BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 15316010)

  • 1. Development and refinement of pregnane X receptor (PXR) DNA binding site model using information theory: insights into PXR-mediated gene regulation.
    Vyhlidal CA; Rogan PK; Leeder JS
    J Biol Chem; 2004 Nov; 279(45):46779-86. PubMed ID: 15316010
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.
    Bhalla S; Ozalp C; Fang S; Xiang L; Kemper JK
    J Biol Chem; 2004 Oct; 279(43):45139-47. PubMed ID: 15322103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
    Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
    J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands.
    Toell A; Kröncke KD; Kleinert H; Carlberg C
    J Cell Biochem; 2002; 85(1):72-82. PubMed ID: 11891851
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis.
    Frank C; Makkonen H; Dunlop TW; Matilainen M; Väisänen S; Carlberg C
    J Mol Biol; 2005 Feb; 346(2):505-19. PubMed ID: 15670600
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pregnane X receptor is a target of farnesoid X receptor.
    Jung D; Mangelsdorf DJ; Meyer UA
    J Biol Chem; 2006 Jul; 281(28):19081-91. PubMed ID: 16682417
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.
    Sugatani J; Uchida T; Kurosawa M; Yamaguchi M; Yamazaki Y; Ikari A; Miwa M
    Drug Metab Dispos; 2012 Oct; 40(10):2031-40. PubMed ID: 22829544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
    Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Statins Increase Plasminogen Activator Inhibitor Type 1 Gene Transcription through a Pregnane X Receptor Regulated Element.
    Stanley FM; Linder KM; Cardozo TJ
    PLoS One; 2015; 10(9):e0138097. PubMed ID: 26379245
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
    Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
    Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of rat organic anion transporting polypeptide 2 by pregnenolone-16alpha-carbonitrile is via interaction with pregnane X receptor.
    Guo GL; Staudinger J; Ogura K; Klaassen CD
    Mol Pharmacol; 2002 Apr; 61(4):832-9. PubMed ID: 11901222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3.
    Thummel KE; Brimer C; Yasuda K; Thottassery J; Senn T; Lin Y; Ishizuka H; Kharasch E; Schuetz J; Schuetz E
    Mol Pharmacol; 2001 Dec; 60(6):1399-406. PubMed ID: 11723248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heterodimerization of Retinoid X Receptor with Xenobiotic Receptor partners occurs in the cytoplasmic compartment: Mechanistic insights of events in living cells.
    Dash AK; Yende AS; Jaiswal B; Tyagi RK
    Exp Cell Res; 2017 Nov; 360(2):337-346. PubMed ID: 28939253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.
    Falkner KC; Pinaire JA; Xiao GH; Geoghegan TE; Prough RA
    Mol Pharmacol; 2001 Sep; 60(3):611-9. PubMed ID: 11502894
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
    Kliewer SA; Goodwin B; Willson TM
    Endocr Rev; 2002 Oct; 23(5):687-702. PubMed ID: 12372848
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR; Goodwin B; Tarr PT; Jones SA; Anisfeld AM; Stoltz CM; Tontonoz P; Kliewer S; Willson TM; Edwards PA
    J Biol Chem; 2002 Jan; 277(4):2908-15. PubMed ID: 11706036
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor.
    Laffitte BA; Kast HR; Nguyen CM; Zavacki AM; Moore DD; Edwards PA
    J Biol Chem; 2000 Apr; 275(14):10638-47. PubMed ID: 10744760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.
    Gu X; Ke S; Liu D; Sheng T; Thomas PE; Rabson AB; Gallo MA; Xie W; Tian Y
    J Biol Chem; 2006 Jun; 281(26):17882-9. PubMed ID: 16608838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.
    Lin YS; Yasuda K; Assem M; Cline C; Barber J; Li CW; Kholodovych V; Ai N; Chen JD; Welsh WJ; Ekins S; Schuetz EG
    Drug Metab Dispos; 2009 Jun; 37(6):1295-304. PubMed ID: 19251824
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.
    Zhang J; Kuehl P; Green ED; Touchman JW; Watkins PB; Daly A; Hall SD; Maurel P; Relling M; Brimer C; Yasuda K; Wrighton SA; Hancock M; Kim RB; Strom S; Thummel K; Russell CG; Hudson JR; Schuetz EG; Boguski MS
    Pharmacogenetics; 2001 Oct; 11(7):555-72. PubMed ID: 11668216
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.