These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 1531872)

  • 1. Modulation of neocarzinostatin-mediated DNA double strand damage by activating thiol: deuterium isotope effects.
    McAfee SE; Ashley GW
    Nucleic Acids Res; 1992 Feb; 20(4):805-9. PubMed ID: 1531872
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective abstraction of 2H from C-1' of the C residue in AGC.ICT by the radical center at C-2 of activated neocarzinostatin chromophore: structure of the drug/DNA complex responsible for bistranded lesion formation.
    Meschwitz SM; Schultz RG; Ashley GW; Goldberg IH
    Biochemistry; 1992 Sep; 31(38):9117-21. PubMed ID: 1390698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Double-stranded damage of DNA.RNA hybrids by neocarzinostatin chromophore: selective C-1' chemistry on the RNA strand.
    Zeng X; Xi Z; Kappen LS; Tan W; Goldberg IH
    Biochemistry; 1995 Sep; 34(38):12435-44. PubMed ID: 7547989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site.
    Dedon PC; Goldberg IH
    J Biol Chem; 1990 Sep; 265(25):14713-6. PubMed ID: 2144279
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neocarzinostatin acts as a sensitive probe of DNA microheterogeneity: switching of chemistry from C-1' to C-4' by a G.T mismatch 5' to the site of DNA damage.
    Kappen LS; Goldberg IH
    Proc Natl Acad Sci U S A; 1992 Aug; 89(15):6706-10. PubMed ID: 1386670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bulge-specific cleavage in transactivation response region RNA and its DNA analogue by neocarzinostatin chromophore.
    Kappen LS; Goldberg IH
    Biochemistry; 1995 May; 34(17):5997-6002. PubMed ID: 7537097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective abstraction of 2H from C-5' of thymidylate in an oligodeoxynucleotide by the radical center at C-6 of the diradical species of neocarzinostatin: chemical evidence for the structure of the activated drug-DNA complex.
    Meschwitz SM; Goldberg IH
    Proc Natl Acad Sci U S A; 1991 Apr; 88(8):3047-51. PubMed ID: 1826561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neocarzinostatin-mediated DNA damage in a model AGT.ACT site: mechanistic studies of thiol-sensitive partitioning of C4' DNA damage products.
    Dedon PC; Jiang ZW; Goldberg IH
    Biochemistry; 1992 Feb; 31(7):1917-27. PubMed ID: 1531616
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neocarzinostatin-induced hydrogen atom abstraction from C-4' and C-5' of the T residue at a d(GT) step in oligonucleotides: shuttling between deoxyribose attack sites based on isotope selection effects.
    Kappen LS; Goldberg IH; Frank BL; Worth L; Christner DF; Kozarich JW; Stubbe J
    Biochemistry; 1991 Feb; 30(8):2034-42. PubMed ID: 1825606
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular models of neocarzinostatin damage of DNA: analysis of sequence dependence in 5'GAGCG:5'CGCTC.
    Galat A; Goldberg IH
    Nucleic Acids Res; 1990 Apr; 18(8):2093-9. PubMed ID: 2139934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sources of hydrogen abstraction by activated neocarzinostatin chromophore.
    Chin DH; Goldberg IH
    Biochemistry; 1993 Apr; 32(14):3611-6. PubMed ID: 8466903
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A single binding mode of activated enediyne C1027 generates two types of double-strand DNA lesions: deuterium isotope-induced shuttling between adjacent nucleotide target sites.
    Xu YJ; Xi Z; Zhen YS; Goldberg IH
    Biochemistry; 1995 Sep; 34(38):12451-60. PubMed ID: 7547991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neocarzinostatin-induced DNA base release accompanied by staggered oxidative cleavage of the complementary strand.
    Povirk LF; Houlgrave CW; Han YH
    J Biol Chem; 1988 Dec; 263(36):19263-6. PubMed ID: 2974036
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Free radical mechanisms in neocarzinostatin-induced DNA damage.
    Goldberg IH
    Free Radic Biol Med; 1987; 3(1):41-54. PubMed ID: 2957284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generation of superoxide free radical by neocarzinostatin and its possible role in DNA damage.
    Chin DH; Goldberg IH
    Biochemistry; 1986 Mar; 25(5):1009-15. PubMed ID: 3008815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of a novel covalent monoadduct on the RNA overhang of an RNA-DNA hybrid induced by antitumor antibiotic neocarzinostatin.
    Zheng P; Liu CL; Xi Z; Smith RD; Goldberg IH
    Biochemistry; 1998 Feb; 37(6):1706-13. PubMed ID: 9484242
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5' of deoxyribose.
    Kappen LS; Goldberg IH
    Biochemistry; 1983 Oct; 22(21):4872-8. PubMed ID: 6227335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Light-induced DNA cleavage by esperamicin and neocarzinostatin.
    Uesawa Y; Kuwahara J; Sugiura Y
    Biochem Biophys Res Commun; 1989 Oct; 164(2):903-11. PubMed ID: 2554905
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing DNA single strands for single-base bulges with neocarzinostatin chromophore.
    Kappen LS; Xi Z; Goldberg IH
    Biochemistry; 2001 Dec; 40(50):15378-83. PubMed ID: 11735421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage.
    Kappen LS; Goldberg IH
    Proc Natl Acad Sci U S A; 1984 Jun; 81(11):3312-6. PubMed ID: 6233608
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.