatoxin B1 by pulmonary, renal, and hepatic cytochrome P450s from rats.
    Imaoka S; Ikemoto S; Shimada T; Funae Y
    Mutat Res; 1992 Oct; 269(2):231-6. PubMed ID: 1383706
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Catalysis of the oxidation of steroid and stilbene estrogens to estrogen quinone metabolites by the beta-naphthoflavone-inducible cytochrome P450 IA family.
    Roy D; Bernhardt A; Strobel HW; Liehr JG
    Arch Biochem Biophys; 1992 Aug; 296(2):450-6. PubMed ID: 1632637
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.
    Shimada T; El-Bayoumy K; Upadhyaya P; Sutter TR; Guengerich FP; Yamazaki H
    Cancer Res; 1997 Nov; 57(21):4757-64. PubMed ID: 9354437
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002.
    Shimada T; Nakamura S
    Biochem Pharmacol; 1987 Jun; 36(12):1979-87. PubMed ID: 3297069
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains.
    Oda Y; Totsuka Y; Wakabayashi K; Guengerich FP; Shimada T
    Mutagenesis; 2006 Nov; 21(6):411-6. PubMed ID: 17067997
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The spectrum of enzymes involved in activation of 2-aminoanthracene varies with the metabolic system applied.
    Veres Z; Török G; Tóth E; Vereczkey L; Jemnitz K
    Mutat Res; 2005 Sep; 586(1):18-27. PubMed ID: 16006184
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T; Yamazaki H; Mimura M; Wakamiya N; Ueng YF; Guengerich FP; Inui Y
    Drug Metab Dispos; 1996 May; 24(5):515-22. PubMed ID: 8723730
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
    Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
    Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dose-dependent, mechanism-based inactivation of cytochrome P450 monooxygenases in vivo by 1-aminobenzotriazole in liver, lung, and kidney of untreated, phenobarbital-treated, and beta-naphthoflavone-treated guinea pigs.
    Knickle LC; Bend JR
    Can J Physiol Pharmacol; 1992 Dec; 70(12):1610-7. PubMed ID: 1301239
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.
    Shimada T; Okuda Y
    Biochem Pharmacol; 1988 Feb; 37(3):459-65. PubMed ID: 3337745
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Modification of the mutagenicity and teratogenicity of cyclophosphamide in rats with inducers of the cytochromes P-450.
    Hales BF
    Teratology; 1981 Aug; 24(1):1-11. PubMed ID: 7029774
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung.
    Baum M; Amin S; Guengerich FP; Hecht SS; Köhl W; Eisenbrand G
    Chem Res Toxicol; 2001 Jun; 14(6):686-93. PubMed ID: 11409939
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Activation of the anti-cancer drug ifosphamide by rat liver microsomal P450 enzymes.
    Weber GF; Waxman DJ
    Biochem Pharmacol; 1993 Apr; 45(8):1685-94. PubMed ID: 8484807
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.